Clin2
NCT07800871Possibly a fitRecruiting

FT839 cell therapy for autoimmune diseases

ANCA-Associated Vasculitis (AAV)Idiopathic Inflammatory Myositis (IIM)Rheumatoid Arthritis (RA)Systemic Lupus Erythematosus (SLE)Systemic Sclerosis (SSc)

Part of Bones, joints & muscles, Brain & nervous system, Heart & circulation, Immune system & allergy, Skin clinical trials.

This trial tests a new cell therapy (FT839) designed to target and reset the immune system's B cells to help treat moderate to severe autoimmune diseases that haven't improved with standard treatments. It's an early-phase study, so the main goals are to see if it's safe and if it helps control the disease.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
446 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You must be between 18 and 70 years old.
  • You must have a moderate or severe autoimmune disease (such as lupus, rheumatoid arthritis, or vasculitis) that has not responded to at least two prior treatments.
  • Your major organs (heart, lungs, liver, kidneys) must be functioning reasonably well to handle the treatment.
  • You cannot be pregnant, nursing, or have a history of certain infections, cancers, or organ transplants.
  • You must not have received anti-CD19 or anti-CD20 therapies within the last 6 months.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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