Clinical trials
Alzheimer's Disease Dementia clinical trials
Below are recruiting alzheimer's disease dementia clinical trials, each written for real people, not researchers. We’re tracking 471 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07780383RecruitingPhase 1
Single-dose study for healthy adults and early Alzheimer's participants
This trial tests a new investigational drug, BMS-986446, given as a single dose to healthy volunteers and multiple doses to people with early Alzheimer's disease. It aims to understand how the drug moves in the body, its safety, and whether it triggers an immune response, which could help guide future treatment for Alzheimer's.
Anaheim, CaliforniaAges 18–80 - NCT07512362RecruitingPhase 2
Stem cells and antibodies for early Alzheimer's disease
This study tests whether human stem cells, combined with your existing Alzheimer's medication (Leqembi or Kisunla), can help slow memory loss and improve daily functioning in people with mild cognitive impairment or early Alzheimer's. You would receive a stem cell infusion as an add-on to your current treatment.
Miami, FloridaAges 55–90 - NCT07033494RecruitingPhase 2
Study of MK-2214 for early Alzheimer's disease
This trial tests an experimental medicine called MK-2214 for people with early Alzheimer's (mild cognitive impairment or mild dementia). The goal is to see if it can slow memory and thinking problems.
Irvine, CaliforniaAges 50–85 - NCT06887192RecruitingPhase 2
Testing ML-007C-MA for Alzheimer's Psychosis
This trial tests a study drug called ML-007C-MA to see if it can safely reduce hallucinations and delusions in people with Alzheimer's disease who also have psychosis. If you or your loved one has Alzheimer's and has been experiencing false beliefs or seeing/hearing things that aren't there for at least two months, this study may be an option.
Phoenix, ArizonaAges 55–90 - NCT07573982Recruiting
Ultrasound brain treatment for early memory loss
This study tests a special ultrasound treatment that may help clear harmful brain waste linked to Alzheimer's. You would receive the treatment in six short sessions, and the researchers will check your memory and brain health to see if it helps.
Stanford, CaliforniaAges 18 years+ - NCT06923007Recruiting
Vagus nerve stimulation for Alzheimer's disease
This trial tests if a nerve stimulation device can help people with mild to moderate Alzheimer's. It is for patients aged 50 to 80 who are on a stable medication.
BeijingAges 50–80 - NCT03503331RecruitingPhase 2
Alzheimer’s imaging add-on for research center patients
This study adds special brain scans (MRI and a PET scan) for people already enrolled in the UAB Alzheimer’s Disease Center research program. The scans are used to learn more about brain changes in Alzheimer’s, which may help researchers find better ways to measure and understand the disease.
Birmingham, AlabamaAges 50 years+ - NCT07827196Recruiting
Brain stimulation for behavior changes in early Alzheimer's
This study tests whether a gentle, non-invasive brain stimulation technique called transcranial random noise stimulation (tRNS) can help reduce troubling behavioral and psychological symptoms (like agitation or anxiety) in people with early Alzheimer's disease. Participants continue their usual medication and receive either real or fake stimulation to see if it improves symptoms.
Hefei, AnhuiAges 45–84 - NCT07422857RecruitingPhase 3
A PET scan for detecting signs of Alzheimer's
This trial uses a new type of PET scan to look for specific proteins in the brain that are linked to Alzheimer's disease. It will help doctors see how these proteins relate to cognitive decline and compare scans from people with normal thinking to those with memory problems.
Wuhan, HubeiAges 50 years+ - NCT07259499Recruiting
Predictors of emergency visits in frail older adults
This study looks at why frail older adults go to the emergency room. Researchers want to see if blood tests and brain scans can help predict who needs emergency care. Participation involves one interview and having had a recent brain scan and blood work.
Pisa, PisaAges 65 years+ - NCT07040904Recruiting
Mindfulness to help older Latino adults stay mentally sharp
This study tests whether mindfulness training can help older Latino adults stay sharp as they age. Researchers will measure changes in thinking skills and brain health.
