Clinical trials
Alzheimer's Disease Dementia clinical trials
Below are recruiting alzheimer's disease dementia clinical trials, each written for real people, not researchers. We’re tracking 459 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03851523Recruiting
Tracking memory changes in people with early Alzheimer’s symptoms
This study follows people over time to better understand how memory and thinking complaints progress in early Alzheimer’s disease (from “subjective cognitive decline” to mild cognitive problems). It may help researchers understand who is likely to decline and how symptoms change, which could support future treatments.
Barcelona, CataloniaAges 45 years+ - NCT04570085RecruitingPhase 3
Caffeine treatment to improve thinking in Alzheimer’s disease
This trial tests whether changing caffeine intake can improve thinking and brain function in people with Alzheimer’s disease. You may qualify if you can follow a low-caffeine diet and have stable Alzheimer’s treatment and sleep/heart conditions.
AmiensAges 50 years+ - NCT04575337Recruiting
Biomarker study to help detect Alzheimer’s early
This study looks for brain/biological “signals” (biomarkers) that may identify Alzheimer’s disease earlier, including stages before clear symptoms. You may be followed for about 5 years, with repeated memory and thinking testing to see how these signs relate to future diagnosis.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04661280RecruitingPhase 3
Donepezil compared with non-drug care for Alzheimer’s
This trial compares donepezil (a medicine for Alzheimer’s symptoms) against a non-drug treatment plan. It aims to see which approach helps people with Alzheimer’s who still have measurable thinking ability and specific Alzheimer’s test results.
ParisAges 50 years+ - NCT04902703RecruitingPhase 2
GM-CSF drug trial for mild to moderate Alzheimer’s disease
This Phase 2 study tests whether sargramostim (a GM-CSF related medicine) is safe and can slow or improve Alzheimer’s symptoms. You might be a good fit if you have mild or moderate Alzheimer’s, positive amyloid testing, and can complete frequent visits with a close caregiver who knows you well.
Aurora, ColoradoAges 60–85 - NCT05295615Recruiting
Pulsed magnetic treatment for mild to moderate Alzheimer’s
This trial tests whether a pulsed electromagnetic field (a non-drug device that uses magnetic pulses) can help people with mild to moderate Alzheimer’s. Participants typically stay on stable Alzheimer’s medicines and follow daily home treatments during the study.
Hackensack, New JerseyAges 50–100 - NCT05413655RecruitingPhase 2
Oral drug for mild Alzheimer’s disease symptoms
This Phase 2 trial tests an oral medicine (EX039) to see if it can help people with mild Alzheimer’s disease. It focuses on slowing or improving thinking and memory problems over time.
TaipeiAges 50–80 - NCT05561205Recruiting
Brain stimulation to treat persistent apathy
This trial tests a noninvasive brain stimulation treatment (called rTMS) to help people who have had ongoing apathy (lack of motivation/interest) for at least a month. You might benefit if your apathy is persistent, your other symptoms are stable, and you meet the safety and medication rules.
Toronto, OntarioAges Any age - NCT05592366Recruiting
Testing a hospital tool for unpaid dementia caregivers
This study is testing a care-partner support tool for people who provide unpaid care to a hospitalized adult loved one or partner with dementia-related needs. It may help caregivers and hospitals communicate and coordinate better during a hospital stay.
Madison, WisconsinAges 18 years+ - NCT05661084Recruiting
Non-surgery brain stimulation for dementia thinking and movement
This study tests whether a non-invasive brain stimulation device (tES) can improve thinking and movement problems in people with dementia. You (and your caregiver, if needed) will be asked to follow the study plan and attend visits so researchers can measure results and safety.
Boston, MassachusettsAges 55 years+ - NCT05667649RecruitingPhase 1
Stem cells injected in brain for mild to moderate Alzheimer’s
This Phase 1 study tests whether injecting your own (autologous) activated fat-derived stem cells into the brain is safe and potentially helpful for mild to moderate Alzheimer’s disease. The goal is to see how the treatment affects the brain and symptoms, using cells made from your own donated fat tissue.
Newport Beach, CaliforniaAges 45–80 - NCT05748613Recruiting
Anxiety-focused skills training for people with Alzheimer’s
This study tests a treatment aimed at reducing anxiety in people who have Alzheimer’s disease or related memory problems. It also involves a support partner, and the goal is to see whether the program can lower anxiety and stress day-to-day.
