Clinical trials
Biologics clinical trials
Below are recruiting biologics clinical trials, each written for real people, not researchers. We’re tracking 636 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04359394Recruiting
Rare severe pustular psoriasis family DNA study network
This study builds a large international registry of people with rare, severe pustular psoriasis to help doctors understand the genetics of the condition. You may be asked for information and, if you have eligible family members, DNA testing to learn how the disease runs in families.
MünchenAges 6 months+ - NCT04396899RecruitingPhase 1/Phase 2
Stem cell heart patch for advanced heart failure
This early-phase study tests a lab-made heart tissue (“engineered myocardium”) placed surgically to help the heart work better in people with advanced heart failure. It mainly checks safety first, and also looks for signs the patch can improve heart function in selected patients.
Göttingen, Lower SaxonyAges 18–80 - NCT04413331Recruiting
Study follows adults with vasculitis over time
This observational study follows adults with vasculitis (inflammation of blood vessels) during an active flare or relapse. It aims to better understand how the disease changes over time and may help researchers plan future treatments.
ParisAges 18 years+ - NCT04442100Recruiting
Testing a new easy-change heart valve replacement system
This study tests a biological (tissue) heart valve replacement system designed to be easier to change later. It may help people who need valve surgery because their valve is narrowed or damaged.
Tomsk, Tomsk OblastAges 60 years+ - NCT04458792Recruiting
Builds a cancer blood-and-biomarker database after sarcoma treatment
This study collects information and blood samples from adults with sarcoma who had surgery and possibly radiation. The goal is to build a large dataset that helps researchers understand sarcoma better and improve future care.
Montpellier, HeraultAges 18 years+ - NCT04621357Recruiting
Testing how brain swelling affects recovery after brain bleeding
This study looks at brain swelling (“cerebral edema”) after a spontaneous brain bleed and how it relates to outcomes. It mainly involves people who can have early care and MRI scans, to better understand what affects recovery.
LilleAges 18 years+ - NCT04690972Recruiting
Collection of blood and tissue samples for liver disease research
This study builds a research library of biological samples (like tissue and blood) from people with chronic liver disease. It aims to create better lab and preclinical models of tumors and long-term liver problems, which may help future treatments.
StrasbourgAges 18 years+ - NCT04698421Recruiting
Blood and tissue sample collection for rare autoimmune nerve diseases
This study collects biological samples (like blood or other specimens) from people with rare neurological conditions that may involve the immune system. Your samples may help researchers better understand these diseases.
ToulouseAges 6–99 - NCT04704089Recruiting
Dental enamel defect study using tooth photos and measurements
This study compares different types of enamel problems by taking detailed pictures of your front teeth. It may help researchers better tell these enamel conditions apart and improve future diagnosis and care.
ParisAges 8–55 - NCT04706481Recruiting
Use of stored, de-identified samples for research
This trial is for people who already agreed to let researchers use their stored biological samples and medical information that has been removed of personal identifiers. It may help future studies by allowing researchers to analyze existing samples without using new samples from you.
Hong KongAges Any age - NCT04758325Recruiting
Sarcoma biology and outcomes registry
This trial is a health registry that collects information about people with soft-tissue or bone sarcoma. It helps researchers understand how the disease behaves and what outcomes different treatments lead to.
Heidelberg, Baden-WurttembergAges 12 years+ - NCT04784364Recruiting
Study of immune treatments at Mount Sinai
This study follows people who are receiving immune-related medications (called biologics or immune modulators) at Mount Sinai. It aims to better understand how these treatments affect the immune system and health over time, which may help improve future care.
New York, New YorkAges 12 years+ - NCT04804878Recruiting
Cancer care program for adults to help manage cancer
This study is a general cancer care program for adults (and in some cases people at risk for cancer). It aims to improve how cancer care is organized and delivered, and you may benefit from extra care support through the program.
Atlanta, GeorgiaAges 18 years+ - NCT04817072Recruiting
Studying mood changes in inflammatory arthritis patients on biologics
This study looks at how mood disorders (like depression or anxiety) affect people with chronic inflammatory joint diseases when they use biologic medicines. It may help doctors understand which patients are at higher mood-risk and how to monitor them.
BesançonAges 18–80 - NCT04833751Recruiting
Study of heart and brain monitoring around heart surgery anesthesia
This study collects heart and brain signal information before and during anesthesia for people having cardiovascular surgery or procedures. The goal is to better understand risk and outcomes, and to improve how anesthesia is assessed.
SeoulAges 19 years+ - NCT04844151Recruiting
Registry study for acute myocarditis with heart imaging
This study collects information from people with newly diagnosed acute myocarditis using heart scans and, in some cases, a biopsy. It aims to understand what predicts recovery and which test results matter most for outcomes.
ParisAges 15 years+ - NCT04854213Recruiting
Study checks radiation effects in colon cancer lung-limited spread
This trial studies how targeted radiation (SBRT) affects cancer biology and immune cells in people with colon cancer that has spread only to a small number of lung nodules. Your tumor tissue will be analyzed to see what changes after treatment.
Naples, NAPOLIAges 18–80 - NCT04859088Recruiting
Biologics plus partial tube-feeding for Crohn’s disease
This study tests whether starting adalimumab along with partial enteral (tube or drink) nutrition helps control active Crohn’s disease. It may help reduce symptoms and inflammation compared with standard care alone.
Glasgow, ScotlandAges 16 years+ - NCT04873492Recruiting
Study how genes and blood signals relate to MS outcomes
This study looks at genetic information and blood test signals to understand why some people with early MS develop a worse outcome. It may help doctors predict who is at higher risk and better understand disease mechanisms.
Nantes, Loire-AtlantiqueAges 18 years+ - NCT04883502Recruiting
Testing a technique to rebuild bone lost after injury
This study looks at a surgical method that creates an “induced membrane” to help rebuild bone after traumatic injury. It may help people whose limb bones were damaged and are missing part of the bone.
ClamartAges 18 years+ - NCT04903236Recruiting
MRI and body test study during planned radiotherapy
This study uses MRI scans and blood and/or urine tests to measure changes in the body and imaging results during radiotherapy. It may help researchers understand how treatment affects the body and improve future planning.
ManchesterAges 18 years+ - NCT04917705Recruiting
Blood and tissue tests to find markers in muscle and skin disease
This study looks for blood and tissue “biomarkers” (measurable clues in samples) to help diagnose and predict outcomes in inflammatory muscle diseases and systemic sclerosis (a skin/organ condition). If you’re being evaluated for myopathy or early scleroderma, it may help doctors sort out the cause and follow your health more closely.
Strasbourg, Bas-RhinAges 18 years+ - NCT07511959Enrolling by invitation
Blood-derived treatment for chronic jaw pain
This trial tests whether a treatment made from your own blood (platelet-rich plasma exosomes) can help relieve long-term jaw joint pain and improve function. If you qualify, you would receive injections directly into your jaw area.
WroclawAges 18 years+ - NCT04944030Recruiting
Study collects health data for metastatic lung cancer patients
This study collects medical information and test results from people with lung cancer that has spread (or cannot be cured with local treatment). It does not test a new drug; it helps researchers better understand patients’ health and care needs over time.
AngersAges 18 years+
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Common questions
- Are there clinical trials for biologics?
- Yes. Clin2 currently lists 636 recruiting biologics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a biologics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a biologics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.