St Louis, MissouriAges 65 years+ - NCT04360200Recruiting
Study of thinking changes in older adults
This trial looks at people over age 50 who have mild thinking or memory problems but do not have dementia by standard clinical criteria. It tests how these early changes are characterized and measured using exams such as blood tests and brain scans, which may help improve understanding and future care.
Guangzhou, GuangdongAges 50 years+ - NCT06375213Recruiting
Memory and thinking study for all ages
This study looks at how well people think and remember as they age. It includes healthy volunteers, people with mild memory issues, and those with dementia—both early- and late-onset.
Pathum Wan, BangkokAges 35 years+ - NCT07521384Enrolling by invitation
Real-World Study of Intranasal Cell Therapy for Brain Injuries
This study follows people who receive intranasal stem cell or exosome therapy (tiny packages from special cells) for brain or neurological conditions like stroke, brain injury, or cerebral palsy. Researchers track how well the treatment works by measuring inflammation markers in the blood and monitoring clinical improvements over time.
Monterrey, Nuevo LeónAges 4–80 - NCT07120347Recruiting
Remote sensors to study daily activities in older adults with mild memory loss
This study uses remote sensors (like motion detectors) to see how older adults with mild memory or thinking problems go about their daily lives. It may help researchers learn how to better support people with early dementia.
Columbia, MissouriAges 50 years+ - NCT06821568Recruiting
Home brain stimulation for memory and walking concerns
This study tests if a gentle brain-stimulation device used at home can help older adults who have both memory worries and slower walking. A study partner will help you use the device.
Roslindale, MassachusettsAges 65–90 - NCT06112860Recruiting
Over-the-counter hearing aids for memory loss study
This trial tests whether over-the-counter hearing aids can help people with mild memory loss (mild cognitive impairment or mild dementia) who also have hearing loss. You and a communication partner will participate together to see if improving hearing can also help with thinking and communication.
Evanston, IllinoisAges 60–90 - NCT04906863Recruiting
Genetic study for early dementia in adults and families
This trial studies genes to better understand why some people develop dementia and memory problems earlier in life. It may help researchers find clearer causes and improve future testing and treatments for families affected by dementia.
New York, New YorkAges 35 years+ - NCT04579120Recruiting
Brain scan study in healthy aging or early Alzheimer’s
This study uses brain imaging to understand changes in the brain during normal aging and early Alzheimer’s disease (AD). It may help researchers spot early brain changes and evaluate how well imaging measures those changes.
St Louis, MissouriAges 18 years+ - NCT06448403Recruiting
Alzheimer's assessment study with brain scans
This study uses brain scans (MRI and EEG) to better understand Alzheimer's disease. It compares people with MCI or Alzheimer's to healthy volunteers to see how the disease affects the brain.
Trondheim, TrønderlagAges 65 years+ - NCT06313853Recruiting
Communication support for older adults with dementia and cancer
This study tests a communication coaching session to help older adults with both dementia and cancer talk with their family and doctors about treatment decisions. The goal is to make sure your wishes and needs are heard.
Rochester, New YorkAges 65 years+ - NCT07205003Recruiting
Artery stiffness test for memory disorders
This study looks at how the stiffness of your carotid artery (the main artery in your neck) relates to memory problems. It involves a brain MRI that you may already have planned, and results could help doctors better understand certain types of dementia.
RouenAges 70 years+ - NCT07249918Recruiting
Wearable devices for dementia care in rural Taiwan
This trial tests if wearable devices can help monitor and improve behavioral symptoms like agitation, depression, or sleep problems in people with Alzheimer's or mild cognitive impairment. It also involves their caregivers.
Beigang, YunlinAges Any age - NCT03809351RecruitingPhase 1
Brain tau scan add-on for people in the UAB Alzheimer studies
This trial tests an added brain imaging scan that looks for “tau” protein in people already enrolled in the UAB Alzheimer research studies. Results may help researchers better understand Alzheimer’s disease and improve future diagnosis.
Birmingham, AlabamaAges 50 years+
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Common questions
- Are there clinical trials for alzheimer's disease dementia?
- Yes. Clin2 currently lists 471 recruiting alzheimer's disease dementia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alzheimer's disease dementia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alzheimer's disease dementia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.