Tallahassee, FloridaAges 60 years+ - NCT05801380Recruiting
Tracking how well a medicine works in Alzheimer’s patients
This study looks at how effective a treatment is in people newly diagnosed with mild to moderate Alzheimer’s disease. It also involves health and medication history checks and likely stool (fecal) sample collection to monitor effects.
Manila, National Capital RegionAges 65 years+ - NCT06052163RecruitingPhase 2
Testing bumetanide for early Alzheimer's disease
This study tests whether a water pill called bumetanide can help people with early Alzheimer's disease. It involves taking the study drug, having MRI scans, and doing memory tests to see if it slows down symptoms.
Stanford, CaliforniaAges 50–85 - NCT06099587Recruiting
Brain scan study for early Alzheimer's memory changes
This study uses a special MRI scan to look at the brain's memory center in people with early memory concerns. It aims to better understand changes that happen in the very early stages of Alzheimer's disease.
RennesAges 50–80 - NCT06297590RecruitingPhase 1
First human study of a new Alzheimer's drug
This study tests an experimental drug (LY3954068) for people with early Alzheimer's disease. It aims to see if the drug is safe and may slow memory loss. You'll need a PET scan to measure tau protein in the brain and have a study partner who can help attend appointments.
Maitland, FloridaAges 50–85 - NCT06385106Recruiting
Brain stimulation for memory loss in Alzheimer's
This study tests if repetitive transcranial magnetic stimulation (a non-invasive brain stimulation technique) can help improve memory and thinking in people with Alzheimer's disease. It may be an option if you are between 55 and 80, right-handed, and have a confirmed diagnosis of Alzheimer's.
Hangzhou, ZhejiangAges 55–80 - NCT06442852Recruiting
Blood microRNA linked to Alzheimer's risk and severity
This study looks for tiny molecules (miRNAs) in your blood that might be linked to Alzheimer's disease risk and severity. It compares people with Alzheimer's to healthy volunteers to find potential early warning signs.
Wuhan, HubeiAges 65 years+ - NCT06535308RecruitingPhase 1
Testing a new Alzheimer's drug for moderate disease
This study tests a new drug (BnH-015B) for people with moderate Alzheimer's disease. It also includes a small group of healthy young men for comparison. The goal is to see if the drug is safe and how it works in the body.
Seoul, Jongno-guAges 19–45 - NCT06566170Recruiting
Donanemab for early Alzheimer's: a real-world study
This study compares donanemab plus usual care to usual care alone for people with early Alzheimer's symptoms, to see how well donanemab works in everyday life. You may be able to join if you have early memory or thinking problems and have a brain scan or blood test showing Alzheimer's-related changes.
Huntsville, AlabamaAges 60 years+ - NCT06567431Recruiting
Blood and tears in alzheimer's disease
This study looks at different fluids from the body, like blood and tears, to find better ways to diagnose and track alzheimer's and related dementias. It compares people with these conditions to healthy volunteers to see what biological markers differ.
CopenhagenAges 30 years+ - NCT06582706RecruitingPhase 1/Phase 2
Vitamin B3 (niacin) for Alzheimer's disease
This study tests if nicotinic acid (a form of vitamin B3) can help people with mild to moderate Alzheimer's disease. It involves taking a daily pill, having a lumbar puncture, and regular check-ups to see if the vitamin improves thinking and memory.
Indianapolis, IndianaAges 60–85 - NCT06611878Recruiting
Music training for Alzheimer's patients at home
This trial tests whether intensive music training can help memory in people with Alzheimer's disease who live at home and are not musicians.
Buenos AiresAges 65 years+ - NCT06678100Recruiting
Swallowing study for adults with Alzheimer's
This study looks at swallowing problems in people with Alzheimer's disease compared to healthy older adults. If you have Alzheimer's, you'll have a swallowing test and your caregiver will answer questions about your daily life.
Nashville, TennesseeAges 60 years+
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Common questions
- Are there clinical trials for alzheimer's disease dementia?
- Yes. Clin2 currently lists 459 recruiting alzheimer's disease dementia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alzheimer's disease dementia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alzheimer's disease dementia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.