Clinical trials
Aphasia clinical trials
Below are recruiting aphasia clinical trials, each written for real people, not researchers. We’re tracking 95 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03887481Recruiting
Brain stimulation study for a language-loss dementia subtype
This trial tests whether a painless form of brain stimulation can improve language and thinking skills in people with the logopenic variant of primary progressive aphasia (a dementia that affects language). You may receive brain stimulation along with repeated clinic visits to track changes over time.
Baltimore, MarylandAges 50–80 - NCT04142866Recruiting
Brain stimulation plus language practice for chronic aphasia
This study tests whether mild brain stimulation (tDCS) combined with language exercises can improve communication after a stroke. It also includes healthy volunteers to help compare brain and language task results.
New York, New YorkAges 21–80 - NCT04375722Recruiting
Brain stimulation study for language problems after stroke
This trial tests whether gentle, noninvasive brain stimulation (tACS) can improve speech and language (aphasia) after stroke. You may be asked to do language and thinking tests before and after the stimulation to see if it helps.
Milwaukee, WisconsinAges 18–85 - NCT04432883Recruiting
Brain stimulation to improve speech after stroke aphasia
This trial tests whether targeted mild brain stimulation (tDCS) can improve speech therapy results for people with long-lasting (chronic) aphasia after a stroke. It may help strengthen naming and communication when added to standard speech-language treatment.
Albuquerque, New MexicoAges 25–85 - NCT04433351Recruiting
Rehab training to improve speech after stroke in French speakers
This trial studies a sensory-and-movement training approach to help people relearn speech after stroke-related language difficulties. It may help if your type of post-stroke aphasia is mainly non-fluent and you can safely complete brain scans.
GrenobleAges 55–75 - NCT04682223Recruiting
Online speech therapy for people with stroke-related aphasia
This study tests whether telerehabilitation (therapy done by video/remote technology) can improve communication after a stroke caused aphasia. It may help you practice speech and understanding skills at home or from a convenient location.
Columbia, South CarolinaAges 21–80 - NCT04742894Recruiting
EEG and MRI study of speech problems after stroke
This study looks at brain activity during speech tasks to better understand why some people with aphasia have trouble coordinating speech. It compares people with long-term (chronic) left-stroke aphasia to healthy volunteers, using EEG and MRI.
Irvine, CaliforniaAges 21–75 - NCT04920318Recruiting
Study to improve language in primary progressive aphasia
This trial looks at ways to improve language abilities in people with primary progressive aphasia (a long-term brain condition that affects speech and language). It may help if your communication problems come from this condition and you can safely take part in the study activities, which likely involve language practice and MRI scanning.
Tucson, ArizonaAges 45–80 - NCT05194566Recruiting
Brain stimulation for long-term speech trouble after stroke
This study tests whether a form of brain stimulation can improve naming words in people who still have language problems (aphasia) more than 6 months after a stroke. It may help people find and say words more accurately during a naming task.
Chicago, IllinoisAges 18–80 - NCT05303649Recruiting
Theta burst brain stimulation for language problems after stroke
This study tests whether a type of brain stimulation guided by a brain scan (MRI) can improve speech and language (“aphasia”) after a stroke. It may help people who have trouble producing speech but can still understand others’ words.
Warsaw, Masovian VoivodeshipAges 18–75 - NCT05415501Recruiting
Sentence practice training for people with post-stroke aphasia
This study tests a training program designed to help people with aphasia—trouble making sentences—after a stroke. It may help improve sentence use and communication by practicing targeted sentence production skills.
West Lafayette, IndianaAges 21–85 - NCT05653440RecruitingPhase 2
Naming therapy training for chronic post-stroke aphasia
This Phase 2 trial studies a speech therapy approach that teaches people with aphasia how to name words, using different learning methods. You may be able to join if your language problem started after a stroke and has lasted more than 6 months.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05653466RecruitingPhase 2
Telehealth therapy schedule for stroke-related aphasia patients
This trial tests an approach that adjusts therapy scheduling for people with long-lasting (over 6 months) language problems after a stroke. It may help some patients by matching the therapy timing to what works best for them.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05730023Recruiting
Testing a new approach for primary progressive aphasia diagnosis
This study focuses on people with primary progressive aphasia (PPA), a condition that affects language over time. It tests a “multimodal” set of assessments and treatment planning, which may help your care team diagnose and support you more accurately.
Brescia, BSAges 40 years+ - NCT05907031Recruiting
Brain stimulation to improve language after left-stroke aphasia
This trial studies a specific brain-stimulation method to help improve speech and language problems (aphasia) after an ischemic stroke. You may qualify if your stroke affected the left side of the brain and your language testing shows moderate language difficulty.
Fuzhou, FujianAges 35–75 - NCT05957354Recruiting
Brain stimulation therapy for stroke-related language loss
This trial studies a targeted, non-surgical brain stimulation approach to improve aphasia (language problems) after a first stroke. It may help people regain better language skills by guiding stimulation to specific brain areas.
Jinan, ShandongAges 35–75 - NCT05957445Recruiting
Brain stimulation to improve speech after stroke aphasia
This trial tests a focused brain stimulation approach (cTBS) guided by a planning method (pBFS) to improve language problems after stroke. If you have new stroke-related aphasia, it may help your ability to understand and produce speech as you recover.
Baoding, HebeiAges 35–75 - NCT05969548Recruiting
Brain stimulation to improve stroke-related speech problems
This trial studies different doses of a targeted brain stimulation technique to treat aphasia (language problems) after a first stroke. If you qualify, the goal is to see whether the treatment can improve your ability to understand and speak.
Nanyang, HenanAges 35–75 - NCT05999318Recruiting
Brain stimulation for language recovery after stroke
This study tests a non-invasive brain stimulation method (using magnetic pulses) to help people recover language after a left-side stroke. If you have aphasia from a recent first stroke, this treatment might boost your recovery.
ChangchunAges 35–75 - NCT06048159Recruiting
Brain stimulation to improve memory after stroke-related aphasia
This study tests a safe, non-invasive brain stimulation called tACS to see if it can help improve short-term memory for sounds and words in people who have trouble speaking after a stroke. If you have aphasia from a left-brain stroke, this treatment might help your brain relearn how to remember and repeat what you hear.
Milwaukee, WisconsinAges 18 years+ - NCT06066710RecruitingEarly Phase 1
Propranolol for Primary Progressive Aphasia
This trial tests whether the drug propranolol, often used for high blood pressure, can help people with primary progressive aphasia (a condition that slowly affects language skills). You would take the drug and have MRI brain scans to see if it slows language decline.
Columbia, MissouriAges 50 years+ - NCT06092814Recruiting
Brain stimulation to boost language after stroke
This study tests whether a gentle electrical current (tACS) applied to the scalp can improve language abilities in people with aphasia after a stroke. Healthy volunteers are also needed as a comparison group.
Philadelphia, PennsylvaniaAges 18–85 - NCT06323330Recruiting
Music therapy for speech recovery after stroke
This study tests if music therapy can help people with speech problems after a stroke. It is designed for those who had a stroke within the past year and have trouble speaking fluently (non-fluent aphasia).
New Delhi, National Capital Territory of DelhiAges 18–99 - NCT06368323Recruiting
Choir singing for people with aphasia after stroke
This study tests if singing in a community choir can help people with aphasia (trouble speaking or understanding language) after a stroke. It focuses on those who have had a stroke at least 6 months ago and who speak English or French at home.
Tampa, FloridaAges 18 years+
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Common questions
- Are there clinical trials for aphasia?
- Yes. Clin2 currently lists 95 recruiting aphasia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a aphasia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a aphasia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.