Clinical trials
Alzheimer’s disease clinical trials
A progressive brain disorder that affects memory and thinking. We’re tracking 601 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06817902Enrolling by invitation
TMS for Early Alzheimer's Disease Pilot
This trial tests whether transcranial magnetic stimulation (TMS), a noninvasive brain treatment, can help people with early Alzheimer's or mild cognitive impairment. It aims to see if the treatment is safe and effective for slowing memory decline.
Saint Paul, MinnesotaAges 40–90 - NCT06821568Recruiting
Home brain stimulation for memory and walking concerns
This study tests if a gentle brain-stimulation device used at home can help older adults who have both memory worries and slower walking. A study partner will help you use the device.
Roslindale, MassachusettsAges 65–90 - NCT05710549Recruiting
Brain study of autobiographical memory using brain stimulation
This study looks at how the brain supports remembering your own past experiences. It tests brain mechanisms using brain scanning (MRI) and noninvasive brain stimulation to see how these memory processes work.
Geneva, Canton of GenevaAges 18–85 - NCT06809725Enrolling by invitation
Study of a headband device for cognitive health check
This study tests a new way to check cognitive (thinking and memory) health using a simple headband that measures electrical signals on your scalp. It is looking for people 65 to 90 years old, with or without memory concerns, and a family member or friend who can also take part.
Miami, FloridaAges 65–90 - NCT06492109Recruiting
Blood study on sleep loss
This study looks at blood samples to understand how sleep loss affects the body. It may help find new ways to diagnose or treat sleep problems.
Hangzhou, ZhejiangAges 18–80 - NCT06728436Recruiting
Text message support for Latino caregivers of relatives with dementia
This study tests if text messages can help Latino caregivers feel less stressed or depressed while caring for a family member with Alzheimer's or related dementia. You may join if you provide hands-on care and feel down or overwhelmed.
Fairway, KansasAges 18–100 - NCT06723015Enrolling by invitationPhase 2
Tau PET in anti-amyloid therapy for Alzheimer's
This study uses brain scans to see how anti-amyloid treatments affect tau protein buildup in people with early Alzheimer's. If you have mild cognitive impairment or mild Alzheimer's, you may be eligible to help understand how these treatments work.
Rochester, MinnesotaAges 50–90 - NCT06722352Recruiting
Palliative care education for dementia in assisted living
This study trains staff in assisted living facilities to better support residents with dementia and their families in planning future care. It focuses on helping families talk about advance care planning (decisions about future medical care) with the care team.
Tampa, FloridaAges 21 years+ - NCT04134923Recruiting
Brain PET scan study using a blood-flow and plaque tracer
This study uses PET/CT/MRI imaging to look for brain “imaging biomarkers” in people across the Alzheimer’s disease range. It may help researchers better understand how Alzheimer’s changes the brain over time and improve future treatments.
St Louis, MissouriAges 18 years+ - NCT06669546Recruiting
Quiet sounds during deep sleep for memory in older adults
This study tests whether playing a soft, silent sound (or no sound) during deep sleep can improve memory, brain activity, and blood markers. It is for older adults (60-85) who have mild memory issues but are otherwise healthy.
BernAges 60–85 - NCT06618872Recruiting
Comparing tau and amyloid PET scans for memory problems
This study compares two types of brain PET scans (tau and amyloid) to see which one better helps diagnose memory problems. You may be eligible if you have mild cognitive impairment or mild dementia and your doctor has already ordered an amyloid PET scan.
Geneva, Canton of GenevaAges 50–85 - NCT06547099Recruiting
Understanding new blood markers in memory loss and dementia
This study is looking for older adults (60+) to help researchers better understand how to detect and track memory changes and dementia. Participants will provide blood samples and other health information over time to identify new markers that might help with early diagnosis.
St Louis, MissouriAges 60 years+ - NCT06496425Recruiting
Exercise for protecting memory in older adults
This study tests whether a 12-month exercise program can help protect memory and thinking skills in older adults who have noticed changes in their memory. You would be asked to exercise at home and attend some group classes.
Atlanta, GeorgiaAges 65 years+ - NCT06501495Recruiting
Brain waves and memory in aging and Alzheimer's
This study looks at how brain waves (EEG) change during normal aging and early Alzheimer's disease. It compares three groups: people with early-stage Alzheimer's, healthy older adults, and healthy young adults. The goal is to understand how memory and thinking problems relate to slow brain wave activity.
ParisAges 18–85 - NCT06467539RecruitingPhase 2
New combination treatment for early Alzheimer's or memory loss
This trial tests a new combination treatment (DAOIB and an antioxidant) for people with early Alzheimer's or mild cognitive impairment. It aims to see if the treatment can help slow or improve memory and thinking problems.
Kaohsiung CityAges 50–90 - NCT03761381Recruiting
Eye scan study for mild Alzheimer’s and memory changes
This study uses detailed eye imaging (an eye scan) to look for signs related to probable Alzheimer’s disease and mild dementia. It may help researchers understand whether eye scans can reflect brain changes and improve detection.
Portland, OregonAges 55 years+ - NCT06403345Recruiting
Green activity program for memory challenges
This study tests a green activity program for people with memory challenges. You and a friend or family member will take part in outdoor activities to see if they help with thinking and well-being.
Bloomington, IndianaAges 45 years+ - NCT06410157Recruiting
Mindfulness for heart-brain health in adults 50-70
This study tests whether a daily mindfulness practice can help older adults improve how their heart and brain work together. You will do breathing exercises at home and come to USC twice for check-ups, including blood and urine tests and an MRI.
Los Angeles, CaliforniaAges 50–70 - NCT05892952Recruiting
Scottish long-term study of aging and thinking
This study follows adults aged 50 and older over time to understand how thinking and memory change. You may help researchers learn what influences healthy aging and cognitive health.
Edinburgh, LothianAges 50–120 - NCT06298474Recruiting
BRAIN App for dementia support
This study is testing a new app (BRAIN App) designed to help people with dementia stay connected and engaged. Researchers want to see if the app can be useful for older adults who can still communicate and have not had a recent fast decline in health.
Winchester, MassachusettsAges 65 years+ - NCT06285448Enrolling by invitation
Lecanemab registry and outcome study
This study looks at how well lecanemab (a new Alzheimer's treatment) works in real-world clinics. It also tracks how patients and their care partners do over time. If you are already getting or eligible for lecanemab, you might join with your care partner.
Saint Paul, MinnesotaAges 18 years+ - NCT06168604Recruiting
Pain communication toolkit for dementia caregivers
This trial tests a toolkit to help caregivers of adults with dementia and chronic pain better identify and communicate about their loved one's pain. You and the person you care for may join if you meet the listed requirements.
New York, New YorkAges 21 years+ - NCT06174038Recruiting
Hearing aids for memory and hearing loss study
This study tests whether hearing aids can help people with both hearing loss and early memory problems. It lasts for a period of time, and you will be asked to wear hearing aids daily.
New York, New YorkAges 55–75 - NCT06121544Recruiting
Pre-Alzheimer's Study: Find Early Brain Changes
This study is looking for healthy volunteers to help detect the very earliest signs of Alzheimer's disease—before memory loss starts. You will have tests like memory checks, blood draws, brain scans, and a spinal tap to look for Alzheimer's-related changes.
MalmöAges 50–80
Hear when a new Alzheimer’s disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for alzheimer’s disease?
- Yes. Clin2 currently lists 601 recruiting alzheimer’s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alzheimer’s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alzheimer’s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.