Clinical trials
Anxiety clinical trials
Ongoing, excessive worry or fear that interferes with daily life. We’re tracking 1,061 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05457465RecruitingPhase 2
Cannabidiol study for anxiety and depression in bipolar disorder
This Phase 2 study tests whether cannabidiol (CBD) can reduce anxiety and depressive symptoms in people with bipolar disorder. It may help if your mood symptoms are persistent and you’re already on stable bipolar medications.
Belmont, MassachusettsAges 18–65 - NCT05461092RecruitingEarly Phase 1
Nerve blocks to improve pain control after spinal fusion
This early-stage study tests whether a regional nerve block can improve pain control and recovery for older adults having elective lumbar spinal fusion. If you qualify, you may receive a special pain-control injection during surgery to reduce opioid needs and improve recovery comfort.
Iowa City, IowaAges 65 years+ - NCT05464888Recruiting
Animal-assisted therapy for kids’ dental visits
This study tests whether working with a trained animal can make dental checkups and cleanings easier for children ages 4 to 8. It may help reduce fear and improve how kids tolerate routine dental care.
Chapel Hill, North CarolinaAges 4–8 - NCT05472909Recruiting
Music during a specific type of hand surgery
This trial studies whether playing music during a “wide-awake” hand surgery helps comfort or experience during the procedure. You may be offered music while you’re awake and having local numbing medicine.
Madison, WisconsinAges 18 years+ - NCT05474846RecruitingPhase 2/Phase 3
Combination treatment to improve sleep in advanced cancer
This trial tests a combination approach to improve poor sleep in people with advanced cancer. If you qualify, you would answer sleep and symptom questions and may do a structured therapy (CBT) plus follow-up visits.
Houston, TexasAges 18 years+ - NCT05475600Recruiting
Biofeedback and relaxation for ICU patients with blood cancers
This trial tests whether guided biofeedback and relaxation techniques can help people with blood cancers while they are in the ICU. It may improve comfort and stress during critical illness, compared with standard care.
MetzAges 18–75 - NCT05485701Recruiting
Study of perinatal mental health in India
This study looks at mental health during pregnancy and after birth, and may help improve how these concerns are understood and assessed. You may be interviewed or asked to complete surveys across a few visits, depending on which part of the study you join.
Kangra, Himachal PradeshAges 18–45 - NCT05505188Recruiting
Predicting long-term pain after head and neck radiotherapy
This study looks for ways to predict and improve pain you may have months after radiotherapy for first head and neck cancer. It may help doctors better anticipate pain and support patients during recovery.
CaenAges 18 years+ - NCT05511909RecruitingPhase 2
Buspirone study for opioid withdrawal symptoms
This Phase 2 study tests whether buspirone can help reduce symptoms during opioid detox (withdrawal). You may be able to take part if you have opioid withdrawal and are planning medically supervised detox.
Baltimore, MarylandAges 18–75 - NCT05527509Recruiting
Study of risk and resilience in new RCMP cadets
This study follows people as they start RCMP Cadet Training to learn what factors affect “risk” and “resilience” (how well someone adapts under stress). It may help improve support for cadets during training.
Regina, SaskatchewanAges 19–57 - NCT05555875Recruiting
Study how people engage with digital mental health tools
This study looks at what helps (or prevents) people from using digital mental health programs. You may join if you have meaningful depression and/or anxiety symptoms and you can use a smartphone for the study apps.
Boston, MassachusettsAges 18–75 - NCT05558527Recruiting
Study of how relationships affect noticing threat cues
This study looks at how being in a stable romantic relationship changes how you notice and react to threat-related cues. It may help researchers understand factors that shape fear and alertness, which could guide future mental health treatments.
Reno, NevadaAges 18–65 - NCT05563805Recruiting
Virtual reality adventure training for movement and fitness
This study uses a virtual reality “adventure” game that gets you moving to train exercise skills and coordination. It’s designed for U.S. military veterans who can walk on their own and don’t have certain vision, balance, or medical limits.
Arlington, TexasAges 18–45 - NCT05569018Recruiting
Spanish blended group therapy for anxiety and depression symptoms
This study tests whether a group therapy program delivered in both online and in-person formats can reduce emotional symptoms like anxiety and depression. If you qualify, you may be assigned to receive this structured group treatment during the study period.
Castellon, CastellónAges 18 years+ - NCT05570812RecruitingPhase 2
Pregnenolone to improve depressed mood in people with HIV
This Phase 2 trial tests a brain-acting steroid called pregnenolone to help reduce depressed mood. It studies whether it can improve mood in adults with HIV who are already on HIV treatment and still have depression symptoms.
Boston, MassachusettsAges 18–85 - NCT05591937Recruiting
Online therapy and prevention support for eligible East LA students
This project offers online mental health prevention and therapy programs and short assessments for eligible students. It may help you access support in a convenient way if you meet the study’s student, coverage, and technology needs.
Los Angeles, CaliforniaAges 18–40 - NCT05603000Recruiting
Emotion-focused therapy for parents of anxious or struggling children
This study tests an emotion-focused family therapy program for parents of children (ages 7–15) who are dealing with anxiety, depression, or behavior challenges. It may help families improve how emotions are understood and managed through parent participation and home life support.
Guelph, OntarioAges 7–15 - NCT05648539Recruiting
Music therapy for mood and anxiety symptoms
This trial studies whether music therapy can improve symptoms of depression or anxiety. You may be invited if you have mild mood or anxiety symptoms on common screening questionnaires.
Nanjing, JiangsuAges 16–35 - NCT05651295Recruiting
Smartphone precision study to improve emotion regulation
This trial tests a precision approach delivered through a smartphone to better track and target how you manage strong emotions. It may help if you have ongoing difficulty regulating emotions day to day.
Columbus, OhioAges 18 years+ - NCT05656469Recruiting
Personalized psychiatry meds using gene test results
This study compares a personalized medication plan based on your genes versus standard dosing for people with depression, anxiety, or psychosis. It may help your clinician choose a safer or more effective dose or medicine by using pharmacogenomics (gene-informed prescribing).
Syracuse, New YorkAges 16–70 - NCT05674357Recruiting
Training therapists to help people with cancer distress
This trial trains therapists in evidence-based treatments to reduce distress related to cancer and cancer care. You may be able to join if you’re being treated or followed at MGH Cancer Center and your distress level is high.
Boston, MassachusettsAges 18 years+ - NCT05685368RecruitingPhase 1/Phase 2
Therapy groups to help teens cope with sickle cell
This trial tests a structured talk-therapy program called Acceptance and Commitment Therapy (ACT) for teens and young adults with sickle cell disease. It aims to help you manage tough thoughts and feelings and cope with day-to-day challenges over 6 weekly group sessions.
Los Angeles, CaliforniaAges 14–21 - NCT05699525Recruiting
Personalized app for cognitive behavioral therapy for young adults
This trial tests a mobile app that delivers personalized cognitive behavioral therapy (a structured talk-therapy approach that helps change unhelpful thoughts and behaviors). It may help reduce symptoms of anxiety, depression, or bipolar disorder for people who fit the study’s timing and safety requirements.
New York, New YorkAges 18–25 - NCT05710991Recruiting
Brief therapy for sleep trouble in early pregnancy
This trial compares two short approaches to help with insomnia (sleep difficulties) during early pregnancy: brief cognitive behavioral therapy or sleep hygiene tips. It may help improve how well you sleep without using new or changing medications.
Hamilton, OntarioAges 18–45
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Common questions
- Are there clinical trials for anxiety?
- Yes. Clin2 currently lists 1,061 recruiting anxiety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a anxiety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a anxiety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.