Clinical trials
Biologics clinical trials
Below are recruiting biologics clinical trials, each written for real people, not researchers. We’re tracking 636 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04945369Recruiting
Follow-up for some very preterm children during puberty
This study follows children who were born very prematurely to better understand body changes during puberty. It involves follow-up visits and special body-composition measurements to see how growth and health progress over time.
NantesAges 8–14 - NCT04946721Recruiting
Study of eye-surface disease tests and targeted treatment
This study looks at how an “ocular surface” condition can be identified using tests (biomarkers) and how a targeted treatment may help. You may qualify if you’re an adult receiving eye care at specific University of Maryland locations.
Baltimore, MarylandAges 18 years+ - NCT04946448Recruiting
Test a Crohn’s diet and biologic medicine combination
This study tests whether combining a specific diet with biologic medicines can reduce active inflammation and symptoms of Crohn’s disease. It may help people who still have active disease in the bowel despite prior care.
LeuvenAges 18–80 - NCT04970459Recruiting
Collecting samples for Marfan and related conditions
This study collects biological samples and related health information for people with Marfan syndrome or similar inherited conditions. It helps researchers better understand these conditions and may lead to improved care for patients in the future.
ToulouseAges 3–99 - NCT04995224Recruiting
Study what causes long-term pain in new Crohn’s or colitis
This study looks at why some people develop long-term pain after being newly diagnosed with ulcerative colitis or Crohn’s disease. It may help researchers understand the pain process and improve future treatments.
LondonAges 18 years+ - NCT05007340Recruiting
ILD and autoimmune conditions registry and sample storage
This study collects health information and may store blood or other samples to learn more about interstitial lung disease (ILD) and autoimmune-related conditions. Joining could help researchers understand different causes of ILD and improve future care.
Montreal, QuebecAges 18 years+ - NCT05012111Recruiting
Study of bone marrow failure causes over time
This study looks at the natural history (how a condition progresses) in people with acquired or inherited bone marrow failure syndromes, including related lung and liver findings in some cases. It helps researchers understand underlying causes—sometimes linked to gene or telomere changes—and how symptoms evolve, which may guide future care.
Bethesda, MarylandAges 2–99 - NCT05062421Recruiting
Study how well arthritis treatments keep working over time
This study looks at people with adult rheumatoid arthritis to see how long biological medicines and “JAK inhibitors” keep helping. It uses routine clinic follow-up records to understand how well treatment persists over time and how outcomes change.
SevilleAges 18 years+ - NCT05089227RecruitingPhase 2
Long-term apixaban to prevent clots in autoimmune hemolytic anemia
This Phase 2 trial tests whether taking long-term apixaban (a blood thinner) can prevent venous blood clots in people with autoimmune hemolytic anemia (AIHA). It may help reduce the risk of dangerous clotting events if you meet safety and risk criteria.
DijonAges 18 years+ - NCT05122806Recruiting
Study of cancer biology in ALK-positive advanced lung cancer
This study looks at biological changes in advanced lung cancer that has an ALK rearrangement, using regular blood samples (and sometimes tumor tissue if available). It may help researchers better understand how this cancer behaves and how it responds to first-line ALK-targeted treatment.
Saint-Denis, La RéunionAges 18 years+ - NCT05140889Recruiting
AI helps predict asthma severity in children
This trial studies an AI (computer) model that uses CT scan images plus health and blood/clinical information to predict how severe asthma is in children. It may help doctors better understand your child’s asthma severity and tailor care.
PaviaAges 6–17 - NCT05186623Recruiting
Personalized prediction for ulcerative colitis treatment response
This study builds a prediction model to estimate how people with ulcerative colitis may respond to certain medicines. It may help doctors choose the most effective treatment sooner.
SeoulAges 18–79 - NCT05198661Recruiting
Blood or spinal fluid study in autoimmune brain disorders
This study collects information from people with autoimmune encephalitis or related nerve/brain disorders, using blood and sometimes spinal fluid. It helps researchers better understand these conditions, which may guide future diagnosis and treatments.
Pointe à Pitre, GuadeloupeAges Any age - NCT05202210Recruiting
Biobank study for people with Noonan syndrome
This study collects biological samples to better understand what causes Noonan syndrome. If you qualify, your participation could help researchers learn how the condition works and guide future care.
ToulouseAges 18–99 - NCT05217043Recruiting
Study brain recordings to track how meanings are learned
This study uses long-term recordings from inside the brain to see how your brain (and computers) builds and changes meaning over time as learning happens. Your participation may help researchers improve how we monitor language and meaning in both humans and artificial systems.
Paris, FranceAges 18 years+ - NCT05219058Recruiting
Rebuilding after major pelvic cancer surgery
This study looks at reconstruction (how tissue is rebuilt) after very large pelvic cancer surgeries. It may help teams improve the options and support for people having these operations and recovery experiences.
Southampton, HampshireAges 18 years+ - NCT05237440Recruiting
Childhood trauma and stress hormones in women with obesity
This study looks at how childhood trauma might affect stress hormones (cortisol) and inflammation in women with obesity. It aims to find connections that could lead to better treatments.
LimogesAges 18 years+ - NCT05251415Recruiting
Study of rare autoimmune diseases with blood and medical samples
This trial collects clinical and lab information (like blood and medical history) from people with rare autoimmune diseases, especially when symptoms are unusual. It aims to better understand what causes these illnesses and how newer treatments may help.
ToulouseAges 6–99 - NCT05263804Recruiting
Study uses MRI and blood clues after ischemic stroke
This study looks for biological and imaging markers that may predict heart/vascular outcomes after an ischemic stroke. You may join if you are eligible for standard stroke treatment and can complete planned follow-up and MRI scans.
BronAges 18 years+ - NCT05265429Recruiting
Study of young people’s lung cancer biology
This study looks at biological samples from people diagnosed with lung cancer at age 45 or younger. It may help researchers understand how young lung cancers differ, which could guide future treatments.
Boston, MassachusettsAges 15 years+ - NCT05299762Recruiting
INFUSE bone graft for lower back fusion: patient follow-up study
This study tracks patients who receive INFUSE bone graft during a specific type of lower back fusion surgery. It helps confirm how the device performs in real-world care and monitors safety and outcomes after surgery.
SeoulAges 18 years+ - NCT05318196Recruiting
Predict kidney disease risk and progression from patient data
This trial looks at ways to predict how kidney disease may develop, change, or cause complications using information from patients. It may help doctors identify people at higher risk and tailor care earlier.
ToulouseAges 18–99 - NCT05327790RecruitingPhase 2
Fecal transplant to boost new biologic treatment for ulcerative colitis
This trial tests whether fecal microbiota transfer (a stool-based therapy) can improve outcomes when added to starting a new biologic medicine for ulcerative colitis. It compares fecal transplant versus placebo (a sham treatment) to see if symptoms and inflammation improve faster or more strongly.
Edmonton, AlbertaAges 18–75 - NCT05354141RecruitingPhase 3
Tested treatment with tiny lung particles for moderate to severe ARDS
This Phase 3 trial studies an “extracellular vesicle” treatment in people with moderate to severe ARDS, a serious lung breathing problem. The goal is to see whether the treatment can improve outcomes compared with standard care.
Phoenix, ArizonaAges 18–75
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Common questions
- Are there clinical trials for biologics?
- Yes. Clin2 currently lists 636 recruiting biologics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a biologics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a biologics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.