Clinical trials
Brain Tumor clinical trials
Below are recruiting brain tumor clinical trials, each written for real people, not researchers. We’re tracking 270 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04222062RecruitingPhase 2
Compare Gliadel implant versus focused brain radiation
This Phase 2 study compares two ways to treat brain metastases: a Gliadel wafer placed during planned surgery versus focused stereotactic radiosurgery. It aims to see which approach works better and is safer for people with a limited number of brain tumor spots.
Detroit, MichiganAges 18 years+ - NCT05484245Recruiting
Ultrasound-guided surgery for certain brain mass lesions
This trial looks at using real-time ultrasound to help surgeons remove or treat certain brain growths and bleeding areas. It may help by making the procedure more precise for newly diagnosed cases in the upper part of the brain.
MoscowAges 18–100 - NCT05553899Recruiting
PET-MRI scans for monitoring children’s brain tumor return
This study checks whether a special scan called PET-MRI can better tell if a child’s brain tumor has come back after treatment. It may help doctors decide faster and more accurately when changes seen on regular MRI are true tumor recurrence.
Sheffield, South YorkshireAges 8–18 - NCT06146725Recruiting
Resection vs. biopsy in high-grade glioma patients
This study compares whether having surgery to remove as much of the tumor as possible (resection) or just taking a small sample (biopsy) leads to better outcomes for people with a fast-growing brain tumor (high-grade glioma). The goal is to help guide treatment decisions.
San Francisco, CaliforniaAges 18–90 - NCT06362304Recruiting
New SPECT imaging for brain tumors
This trial tests a new imaging agent (99mTc-CNDG) to see if it can help doctors see brain tumors better on a SPECT/CT scan. It might provide more information than standard scans and could help guide treatment decisions.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06810336RecruitingEarly Phase 1
Pain control after brain surgery: methadone vs remifentanil
This trial compares two medicines, methadone and remifentanil, to see which one works better for pain after brain surgery. It may help improve your recovery and comfort.
Charlottesville, VirginiaAges 18–65 - NCT07236840Recruiting
Remote neurological exams via smartphone for brain tumor patients
This trial tests if a smartphone app can help patients or caregivers perform a neurological exam at home. It aims to make check-ups easier for people with brain tumors.
Mumbai, MaharashtraAges 5 years+ - NCT05978557Recruiting
Brain tumor drug testing using live tissue samples
This trial uses a small piece of your brain tumor after surgery to test which drugs might work best for you. It helps doctors find the most effective treatment for your specific tumor.
Chapel Hill, North CarolinaAges Any age - NCT07374692Recruiting
Study of treatments for advanced brain and spinal cord tumors
This study looks at how different treatments work for people with advanced brain or spinal cord tumors that have come back. It helps doctors learn more about these tumors and how to better treat them.
Bethesda, MarylandAges 15–120 - NCT06981156Recruiting
Study of pediatric brain and spine tumor exams
This study tests a shorter way to check the brain and nervous system in children with brain or spine tumors. It aims to see if the new exam is as good as the standard one.
Madison, WisconsinAges 1–17 - NCT03526822Recruiting
Study of new glioblastoma using MRI scans and lab markers
This study follows people newly diagnosed with glioblastoma to see how certain lab signals (MMP2 and MMP9) match up with MRI scan features. It may help doctors better understand the disease and how it appears on imaging, but it’s mainly observational.
MarseilleAges 18 years+ - NCT05477680Recruiting
Measuring brain shift during surgery using navigation
This study tests whether a special brain-navigation method can better measure how the brain moves during surgery for certain brain conditions. If it works, it may help surgeons avoid mistakes caused by brain shifting while you are under anesthesia.
MoscowAges 18–100 - NCT05733312Recruiting
Ultrasound treatment to temporarily open the brain blood barrier
This study looks at using focused ultrasound to temporarily loosen the brain’s “blood barrier” around certain brain tumors, while people still get standard surgery. It aims to help doctors learn how safe the approach is and collect blood/fluid samples during the operation.
