Clinical trials
Arthritis clinical trials
Below are recruiting arthritis clinical trials, each written for real people, not researchers. We’re tracking 558 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07704580RecruitingPhase 1/Phase 2
Sarilumab for active rheumatoid arthritis
This trial tests sarilumab, an injected antibody that blocks a key protein involved in inflammation, for people with moderate-to-severe rheumatoid arthritis (RA) who haven't had success with standard treatments. The goal is to see if adding sarilumab can help control joint pain and swelling.
Hollywood, FloridaAges 18 years+ - NCT06977724RecruitingPhase 1
Testing a new drug for lupus, sjogren's, and rheumatoid arthritis
This study tests an experimental medicine given by IV infusion to see if it is safe and helps reduce symptoms of lupus, sjogren's disease, or rheumatoid arthritis. It is an early-phase trial, so the main goals are checking side effects and how the drug behaves in the body, but it will also look at how well it works.
Avon Park, FloridaAges 18–75 - NCT07733518Recruiting
Exercise comparison for knee osteoarthritis
This trial compares two types of exercise—eccentric training and low-load blood flow restriction training—to see which is better for reducing pain and improving function in people with knee osteoarthritis.
Rawalpindi, Punjab ProvinceAges 40–70 - NCT06687551RecruitingPhase 4
Testing lower doses of JAK inhibitors for rheumatoid arthritis
This study tests whether people with rheumatoid arthritis whose disease is well controlled can safely take a lower dose of their JAK inhibitor medication. It aims to see if reducing the dose still keeps inflammation down and prevents flare-ups.
Toulouse, OccitanieAges 18–65 - NCT06733935RecruitingPhase 1/Phase 2
Study of NKX019 for immune diseases
This trial tests an investigational cell therapy called NKX019 for people with certain autoimmune diseases like scleroderma, myositis, vasculitis, or rheumatoid arthritis. It aims to see if NKX019 can help control the disease when standard treatments have not worked well enough.
Orange, CaliforniaAges 18–75 - NCT05062252Recruiting
Study of a new mirrored shoulder replacement system
This trial looks at a “mirror” shoulder replacement system for adults with painful shoulder arthritis who need their shoulder replaced. It aims to see how well the implant works and how safely it can be used for people who can follow study instructions.
BernAges 18 years+ - NCT03650010Recruiting
Study of ankle replacement outcomes over many years
This study looks at how well total ankle replacement surgery works and what the scans show over time. It mainly includes adults who had the surgery in a specific date range, to better understand results after ankle replacement.
Milan, MilanoAges 18 years+ - NCT05955976Recruiting
Fat tissue study in knee osteoarthritis patients
This study looks at fat tissue around the knee and inside the thigh muscle in people having knee replacement surgery for osteoarthritis. It may help researchers understand how fat tissue affects the knee joint.
NiceAges 40–85 - NCT06058169Recruiting
Home vibration therapy for arthritis knee pain
This study tests if doing whole-body vibration exercises at home can help reduce knee pain from arthritis. You stand on a gently vibrating platform for short periods over several weeks.
Augusta, GeorgiaAges 40–75 - NCT06038240Recruiting
Pain self-management program for knee replacement
This study is testing a program to help people manage pain on their own before and after total knee replacement surgery. It aims to improve recovery and reduce reliance on pain medications.
Charlottesville, VirginiaAges 18–85 - NCT05642260Recruiting
Fall-prevention program after knee replacement for older women
This trial tests whether a structured fall-prevention program can reduce the number of falls in older women after total knee replacement surgery. It may help you stay safer as you recover and move around.
Kuwait CityAges 60 years+ - NCT04728282Recruiting
RTSA surgery with or without repairing the subscapularis
This study compares two surgical approaches for RTSA (reverse shoulder replacement): doing a tendon repair on the front of the shoulder or not. It may help show which approach leads to better recovery and shoulder function for people who need their first RTSA.
