Clinical trials
Ankle Sprains clinical trials
Below are recruiting ankle sprains clinical trials, each written for real people, not researchers. We’re tracking 28 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07760233Recruiting
Balance training with eye exercises for unstable ankles
This study tests whether adding eye exercises to standard balance training helps amateur athletes with chronic ankle instability. It aims to improve ankle stability and reduce the feeling of the ankle 'giving way'.
Istanbul, TurkeyAges 18–35 - NCT07449078Recruiting
Cognitive functional therapy for chronic ankle sprain
This trial tests a type of talk therapy that teaches you new ways to move and think about your ankle. It may help people who have ongoing pain or instability from an old sprain.
Istanbul, AtaşehirAges 18–65 - NCT07728526Recruiting
Eye exercises plus balance training for ankle instability
This study tests whether adding specific eye-movement exercises to standard balance training helps athletes with long-term ankle instability. It may improve your ankle control and reduce the feeling of your ankle giving way.
IstanbulAges 18–35 - NCT07726810Recruiting
Exercises with music beats for ankle sprain recovery
This study tests if adding rhythmic music or sounds to special balance and stability exercises helps people recover better from a mild to moderate lateral ankle sprain (an injury to the outer side of the ankle). It may be a good option if your ankle sprain happened 2 to 8 weeks ago and you haven't had ankle surgery before.
Lahore, Punjab ProvinceAges 18–30 - NCT04846712Recruiting
Ultrasound to check how severe a new ankle sprain is
This trial studies whether an ultrasound scan can help doctors judge how severe a first-time ankle sprain is. It may help guide treatment and follow-up for people whose sprain affects work or sports.
Saint-EtienneAges 18–60 - NCT06645262Recruiting
Ankle sprain rehab study
This study looks at therapies for a first-time mild ankle sprain (Grade I). It may help you recover faster and avoid future problems.
MostarAges 4 months+ - NCT06854016Recruiting
Laser therapy for recent ankle sprain
This trial tests if a special laser (LightForce®) can help reduce pain from a lateral ankle sprain that happened within the last 72 hours. It may be a good option if you have moderate to severe pain and want a non-drug treatment.
Cassano d'Adda, MilanoAges 18 years+ - NCT07025733Recruiting
Smart socks for ankle sprains study
This trial tests special socks with tiny sensors that may track your ankle healing after a sprain or minor fracture. Researchers want to see if these socks give useful information to help you recover.
Aurora, ColoradoAges 18–70 - NCT07190599Recruiting
Electrical stimulation with stretching for ankle sprain rehab
This trial tests whether combining electrical muscle stimulation with a specific stretching technique helps adults recover from an ankle sprain. It may improve ankle strength and movement.
Kaohsiung City, No. 151, Jinxue Road, Daliao DistrictAges 18–30 - NCT07606534Recruiting
Ankle, Hip, or Combined Exercises for Chronic Ankle Instability
This study compares three different exercise programs to strengthen your ankle and improve stability. If you have a history of ankle sprains with ongoing instability problems, this trial tests which type of strengthening works best to prevent future injuries and improve your ability to do sports.
LiègeAges 18–35 - NCT06868316Recruiting
Sound-guided walking training for chronic ankle instability
This study tests whether using sound cues while walking can improve balance and ankle stability in people with chronic ankle instability. You may be eligible if you have had repeated ankle sprains and a feeling of your ankle "giving way" in the last 6 months.
Lexington, KentuckyAges 18–45 - NCT06898554Recruiting
Understanding Ankle Control in Athletes with Unstable Ankles
This trial studies how your brain and spinal cord control your ankle if you have chronic ankle instability (a long-term wobbly ankle). It is for athletes between 18 and 25 who play team sports and have had repeated ankle sprains.
IstanbulAges 18–25 - NCT07054892Recruiting
Ankle sprain: how it affects your daily life
This study checks how an ankle sprain affects your daily life and well-being. If you came to the Saint-Brieuc emergency room with a twisted or sprained ankle (no broken bone or need for surgery), researchers will ask you about your recovery and quality of life over time.
