Clinical trials
Bone Diseases, Infectious clinical trials
Below are recruiting bone diseases, infectious clinical trials, each written for real people, not researchers. We’re tracking 32 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04536103Recruiting
Accelerated MRI scans after ACL knee injury surgery
This trial tests a faster MRI scan method to measure healing in the knee after an ACL (anterior cruciate ligament) tear and reconstruction. It may help researchers compare scan quality while participants go through standard rehab.
Cleveland, OhioAges 18–50 - NCT05610098Recruiting
Study of gene activity in spinal tuberculosis
This trial looks at patterns of gene activity (from blood/tissue samples) in adults with spinal tuberculosis. The goal is to better understand the disease and how to tell different conditions apart, which may help future care.
Cape Town, Western CapeAges 18 years+ - NCT02979951Recruiting
IV fosfomycin for serious bacterial infections
This trial studies whether IV (through a vein) fosfomycin can treat severe bacterial infections in adults. It may help people whose infection is covered by the standard fosfomycin use and who need hospital-level care.
Hall in TirolAges 18 years+ - NCT00001405Recruiting
Blood Cell Collection Study for Immune and Blood Disorders
This study collects blood cells and bone marrow from people with immune system or blood disorders, and from healthy volunteers. Researchers will study these cells and may convert them into special stem cells (iPS cells) to better understand diseases and develop treatments.
Bethesda, MarylandAges 18–70 - NCT00044122Recruiting
Study of mast cell growth in people with mastocytosis
This study looks at what causes mast cells to grow too much in people with mastocytosis. It may help researchers find better ways to diagnose or treat this condition. You can take part in person or by telehealth.
Bethesda, MarylandAges 1 day–80 years - NCT06418048Recruiting
Infectious disease registry and biobank trial
This study collects medical information and optional biological samples (like blood or saliva) from people with an active or suspected infection. The goal is to build a large database that can help researchers better understand infectious diseases and develop new ways to diagnose and treat them.
MilanAges 18 years+ - NCT00032513Recruiting
Genetic study of chronic active Epstein-Barr virus disease
This research study looks for genetic factors that may explain why some people develop severe, long-lasting Epstein-Barr virus (EBV) infection. Researchers will study blood and tissue samples from patients with this rare condition, their healthy relatives, and unrelated volunteers to understand the disease better.
Bethesda, MarylandAges 1–120 - NCT06253507Enrolling by invitationPhase 1/Phase 2
Gene therapy for p47 chronic granulomatous disease
This trial tests a new gene therapy for people with a specific type of chronic granulomatous disease (p47 CGD). The treatment uses your own blood stem cells, which are modified in a lab to help your body fight infections better. It is for people who do not have a matched stem cell donor and have had serious infections.
Bethesda, MarylandAges 3–65 - NCT07113743Enrolling by invitationPhase 1/Phase 2
Gene therapy for x-linked chronic granulomatous disease
This trial tests a new gene therapy for X-linked chronic granulomatous disease (CGD), a condition where the immune system cannot fight certain infections. The treatment uses your own blood stem cells, which are modified in the lab to help your body produce working immune cells.
Bethesda, MarylandAges 3–60 - NCT06325709RecruitingPhase 1/Phase 2
Gene editing trial for X-linked chronic granulomatous disease
This trial tests a new gene-editing treatment for men with a specific genetic mutation that causes X-linked chronic granulomatous disease (CGD). The goal is to fix the faulty gene in your own blood stem cells to help your immune system fight infections better.
Bethesda, MarylandAges 18–75 - NCT06832189RecruitingPhase 1
Testing everolimus and epoetin for liver transplant tolerance
This trial is testing whether a combination of two drugs, everolimus and epoetin, can help liver transplant recipients gradually reduce their anti-rejection medicines. If successful, it may lead to long-term transplant tolerance with fewer side effects.
San Francisco, CaliforniaAges 18 years+ - NCT07706686RecruitingPhase 1
Dengue challenge study in people with prior infection
This study tests how the body responds to a mild, lab-made dengue virus in people who have had dengue before. It looks at how the immune system reacts to a second infection, which may help improve future vaccines and treatments.
