Clinical trials
Biologics clinical trials
Below are recruiting biologics clinical trials, each written for real people, not researchers. We’re tracking 638 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05701111Recruiting
School-based treatment for teens with trauma symptoms
This study tests a school-based approach to help teens who have experienced trauma and now have post-trauma symptoms. It also collects emotional and physical (biologic) information to understand how treatment may help.
Palo Alto, CaliforniaAges 11–17 - NCT05756985Recruiting
Providing fresh brain tissue to better understand glioblastoma
This study aims to improve understanding of glioblastoma (and gliosarcoma) by preserving live, usable brain-tissue samples during brain surgery. If you’re having repeat tumor surgery or your scans suggest these cancers, the study may ask to collect tissue for research.
Miami, FloridaAges 18 years+ - NCT05767203Recruiting
Study genetic and blood markers in people with inherited intellectual disability
This study looks at genetic-related and blood/biologic markers in people with an inherited (genetic) intellectual disability. The goal is to better understand these differences and how they might relate to the condition.
ParisAges Any age - NCT05767216Recruiting
Study of genetic and epigenetic differences in twin pairs with Down syndrome
This study looks at how genetics and gene-regulation (how genes turn on and off) differ between close family members who have different Down syndrome status. Researchers hope the findings will help explain why Down syndrome outcomes can vary even in very closely related people.
ParisAges 4–11 - NCT05770765Recruiting
Biobank for infections and tropical diseases
This study sets up a library (biobank) of biological samples and related health data from people with infectious or tropical diseases. Your samples and information help researchers study these illnesses and develop better tests or treatments.
Negrar, VeronaAges Any age - NCT05775458Recruiting
Study of treatments for aggressive brain tumor cell damage
This study looks at glioblastoma (GBM), a very aggressive brain tumor, and how “brain cell overload” (glutamate excitotoxicity) may affect tumor growth. It focuses on adults who are planned for complete tumor removal, followed by standard radiation and chemotherapy.
Milan, MilanAges 18 years+ - NCT05786235Recruiting
Pregnant people with or without antiphospholipid antibodies
This study is looking at pregnancy outcomes in people who are pregnant and either have antiphospholipid antibody syndrome (APS) or do not have APS but do have prior full-term pregnancies. It may help doctors understand risks and how to manage pregnancies in these groups.
MilanAges 18–45 - NCT05787795Recruiting
Studying early risk signs for multiple sclerosis
This study looks at people who are at higher risk for multiple sclerosis (MS), to better understand early changes before MS is diagnosed. It may help doctors identify who is more likely to develop MS and how to monitor them sooner.
North Haven, ConnecticutAges 18 years+ - NCT05793034Recruiting
Study factors that predict survival after aggressive meningioma surgery
This study looks at people who had surgery for more aggressive meningiomas (grade 2 or 3) and tries to learn what factors relate to survival. The results may help doctors better predict outcomes for future patients.
RomeAges 18 years+ - NCT05816850Recruiting
Advanced follicular lymphoma study using your lab samples
This study looks at advanced follicular lymphoma by analyzing samples of blood and tissue (and sometimes bone marrow) you may have already provided. It may help doctors understand your lymphoma better and improve future treatments.
AlessandriaAges 18 years+ - NCT05839392Recruiting
Targeting MECOM/EVI1 in AML
This trial studies new ways to target a specific genetic change in acute myeloid leukemia (AML), called MECOM or atypical 3q26 rearrangements. If your leukemia test shows one of these changes, the study may offer a treatment approach aimed at that target.
PiacenzaAges 18 years+ - NCT05855083RecruitingPhase 2
Narsoplimab for high-risk TMA after bone marrow transplant
This trial studies the medicine narsoplimab in children who develop a serious complication called HSCT-TMA after a bone marrow transplant. It aims to improve safety and effectiveness for high-risk cases where the condition is ongoing or causing organ problems.