Saint-BrieucAges 18 years+ - NCT06499935Recruiting
Taping for ankle instability in athletes
This study tests whether taping can change how pressure is distributed on your foot while playing sports. It may help if you have long-term ankle instability from past sprains.
BeirutAges 18–28 - NCT06568276Recruiting
Repairing the deltoid ligament in unstable ankle fractures
This study tests whether repairing the deltoid ligament on the inner side of the ankle helps people heal better after an unstable ankle fracture. If you have a certain type of break (Weber B) that shows widening on x-ray, you may be able to join.
Grålum, Postbox 300Ages 18–65 - NCT04095598Recruiting
CT scan with stress tests for unstable ankle ligaments
This study tests whether a special CT scan with gentle stress maneuvers can better find ankle ligament injury (syndesmotic instability) after a sprain. If you had a recent ankle sprain and exam suggests this specific injury, the scan may help guide the right treatment.
São Paulo, São PauloAges 18 years+ - NCT04999904Recruiting
Balance training on uneven treadmill for unstable ankles
This study tests a special balance and movement training program on an uneven treadmill to improve ankle stability. It may help people whose ankles “give way” or keep getting sprained, but it requires specific timing after an ankle sprain and the ability to attend sessions for about 6 weeks.
Oceanside, CaliforniaAges 18–49 - NCT03643926Recruiting
Arthroscopic vs open surgery for ankle instability
This trial compares two surgical approaches to treat ongoing ankle “giving way” or instability. It aims to find which method works better for people whose ankle instability has lasted at least several months.
Belo Horizonte, Minas GeraisAges 18–65 - NCT03663361Recruiting
Ankle rehab plan for a new ankle sprain
This trial studies a rehabilitation approach to improve outcomes for a fresh ankle sprain (Grade I–III) started within the first 72 hours. It may help you recover faster and better, but it also has safety exclusions related to seizures and certain implanted devices.
Lexington, KentuckyAges 18–44 - NCT05785533Recruiting
Mobile app for recovery after recent ankle sprains
This trial tests whether a smartphone “recovery guidance” app can help children and young adults heal after a recent ankle inversion injury. It may help with home recovery steps and decision-making during the first days after injury.
London, OntarioAges 12–30 - NCT07145645RecruitingPhase 3
Comparing topical diclofenac to oral ibuprofen for pain from ankle or knee injuries in children
This study compares a topical gel (diclofenac) applied directly to the injury site versus an oral medication (ibuprofen) taken by mouth to see which works better for treating pain from ankle or knee injuries in children. It may offer a way to relieve pain without a pill.
Calgary, AlbertaAges 6–18 - NCT06631690Recruiting
ACL surgery and ankle joint function study
This study looks at how ACL reconstruction knee surgery might affect the mechanics of your ankle joint. It aims to understand if the surgery changes how your ankle moves and works, which could help improve rehabilitation.
CairoAges 15–45 - NCT07200271Recruiting
Surgery for chronic ankle instability: Broström vs allograft
This trial compares two surgical techniques to fix chronic ankle instability. It is for people with ongoing ankle weakness, multiple sprains, or loose ligaments who have not had ankle surgery before.
Valdemoro, MadridAges 18 years+ - NCT06182943Recruiting
Electroacupuncture for recent mild to moderate ankle sprains
This study tests whether a type of acupuncture with mild electrical current (electroacupuncture) can help heal a fresh, mild-to-moderate ankle sprain. You may be eligible if you sprained your ankle within the last 48 hours, have no broken bones, and do not have serious health issues.
Hangzhou, ZhejiangAges 18–60
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Common questions
- Are there clinical trials for ankle sprains?
- Yes. Clin2 currently lists 28 recruiting ankle sprains studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ankle sprains trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ankle sprains trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.