Rochester, MinnesotaAges 18 years+ - NCT07396896Recruiting
A study on brain tumors and weight gain after treatment
This trial tests a diet therapy for young people who have gained a lot of weight after treatment for a certain type of brain tumor. The goal is to see if the diet can help manage obesity related to the tumor or its treatment.
Florence, FlorenceAges 7–30 - NCT06273176Recruiting
Surgery with or without brain mapping for recurrent glioblastoma
This study is testing whether using a special brain-mapping technique during surgery helps people with recurrent glioblastoma. It compares standard surgery to surgery with mapping to see if it leads to better outcomes for tumors near important brain areas.
San Francisco, CaliforniaAges Up to 90 years - NCT07339085Recruiting
Advanced MRI for brain tumor recurrence or radiation damage
This study uses advanced MRI scans to better tell the difference between a returning brain tumor and radiation injury. It may help guide your treatment decisions.
Los Angeles, CaliforniaAges 18 years+ - NCT05139277Recruiting
Using a imaging system during brain tumor surgery
This study tests the CONVIVO system to help surgeons see certain brain tumors during surgery. It may help make operations safer and more effective by improving how tumors are identified.
Lebanon, New HampshireAges 18 years+ - NCT05556473RecruitingPhase 1
Tryptophan PET/CT scan study for different tumors
This early-phase study tests a special PET/CT scan using labeled tryptophan to help doctors see how different tumors behave. The goal is to learn whether this scan can better identify and measure cancers in the brain or elsewhere.
Detroit, MichiganAges 18 years+ - NCT05549024RecruitingEarly Phase 1
PET/CT scan study for certain prostate, brain, or breast cancers
This early-phase study tests special PET/CT scans using a radioactive tracer to see cancer areas that have specific targets. It may help doctors better visualize tumors and plan next steps, using scans that you may already be familiar with (FDG) plus targeted tracers.
BeijingAges 18 years+ - NCT05775458Recruiting
Study of treatments for aggressive brain tumor cell damage
This study looks at glioblastoma (GBM), a very aggressive brain tumor, and how “brain cell overload” (glutamate excitotoxicity) may affect tumor growth. It focuses on adults who are planned for complete tumor removal, followed by standard radiation and chemotherapy.
Milan, MilanAges 18 years+ - NCT05859659Recruiting
Hope HOPE study for glioma using pathology and MRI
This study looks at glioma (a type of brain tumor) and uses brain tissue testing, MRI scans, and related measurements to better understand the disease. You may benefit by being closely assessed with MRI and study follow-up, though it’s not necessarily testing a new medicine based on the listed criteria.
Beijing, Beijing MunicipalityAges 18–90 - NCT07511933Recruiting
New PET scan to detect tumor regrowth vs. scar tissue in brain
This study tests a new type of PET scan (a special imaging test) that uses a radioactive tracer to help doctors tell the difference between scar tissue from past radiation and cancer that has come back in the brain. This could help avoid unnecessary surgery or additional treatment.
AmsterdamAges Any age - NCT05106296RecruitingPhase 1
Chemo-immunotherapy with ibrutinib and indoximod for pediatric brain tumors
This Phase 1 study tests a combination treatment (ibrutinib plus indoximod along with chemotherapy) for children with brain tumors that have come back or are hard to treat. It may help shrink active tumor or control the disease when standard treatments can’t cure it.
Augusta, GeorgiaAges 3–25 - NCT06776250RecruitingPhase 2
Tarlatamab for IDH-mutant brain tumors
This trial tests whether a new drug called tarlatamab is safe and effective for people with certain types of brain tumors that have an IDH mutation. You may be eligible if you have had up to 2 prior treatments after the tumor returned, and you are either having surgery to remove the tumor or the tumor cannot be removed.
Toronto, OntarioAges 18 years+
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Common questions
- Are there clinical trials for brain tumor?
- Yes. Clin2 currently lists 270 recruiting brain tumor studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain tumor trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain tumor trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.