San Diego, CaliforniaAges 4 weeks–17 years - NCT05857774Recruiting
Study breathing muscle changes in ICU patients on ventilation
This study looks at how the muscles used for breathing work and change in ICU patients who are placed on breathing machines, then follows outcomes after they leave the hospital. It may help doctors better predict recovery and long-term health after ventilation.
Toronto, OntarioAges 18 years+ - NCT05858411Recruiting
Biologic gum treatments added to non-surgical cleaning
This trial studies whether adding a biologic medicine to standard non-surgical gum (periodontal) treatment can improve deep gum pockets in certain bone defects. It may help people whose gum disease has specific “intrabony” defects, but you must meet several health and medication rules.
TiranaAges 18 years+ - NCT05892718RecruitingPhase 1
Testing an immune drug for hard-to-treat cancers
This early-phase study tests HCB101, an immune-targeting drug, to see if it is safe and can shrink certain solid tumors or non-Hodgkin lymphoma. It may help people whose cancer has returned or stopped responding to standard treatments.
Port Saint Lucie, FloridaAges 18 years+ - NCT05896865Recruiting
Personalized breast cancer radiation based on tumor biology
This trial studies whether adjusting radiation dose using how the tumor behaves can improve outcomes for people with locally advanced breast cancer that has spread to certain nearby lymph nodes. It may help deliver the right radiation intensity while avoiding unnecessary exposure.
SeoulAges 19 years+ - NCT05924074Recruiting
Study of ferroptosis therapy in blood disorders with SF3B1 mutation
This study looks at ferroptosis (a type of cell stress that can affect blood-forming cells) in people with certain blood disorders linked to an SF3B1 gene change. It may help researchers understand whether targeting this pathway could improve outcomes.
PessacAges 18 years+ - NCT05936333Recruiting
Study why repeated pregnancy problems happen in some cases
This study looks at how the immune system may contribute to ongoing placenta inflammation in certain pregnancy histories. It may help researchers better understand causes behind pregnancy loss and related placental complications, using past placenta/tissue samples.
ClamartAges 18 years+ - NCT05941234Recruiting
Studying stem cells and blood patterns in glioblastoma
This study analyzes tissue and health-related biological data from people with glioblastoma to learn what’s happening in the tumor. The results may help improve future ways to understand and treat glioblastoma using advanced computer analysis.
RomeAges 18 years+ - NCT05943210Recruiting
Molecular testing of rectal cancer after short-course radiation
This study looks at molecular (tumor biology) features of rectal cancer in people receiving standard short-course radiation. Your tissue and/or samples may be used to better understand the cancer and how it responds to treatment.
Chicago, IllinoisAges 18–90 - NCT05968053Recruiting
Testing microplastics detection in neurosurgery patients
This study checks whether microplastics and nanoplastics can be detected in people undergoing neurosurgery. If it works, it could help doctors better understand possible material exposures around brain and nerve procedures.
Beijing, Beijing MunicipalityAges 18–80 - NCT05983991Recruiting
Study of GATA2 gene changes over time
This study looks at how GATA2 gene changes affect your blood cells over time. It is for people of any age who have a GATA2 mutation they were born with, and it does not test a new drug—just collects information and samples during regular checkups.
AngersAges Any age - NCT06007534Recruiting
Doxycycline for STI Prevention After Sex
This study looks at how a single 200 mg dose of doxycycline works in the body to prevent bacterial sexually transmitted infections (like chlamydia, gonorrhea, and syphilis) after a risky sexual encounter. It is for men who have sex with men and are already on PrEP or living with HIV.
ParisAges 18–100 - NCT06016075Recruiting
Studying kidney masses with advanced MRI
This study uses advanced MRI scans to better understand the differences between non-cancerous and cancerous kidney growths. It may help doctors improve how they diagnose and treat kidney masses.
Cambridge, CambridgeshireAges 18 years+
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Common questions
- Are there clinical trials for biologics?
- Yes. Clin2 currently lists 638 recruiting biologics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a biologics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a biologics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.