Clinical trials
Biologics clinical trials
Below are recruiting biologics clinical trials, each written for real people, not researchers. We’re tracking 637 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05327790RecruitingPhase 2
Fecal transplant to boost new biologic treatment for ulcerative colitis
This trial tests whether fecal microbiota transfer (a stool-based therapy) can improve outcomes when added to starting a new biologic medicine for ulcerative colitis. It compares fecal transplant versus placebo (a sham treatment) to see if symptoms and inflammation improve faster or more strongly.
Edmonton, AlbertaAges 18–75 - NCT05354141RecruitingPhase 3
Tested treatment with tiny lung particles for moderate to severe ARDS
This Phase 3 trial studies an “extracellular vesicle” treatment in people with moderate to severe ARDS, a serious lung breathing problem. The goal is to see whether the treatment can improve outcomes compared with standard care.
Phoenix, ArizonaAges 18–75 - NCT05361694Recruiting
Study aims to distinguish stable vs worsening early myeloma
This study looks at two different “precursor” conditions that can happen before multiple myeloma: MGUS and smoldering myeloma (SMM). Researchers want to better tell which cases are more likely to progress, using blood/urine tests and sometimes bone marrow tissue.
Miami, FloridaAges 18 years+ - NCT05370079Recruiting
Control group for people with specific serious illnesses
This trial includes a “control” group of people with certain diseases to compare outcomes against another group. If you qualify, you may receive the standard approach used in usual care rather than the experimental treatment.
BronAges 18 years+ - NCT05403554RecruitingPhase 1
Testing a new mesothelin-targeting drug for certain solid cancers
This Phase 1 study tests NI-1801, a drug designed to attach to a target on cancer cells (mesothelin). It may be given alone or with pembrolizumab to help shrink tumors in advanced cancers that have enough mesothelin on their cells.
ParisAges 18 years+ - NCT05421325RecruitingPhase 2
Vaccine-like immune treatment to prevent lung infections in seniors
This Phase 2 study tests a site-specific immune “booster” in people age 65 and older to help improve natural immunity and reduce respiratory (lung/airway) infections. You may be eligible if you can consent, are in an eligible living situation, and are not currently using certain immune-suppressing medicines.
Burnaby, British ColumbiaAges 65 years+ - NCT05429138Recruiting
Tracking egg and sperm changes during melanoma treatment
This study measures how anti-cancer treatment affects a person’s egg reserve (for women) or semen quality (for men) over time. It may help doctors better understand fertility-related side effects of melanoma therapy and how they evolve during routine treatment.
BordeauxAges 18–45 - NCT05449691Recruiting
Compare natural tissue samples with synthetic mesh in breast reconstruction
This study looks at how “biological” materials compare with synthetic mesh during immediate, one-stage breast reconstruction after mastectomy. It may help doctors choose the best support material to improve reconstruction outcomes for women undergoing this surgery.
DerbyAges 18 years+ - NCT05533060Recruiting
Collecting brain injury data from people treated soon
This study collects medical and test information from people who have a confirmed brain injury (TBI) and arrive at the emergency room within 12 hours. Doctors hope the collected clinical and lab data will help better understand TBI and improve future care.
ShanghaiAges Any age - NCT05536388Recruiting
Study of a new drug for GBA-related Parkinson’s
This study is looking for ways to find new drugs that may help people with Parkinson’s caused by changes in the GBA gene. It may also include people with Gaucher disease and healthy volunteers, using blood and possibly skin samples.
New York, New YorkAges 18 years+ - NCT05540561Recruiting
Testing and monitoring for nitrous oxide use
This study looks at how nitrous oxide (also called laughing gas) is detected and how health effects may show up over time. It may help doctors better diagnose problems early and track changes after use.
