Clinical trials
Barrett Esophagus clinical trials
Below are recruiting barrett esophagus clinical trials, each written for real people, not researchers. We’re tracking 45 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06720636Recruiting
New way to monitor long Barrett's esophagus using a sponge
This trial tests if a capsule-sponge device can replace endoscopy for monitoring people with ultralong-segment Barrett's esophagus. It aims to make surveillance easier and less invasive.
Rotterdam, South HollandAges 18 years+ - NCT06693622Recruiting
Patient preferences for Barrett's esophagus screening tests
This study asks people at risk for Barrett's esophagus (a condition that can lead to esophageal cancer) to share which screening test they prefer. Your answers help researchers understand what matters most to patients when choosing a screening method.
Aurora, ColoradoAges 18–89 - NCT06746623Recruiting
Non-endoscopic screening for Barrett's in veterans without reflux
This trial tests a new, non-endoscopic screening method for Barrett's esophagus (a condition that can lead to cancer) in veterans who do not have chronic acid reflux. It aims to find early signs of the condition using a simple swallowable device, potentially avoiding the need for a traditional endoscopy.
Cleveland, OhioAges 40–85 - NCT06523374Recruiting
Studying quality of life and cancer risk in Barrett's esophagus
This study looks at how Barrett's esophagus affects your quality of life and fear of cancer. It uses new tests to better predict who might develop esophageal cancer, so you can get the right care sooner.
Edegem, AntwerpenAges 18 years+ - NCT05745857RecruitingPhase 2
Scan for early esophagus cancer using infused antibody dyes
This Phase 2 study uses special drug dyes (bevacizumab and cetuximab, each tagged for imaging) during an esophagus scope to help doctors find very early abnormal cells, like low- or high-grade pre-cancer and superficial cancer. If you qualify, the goal is earlier detection and better targeting during diagnosis and treatment.
Groningen, Provincie GroningenAges 18 years+ - NCT05706025Enrolling by invitation
Testing a capsule to screen for Barrett’s and esophageal cancer
This study checks whether a swallowable capsule can help find signs of Barrett’s esophagus or esophageal cancer (or related risk) before or around an endoscopy. The goal is to see if this less invasive sampling method could improve screening.
Aurora, ColoradoAges 45 years+ - NCT06532734Recruiting
Barrett's Esophagus in people with purging eating disorders
This study checks if long-term purging (vomiting) in people with eating disorders can damage the tube that connects your mouth to your stomach (called the esophagus). The goal is to see how common Barrett's esophagus (a precancerous change) is in this group.
Denver, ColoradoAges 18–65 - NCT05216133Enrolling by invitation
Study WTC lung and reflux markers using noninvasive tests
This study looks at blood “biomarkers” and breathing/acid-reflux measurements in FDNY workers exposed to the 9/11 site to understand airway disease, Barrett’s esophagus, and reflux. It may help identify which people have hidden (underdiagnosed) reflux or lung involvement after 9/11.
New York, New YorkAges 37–90 - NCT04214119Recruiting
Capsule test during endoscopy to find early esophageal cancer
This trial studies an “EsophaCap” capsule that can be swallowed during an endoscopy to help detect early esophageal cancer. It may help find cancer earlier and guide next steps, if your results are concerning.
Baltimore, MarylandAges 18 years+ - NCT04312633Recruiting
Testing a new throat biopsy mapping method for Barrett’s disease
This study follows people for 5 years to see how well a new biopsy-mapping test (WATS3D) works during routine upper endoscopy. It may help doctors find Barrett’s esophagus changes earlier and better guide follow-up after treatment.
Bethpage, New YorkAges 18 years+ - NCT05133102Recruiting
Collecting saliva to study Barrett’s esophagus over time
This study collects saliva (and, for some people, looks at stomach/esophagus samples) to understand how the mouth and gut “microbiome” changes over time in people with Barrett’s esophagus. It may help researchers find patterns that relate to Barrett’s esophagus and future risk.
Ann Arbor, MichiganAges 18 years+ - NCT05463796Recruiting
Prevention and early detection for people at high cancer risk
This study looks at surveillance (watching closely), prevention, and early “interception” steps to lower the chance that cancer will develop or be found later. It is for people with genetic risk, past cancer treatment exposures, strong family history, or certain early pre-cancer or high-risk conditions.
Boston, MassachusettsAges Any age - NCT05468008Recruiting
Study of endoscopic submucosal removal (ESD)
This trial is checking outcomes for adults who are scheduled to have a procedure called endoscopic submucosal dissection (ESD), done through an endoscope. If you’re already planned for ESD and have no reasons you can’t have endoscopy, you may be able to join.
Orlando, FloridaAges 18 years+ - NCT06346054Recruiting
Breath and blood test for gastro-esophageal cancer and Barrett's esophagus
This study is testing whether a simple breath and blood test can help doctors better understand gastro-esophageal cancer and Barrett's esophagus. It aims to see if these non-invasive samples can provide useful information for diagnosis and monitoring.
LeuvenAges 18–100 - NCT03222635Recruiting
Follow-up for certain early esophageal cancer found by endoscopy
This study follows people whose early esophageal adenocarcinoma was found during an endoscopy (ER) sample. The goal is to better understand what follow-up tests are needed based on higher-risk features and to watch for spread or incomplete removal.
SydneyAges 18 years+ - NCT03853772Enrolling by invitation
Heartburn registry for long-term symptom and care follow-up
This registry enrolls people with GERD (chronic heartburn/reflux) to track symptoms and treatments over time for up to 5 years. It may help researchers understand what works best in everyday care, and you’ll be asked to complete check-in surveys.
Orange, CaliforniaAges 18 years+ - NCT02947971Recruiting
Test a pill-camera for viewing the esophagus in reflux patients
This study checks whether a small pill-camera (a capsule) can take clear pictures of the esophagus in people with reflux-related conditions. It may help doctors better see inflammation or narrowing so they can guide treatment.
Boston, MassachusettsAges 14–85 - NCT02198976Recruiting
Study for adults with Barrett’s esophagus
This study looks at people age 18+ who have Barrett’s esophagus and checks for early changes that may lead to cancer. You might qualify if you can consent and are not pregnant.
Westmead, New South WalesAges 18–99 - NCT05688176Recruiting
Testing blood RNA markers for esophagus cancer and Barrett’s
This study looks for helpful “RNA markers” found in blood to improve diagnosis in people with Barrett’s esophagus or esophageal cancer. It may help doctors spot disease more reliably, but it requires specific health and treatment conditions and a planned biopsy blood sample process.
Ghent, Oost-VlaanderenAges 18 years+ - NCT05818072Recruiting
Biopsy approach study for Barrett-like esophagus changes
This study looks at how common certain esophagus lining changes are, what increases risk, and which biopsy sampling method works best. It may help improve how doctors take tissue samples when Barrett’s esophagus is suspected.
Kaohsiung CityAges 20 years+ - NCT07346521Recruiting
Stomach cancer screening during routine colonoscopy
This study looks for early signs of stomach cancer and Barrett's esophagus (a precancerous condition) in people who are already getting a routine colonoscopy. By adding a quick upper endoscopy during the same visit, doctors can check for H. pylori infection and abnormal tissue changes without extra hassle.
ViennaAges 30 years+
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Common questions
- Are there clinical trials for barrett esophagus?
- Yes. Clin2 currently lists 45 recruiting barrett esophagus studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a barrett esophagus trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a barrett esophagus trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.