Clinical trials
Ankle Fractures clinical trials
Below are recruiting ankle fractures clinical trials, each written for real people, not researchers. We’re tracking 32 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06709365Recruiting
Comparing two surgeries for complex ankle breaks in older adults
This trial tests two ways to fix complicated ankle and lower leg fractures in people over 65. It compares using a nail through the heel versus plates and screws to see which helps you heal and move better.
SohagAges 1–2 - NCT06518265Recruiting
Locked nail surgery for high-risk ankle fractures
This study looks at how well a special locking nail works for ankle fractures in patients with skin problems or injuries that make standard surgery risky. It aims to find out who benefits most from this less invasive method.
La TroncheAges 18–100 - NCT03966027Recruiting
Early vs late weight bearing after ankle surgery in diabetes
This trial compares two rehabilitation plans after ankle surgery: starting weight bearing sooner versus later. It may help people with diabetes heal safely and reduce complications related to healing and foot sensation.
Columbia, MissouriAges 18 years+ - NCT05131321Recruiting
Testing a frailty-focused plan for serious ankle fractures
This trial studies how best to manage serious ankle or tibia-pilon fractures in older adults who may be frail or have other major health problems. The goal is to improve care decisions and outcomes after injury, especially in people more likely to have complications.
London, OntarioAges 40 years+ - NCT05280639Recruiting
Simpler rehab plan after ankle or tibial plafond fracture
This trial tests whether a simpler “at-home” rehabilitation plan after ankle or lower-leg bone (tibial plafond) fractures works as well as standard care. It may help you recover strength and walking function with less clinic time.
Charlottesville, VirginiaAges 18–65 - NCT05413707Recruiting
CT-measured ankle fracture study for specific break pattern
This study looks at adults with a specific type of ankle fracture involving the back part of the ankle bone (posterior malleolus) plus a certain side fracture. It uses CT scan measurements to guide how the fracture is classified and studied, and it requires you to be willing and able to follow study instructions.
Bergen, VestlandAges 18–65 - NCT05445960Recruiting
Tourniquet use during ankle surgery and recovery outcomes
This study looks at whether using a tourniquet during ankle fracture surgery affects healing, leg movement, and patient-reported recovery. It may help doctors choose the safest, most comfortable approach for surgery.
Portland, OregonAges 18–89 - NCT05555459Recruiting
Testing a screw system for foot and ankle surgery
This study checks how safe and well an “Inion CompressOn” screw system works during foot and ankle operations. It may help patients by improving how surgeons fix bones while also collecting safety and recovery information.
TampereAges 18 years+ - NCT05765929Recruiting
X-ray tests for deciding how to treat certain ankle fractures
This study uses special standing (weightbearing) ankle X-rays to see whether your ankle fracture is stable, to help guide treatment decisions. It may help doctors choose safer, more appropriate care for specific ankle fracture types.
Sarpsborg, Østfold fylkeAges 18–75 - NCT06085586Recruiting
Fibulink implant for ankle fracture with torn ligament, early weight bearing
This trial tests a new surgical implant system (Fibulink) for repairing a torn ligament between the shin bones (syndesmosis) along with an ankle fracture. The goal is to allow you to put weight on your foot earlier than usual after surgery.
Brooklyn, New YorkAges 22 years+ - NCT06568276Recruiting
Repairing the deltoid ligament in unstable ankle fractures
This study tests whether repairing the deltoid ligament on the inner side of the ankle helps people heal better after an unstable ankle fracture. If you have a certain type of break (Weber B) that shows widening on x-ray, you may be able to join.
Grålum, Postbox 300Ages 18–65 - NCT07163091Recruiting
Bracing for ankle fracture recovery
This study tests whether wearing a brace after an ankle fracture helps healing better than standard care. It is for adults who have been treated for an ankle fracture and can already put weight on their foot.