Bethesda, MarylandAges 18–50 - NCT07216794RecruitingPhase 2
Alendronate trial to reduce hidden HIV
This study tests if alendronate, a bone-strengthening medicine, can shrink the reservoir of HIV that stays in your body even when on treatment. You must have well-controlled HIV on antiretroviral therapy for at least one year but no more than ten years, and meet specific health requirements.
San Francisco, CaliforniaAges 18–65 - NCT06476132RecruitingPhase 2
Belumosudil for lung transplant patients at risk of chronic rejection
This trial tests whether the drug Belumosudil can help prevent chronic lung rejection in people who recently had a lung transplant and showed signs of early rejection. It may improve long-term lung health.
Los Angeles, CaliforniaAges 12 years+ - NCT06918990RecruitingPhase 1
CarBel for antibody-mediated rejection after kidney transplant
This study tests a new drug called CarBel to treat antibody-mediated rejection in kidney transplant patients. The goal is to see if it can help stop the rejection and protect your new kidney.
Birmingham, AlabamaAges 18–75 - NCT04020536Recruiting
Real-world study for several infectious diseases
This study follows people with confirmed brucellosis, epidemic hemorrhagic fever, or kala-azar (visceral leishmaniasis) to understand how these infections behave in real life. It may help improve care by collecting evidence on diagnosis and treatment outcomes.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05587894RecruitingPhase 2
Testing optimized COVID antiviral treatment in immunocompromised adults
This study tests the best combination and timing of antiviral medicines for people with COVID-19 who have weakened immune systems. It aims to improve outcomes in people with mild to moderate illness.
Bordeaux, BordeauxAges 16 years+ - NCT06024421RecruitingPhase 1
Testing high doses of favipiravir in healthy volunteers
This study tests the safety and how the body processes very high doses of the antiviral drug favipiravir in healthy people. It helps find the highest dose that is still safe before testing in patients.
ParisAges 18–75 - NCT06056102RecruitingPhase 1
CAR-T cell therapy to help highly sensitized kidney transplant patients
This trial tests whether a special immune cell treatment (CAR-T cells) can lower the antibodies that make it very hard for you to receive a kidney transplant. If it works, you might become eligible for a transplant sooner.
Boston, MassachusettsAges 18–65 - NCT06339177Recruiting
HLH study looking at immune system and genes
This study is for people with hemophagocytic lymphohistiocytosis (HLH), a condition where the immune system becomes overactive. Researchers want to collect medical data and blood samples to better understand HLH and find better ways to diagnose and treat it.
Bethesda, MarylandAges 18–120 - NCT06787560RecruitingEarly Phase 1
CAR-T cells and stem cell transplant for blood diseases
This trial tests a new approach for people with non-cancerous blood and immune system diseases. It uses your own engineered immune cells (CAR-T cells) to prepare your body for a stem cell transplant from a relative.
Hangzhou, ZhejiangAges Any age - NCT07308457Recruiting
Comparing infection monitoring vs. antibiotic prevention in stem cell transplant
This trial compares two ways to prevent infections after a stem cell transplant: using a standard antibiotic (ceftriaxone) or closely watching for germs in the blood and treating only if needed. It aims to find which method is safer and more effective for people receiving a stem cell transplant.
Szczecin, West Pomeranian VoivodeshipAges 18 years+ - NCT00001352Recruiting
Understanding Why Some People Get Fungal Infections
This study looks at genetic reasons why some people are susceptible to a serious fungal infection called cryptococcosis. Researchers will collect blood samples and perform genetic testing to understand the immune system differences that make certain individuals more vulnerable to this infection.
Bethesda, MarylandAges 18–99 - NCT00090662Recruiting
Healthy Volunteer Sample Collection for Medical Research
This research study collects blood, urine, and other samples from healthy volunteers to support medical research. Depending on the type of sample, you may donate blood, provide skin samples, or participate in other non-invasive procedures. Your samples help scientists understand health and develop new treatments.
Bethesda, MarylandAges 18–85
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Common questions
- Are there clinical trials for bone diseases, infectious?
- Yes. Clin2 currently lists 32 recruiting bone diseases, infectious studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bone diseases, infectious trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bone diseases, infectious trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.