Clinical trials · Cleveland, OH
Aortic Stenosis clinical trials in Cleveland
We’re tracking 11 recruiting aortic stenosis studies with a site in or near Cleveland — including Phase 2/Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Cleveland
- NCT06780241Recruiting
Sex differences in valvular heart disease
This study uses special MRI scans to look at how valvular heart disease (like leaky or narrowed aortic valves) affects men and women differently. It aims to find unique biological patterns that could lead to better treatments.
Cleveland, OhioAges 18–90 - NCT05172960Recruiting
Study of a new heart valve for severe aortic stenosis
This trial tests a new version of a heart valve (SAPIEN X4) placed without open-heart surgery. It's for people with severe aortic stenosis who have symptoms like shortness of breath or chest pain.
Cleveland, OhioAges Any age - NCT07001800RecruitingPhase 2/Phase 3
Slowing aortic valve disease with ataciguat
This trial tests a new pill, ataciguat, to slow down the progression of moderate calcific aortic valve stenosis (a condition where your aortic valve stiffens). If you have moderate valve narrowing and meet the other criteria, participation could help find a way to delay needing surgery.
Cleveland, OhioAges 50 years+ - NCT06689839Recruiting
Testing a new filter to prevent stroke during heart valve replacement
This trial tests a new filter device designed to catch debris that might travel to the brain during a minimally invasive aortic valve replacement (TAVR). The goal is to see if it can help reduce the risk of stroke.
Cleveland, OhioAges 50 years+ - NCT05932615Enrolling by invitation
Testing a new transcatheter valve for aortic valve narrowing
This trial studies how safe and effective the NAVITOR valve is for treating narrowed aortic valves placed through a catheter (no open-heart surgery). It may be an option if you’re at intermediate-to-low surgical risk and meet heart ultrasound/CT measurements.
Cleveland, OhioAges 18 years+ - NCT05603026Recruiting
MRI study for people getting a valve replacement
This study uses MRI (a type of scan) in people who are scheduled for a catheter-based aortic valve replacement through the groin. It aims to see how well MRI can work for these patients and potentially improve care planning around the procedure.
Cleveland, OhioAges 18–105 - NCT06777368Recruiting
Redo TAVR for failed transcatheter aortic valves
This trial tests a second transcatheter aortic valve replacement (TAVR) procedure for patients whose first TAVR valve is failing. It focuses on structural problems inside the valve, not leakage around it.
Cleveland, OhioAges 18–105 - NCT03003299Recruiting
Valve replacement for failing aortic bioprosthetic valves
This trial studies a new “valve-in-valve” procedure to treat a failing aortic bioprosthetic valve. It may help people improve blood flow through the heart valve and reduce valve-related problems.
Cleveland, OhioAges Any age - NCT04126018Recruiting
MRI scan comparison for certain leaking or narrowed heart valves
This trial studies how well different MRI images can assess heart valve problems—like leaking (regurgitation) or narrowing (stenosis). It may help doctors get clearer information, especially in people who may not respond well to cardiac resynchronization therapy (CRT).
Cleveland, OhioAges 18–90 - NCT05172973Recruiting
New valve procedure for failing aortic bioprosthetic valves
This trial studies whether a new transcatheter aortic valve (SAPIEN X4) is safe and works well in people whose previously implanted aortic valve is now failing. It may help reduce valve symptoms in higher-surgery-risk patients who are not good candidates for open-heart valve replacement.
Cleveland, OhioAges Any age - NCT04634240Recruiting
Staged heart bypass plus TAVR versus TAVR alone
This study compares doing a staged coronary bypass (revascularization) along with a valve procedure (TAVR) versus doing TAVR and medical treatment alone. It aims to see which approach better helps people with both aortic valve narrowing and coronary artery disease.
Akron, OhioAges Any age
Hear when a new Aortic Stenosis trial opens near Cleveland, OH
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Aortic Stenosis trials in other cities
Where these studies are running near Cleveland
Institutions with a site for the recruiting aortic stenosis studies listed above.
- Cleveland Clinic · 8 studies
- University Hospitals Cleveland Medical Center · 2 studies
- Summa Health System - Akron Campus
What taking part in a aortic stenosis study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting aortic stenosis studies in Ohio.
Common questions
- Are there aortic stenosis clinical trials near Cleveland?
- Yes. We're currently tracking 11 recruiting aortic stenosis studies with a site near Cleveland, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a aortic stenosis study near Cleveland?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Cleveland to take part?
- Not necessarily. These studies have a site near Cleveland, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a aortic stenosis trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New aortic stenosis studies open near Cleveland regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.