AabenraaAges 18 years+ - NCT07173088Recruiting
Ankle exercise program after fracture surgery
This study tests a new exercise program called the Ankle Muscle Power (AMP) program to help people get back to full duty after an ankle fracture surgery. It aims to see if this program is effective and practical for recovery.
Lexington, KentuckyAges 18–50 - NCT07473947Recruiting
Study of bioabsorbable screws for ankle, knee, and elbow fractures in kids
This trial tests a special screw that dissolves over time to fix broken bones in the ankle, knee, or elbow. It may help children and teens avoid a second surgery to remove metal screws.
TurkuAges Up to 17 years - NCT03696199RecruitingPhase 4
Test better pain control after ankle fracture surgery
This trial studies a pain-control approach (a kind of nerve block) to see if it can reduce pain after surgery for certain ankle fractures. It may help you feel more comfortable while your ankle heals after an operation.
Burlington, MassachusettsAges 18–89 - NCT06863688Enrolling by invitation
Ankle fracture surgery with tourniquet study
This trial compares tourniquet use during ankle fracture surgery. It looks at outcomes for patients with a simple (closed) ankle fracture caused by a ground-level fall who are having metal plates and screws placed.
Iowa City, IowaAges 18–65 - NCT06949826RecruitingPhase 4
Buprenorphine for pain after ankle fracture surgery
This trial tests if buprenorphine, a non-opioid pain medicine, works well for people who have not used opioids before. After ankle fracture surgery, you would get buprenorphine instead of stronger opioids to see if it controls pain just as well with fewer side effects.
St Louis, MissouriAges 18 years+ - NCT07620015Recruiting
Turkish Ankle Fracture Recovery Measure Validation Study
This study is testing a questionnaire (in Turkish) that measures how well people recover after ankle fractures. Researchers want to make sure the questionnaire accurately reflects your recovery progress, whether you had surgery or wore a cast.
KyreniaAges 18 years+ - NCT07481266Recruiting
One window vs. two: better ankle fracture surgery?
This study compares two ways to fix a broken ankle involving the back and side bones. One method uses a single incision, the other uses two. It aims to see which gives better results.
AnkaraAges 18–65 - NCT07221019RecruitingPhase 4
Pain relief after leg injury: single shot vs. continuous numbing
This study compares two ways to manage pain after a leg injury: a single injection of a long-lasting numbing medicine (Exparel) versus a small tube that delivers numbing medicine for a few days (catheter). It is for people who have not used strong painkillers before and have a closed leg fracture.
Washington D.C., District of ColumbiaAges 18 years+ - NCT02664337Enrolling by invitation
Study of what people prefer in joint and fracture treatments
This study asks patients (or parents/caregivers, for children’s injuries) about their preferences for different treatment options for certain joint and fracture problems. It may help clinicians choose care plans that match what patients value.
Durham, North CarolinaAges 18–85 - NCT07539922Recruiting
Double Screw Surgery for Ankle Fractures That Haven't Healed
This trial tests a surgical technique using two screws to fix ankle fractures (specifically on the outer ankle bone) that haven't healed properly after six months or more. The goal is to help the bone heal and reduce pain and disability.
Sohag, Sohag GovernorateAges 18–65 - NCT06078371Recruiting
Opioid-free pain treatment after broken bone surgery
This study compares standard pain treatment using opioids to a new opioid-free pain block for people who had surgery for broken bones. The goal is to find safer, non-addictive ways to manage pain after trauma.
Kansas City, KansasAges 18 years+ - NCT06370325Recruiting
Electrical stimulation after ankle fracture surgery
This study tests whether a gentle electrical stimulation device placed on the skin around the ankle can help recovery after ankle fracture surgery. It may reduce pain, swelling, and healing time.
New York, New YorkAges 18–70
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Common questions
- Are there clinical trials for ankle fractures?
- Yes. Clin2 currently lists 32 recruiting ankle fractures studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ankle fractures trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ankle fractures trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.