Winnipeg, ManitobaAges 18 years+ - NCT04716803Recruiting
BMAC injection for severe knee osteoarthritis before knee surgery
This trial studies injecting “bone marrow aspirate concentrate” (BMAC) into the knee to help relieve pain from severe knee osteoarthritis. It’s for people who have strong signs of advanced arthritis on X-ray and still have ongoing pain despite usual treatments, before a planned knee procedure.
La Jolla, CaliforniaAges 45–75 - NCT04949087Recruiting
Shoulder arthritis injection study for ongoing pain relief
This trial looks at how well medicine given directly into the shoulder joint reduces pain from primary shoulder osteoarthritis. If you have ongoing shoulder pain confirmed by X-ray, you may be eligible to receive an in-joint injection and be followed for response.
Chicago, IllinoisAges 18 years+ - NCT04095637Recruiting
Compare two types of partial knee replacement surgeries
This study compares two implant types used for a partial knee replacement (only the inside/medial part) for people with “wear-and-tear” arthritis in that compartment. It looks to see which option leads to better outcomes after surgery and follow-up.
LondonAges 40–80 - NCT04458584Recruiting
Thumb surgery trial comparing treatments for basal joint arthritis
This study looks at how well different thumb (basal joint) surgery approaches restore strength and function. You would be having planned (non-replacement) thumb surgery, and your chosen surgeon would care for you while researchers compare outcomes.
Lebanon, New HampshireAges 21 years+ - NCT06974474RecruitingPhase 4
Guselkumab for pain in psoriatic arthritis
This study tests if guselkumab can reduce pain and inflammation in people with psoriatic arthritis. You may join if standard treatments have not worked well enough or caused side effects.
Rome, ItalyAges 18–80 - NCT05599776Recruiting
Smart ring-guided rehab after knee replacement surgery
This study tests whether using a smart ring along with physical therapy after knee replacement helps people recover better. It mainly looks at people’s rehab progress in the weeks after surgery.
Tampere, PirkanmaaAges 18–70 - NCT03017118Recruiting
Turmeric study for early thumb basal joint arthritis
This trial studies whether turmeric can reduce pain from “basal joint” arthritis in the thumb, especially early stages seen on X-ray. You may be a good fit if you’re having thumb base pain and meet specific exam and X-ray requirements.
Boston, MassachusettsAges 40 years+ - NCT07569549Recruiting
Thumb Base Surgery: Joint Replacement vs. Removal Comparison
This study compares two surgical approaches for thumb base arthritis: replacing the damaged joint with an implant or removing the problematic bone. Researchers want to see which approach works better for pain relief and hand function.
ÖrebroAges 40–80 - NCT06189495RecruitingPhase 2
Study of Genakumab for lung scarring from connective tissue disease
This study tests a new injected medication (Genakumab) for people with connective tissue disease-related lung scarring. It aims to see if it helps stabilize or improve lung function safely.
Beijing, Beijing MunicipalityAges 18–75 - NCT03404778Enrolling by invitation
Collecting data on reverse shoulder implants for weak rotator cuff
This study collects real-world information about a reverse shoulder implant used when the rotator cuff is badly damaged. It may help improve how these implants are chosen and how well they work for pain relief and improving arm function.
Towson, MarylandAges 18 years+ - NCT03286868Recruiting
Tested knee replacement alignment during knee surgery
This study looks at how a specific computer/measurement approach (“Verasense”) helps position the knee during total knee replacement for people with knee arthritis. It may help improve how the new knee fits and aligns as you recover.
Halifax, Nova ScotiaAges 21–80 - NCT07551245Recruiting
High-intensity laser vs traditional treatment for knee osteoarthritis
This study tests whether high-intensity laser therapy works better than traditional physical therapy methods for knee osteoarthritis pain and function. You'll be randomly assigned to receive either laser treatments or standard rehabilitation exercises.
Erbil, Erbil GovernorateAges 30–60
Hear when a new Arthritis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for arthritis?
- Yes. Clin2 currently lists 558 recruiting arthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a arthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a arthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.