BéthuneAges 14–65 - NCT05552287RecruitingPhase 4
Infliximab drug levels in children with Crohn’s disease
This study measures how infliximab (a medicine that calms immune inflammation) moves through the body in children with Crohn’s disease. It mainly helps doctors understand dosing and drug levels, especially when treatment is newly starting.
RotterdamAges 1–15 - NCT05571579Recruiting
Collecting blood and tissue samples from confirmed brain tumors
This study collects biological samples from adults with a confirmed brain tumor. Samples may help researchers better understand brain tumors and improve future treatments.
Bron, RhôneAges 18 years+ - NCT05591924Recruiting
Bioinformatics study in adults with very early severe ICU illness
This trial studies how early severe illness in the ICU can be understood and tracked using health data (bioinformatics/informatics). It may help improve care decisions for people who arrive to the ICU soon after an emergency department visit.
London, OntarioAges 18 years+ - NCT05625529Recruiting
Study blood test to detect pancreatic cancer early
This trial studies how well a new blood-based test may help find pancreatic cancer earlier. You may join if you’re an adult who fits a specific risk group and can safely provide a blood sample.
San Diego, CaliforniaAges 18 years+ - NCT05627713Recruiting
Studying monkeypox infection and vaccine in adults
This study looks at the medical and lab changes in people with suspected or likely monkeypox, and in adults who may be eligible for a monkeypox vaccine. Your participation helps researchers understand how infection and vaccination affect the body and how to improve care.
ParisAges 18 years+ - NCT05632978Recruiting
Study of epilepsy using real-world patient data
This is an observational study that looks at how epilepsy is diagnosed and how people do over time, using information from routine care. It may help doctors better understand epilepsy biology and outcomes using real-world data.
CardiffAges 16 years+ - NCT05633875Recruiting
MRI study to better understand worsening in multiple sclerosis
This study uses detailed imaging (mostly MRI) to look for patterns that may explain why multiple sclerosis can worsen. It may help researchers understand the biology behind neurodegeneration and improve future care.
ParisAges 18 years+ - NCT05639413Recruiting
Study of biology in people with BRAF V600E metastatic colon cancer
This study follows people with BRAF V600E–positive metastatic colorectal (colon) cancer to better understand how the cancer’s biology changes over time. It may help researchers learn which features to watch and how this cancer behaves after initial treatment.
AvignonAges 18 years+ - NCT05666739Recruiting
Store your sample for future research studies
This study collects and stores your biological samples so researchers can use them for future environmental health questions. You might join if you’re an adult, can travel for visits, and agree to have your samples stored for later use.
Research Triangle Park, North CarolinaAges 18–100 - NCT05683873Recruiting
Study of heart stress after stroke using a blood marker
This study looks at how heart function changes soon after a new stroke, and whether a blood marker called GDF-15 can help explain or predict that change. It may help doctors better monitor heart stress after stroke and tailor care sooner.
DijonAges 18 years+ - NCT05694325Recruiting
Studying biologic features in adults with newly diagnosed ITP
This study looks at blood and immune system patterns in adults with primary immune thrombocytopenia (ITP) who are starting their first treatment. The goal is to better understand what’s happening in ITP, which may improve how future patients are cared for.
BolognaAges 18 years+ - NCT05701111Recruiting
School-based treatment for teens with trauma symptoms
This study tests a school-based approach to help teens who have experienced trauma and now have post-trauma symptoms. It also collects emotional and physical (biologic) information to understand how treatment may help.
Palo Alto, CaliforniaAges 11–17 - NCT05756985Recruiting
Providing fresh brain tissue to better understand glioblastoma
This study aims to improve understanding of glioblastoma (and gliosarcoma) by preserving live, usable brain-tissue samples during brain surgery. If you’re having repeat tumor surgery or your scans suggest these cancers, the study may ask to collect tissue for research.
Miami, FloridaAges 18 years+
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Common questions
- Are there clinical trials for biologics?
- Yes. Clin2 currently lists 637 recruiting biologics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a biologics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a biologics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.