Clinical trials
Brain Tumor clinical trials
Below are recruiting brain tumor clinical trials, each written for real people, not researchers. We’re tracking 269 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07416188RecruitingPhase 1/Phase 2
LMP744 drug for returning glioblastoma
This trial tests an experimental drug called LMP744 for people whose glioblastoma has come back. It aims to see if the drug can slow or stop tumor growth by targeting specific proteins in cancer cells.
Bethesda, MarylandAges 18–99 - NCT06465199RecruitingPhase 1/Phase 2
Eflornithine and AMXT 1501 for Advanced Childhood Cancers
This trial tests a combination of two drugs (eflornithine and AMXT 1501) for children and young adults with certain types of cancer that have relapsed or not responded to standard treatment, or for a specific brain tumor (DIPG) at diagnosis. The goal is to see if this drug pair is safe and effective.
Birmingham, AlabamaAges Up to 26 years - NCT03175224RecruitingPhase 2
Test drug APL-101 for lung or other tumors with MET changes
This Phase 2 study tests APL-101 to shrink advanced cancers that have certain MET-related changes, including specific MET mutations, MET gene amplification, or MET fusions. It may help people whose tumors have run out of standard treatment options.
Los Angeles, CaliforniaAges 18 years+ - NCT04099797RecruitingPhase 1
CAR T therapy for certain GD2 brain tumors
This Phase 1 study tests CAR T cells designed to target a marker called GD2 on brain tumors. It aims to see if the treatment is safe and whether it can shrink or control these tumors in children and young adults.
Houston, TexasAges 1–25 - NCT06051240RecruitingPhase 2
Lithium to prevent thinking problems after brain radiation
This study tests if the drug lithium can help prevent memory and thinking problems that sometimes happen after brain radiation for a brain tumor. You may qualify if you are under 18 when treated and had radiation within the last 7 years.
Solna, Stockholm CountyAges 5 years+ - NCT05331521RecruitingPhase 3
Study to improve brain function in newly diagnosed glioma patients
This Phase 3 study tests a treatment plan after surgery to improve brain function and quality of life in adults with newly diagnosed, specific types of brain tumors (gliomas). It may help you keep thinking clearly and living better while your tumor is treated with standard medicines.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT04135807RecruitingEarly Phase 1
Implantable device test for operable brain tumor patients
This early-phase trial tests a tiny implanted device placed during brain tumor surgery. It delivers very small doses of medicine directly to the tumor area for a short time, aiming to see if this approach is safe and workable in patients with certain gliomas.
Boston, MassachusettsAges 18 years+ - NCT06449989Recruiting
Comparing genetics of colorectal cancer and its brain spread
This study compares the genetics of the original colorectal cancer with the cancer that has spread to the brain. It aims to understand how the tumor changes when it metastasizes, which may help guide future treatments.
Moscow, MoscowAges 18 years+ - NCT06673329RecruitingPhase 1
Brodalumab for immune-related side effects from cancer treatment
This trial tests if brodalumab, an antibody that blocks a specific immune pathway (IL-17), can help control side effects caused by immunotherapy cancer treatment. It is for people with advanced solid organ cancers who have immune-related side effects that are suspected to involve IL-17.
New York, New YorkAges 18 years+ - NCT07441421Recruiting
Improved pain relief for brain tumor surgery
This study tests a combination of pain-relief methods given before, during, and after brain surgery to see if they better control pain and help you recover with fewer side effects. It's for adults having surgery to remove a brain tumor.
BeijingAges 18–65 - NCT07831772Recruiting
Maintenance radiotherapy for newly diagnosed glioblastoma
This study tests an extra course of radiation therapy after standard treatment for glioblastoma, a type of brain cancer. The goal is to see if it helps keep the cancer from coming back.
Minneapolis, MinnesotaAges 18 years+ - NCT07805096Recruiting
Smart health app for children with cancer and their parents
This study tests a smart health app designed to support the mental, physical, and spiritual well-being of children with leukemia or a brain tumor and their parents. It aims to see if the app helps improve overall health and quality of life.
TaipeiAges 7 years+ - NCT06623565Recruiting
Advanced imaging for extensive brain tumor removal
This trial uses advanced imaging to help surgeons remove as much of a malignant brain tumor as safely possible. It may be a good fit if you have a new diagnosis of glioblastoma or a certain astrocytoma and are healthy enough for surgery.
Amsterdam, North HollandAges 18 years+ - NCT07627334Recruiting
Personalized drug testing for newly diagnosed brain tumors
This trial tests whether customized drug screening on your tumor cells can help doctors choose the best treatment for you. Your tumor cells will be grown in the lab and tested against different drugs to find what works best, combined with short-course radiation therapy.
Vienna, State of ViennaAges Any age - NCT05528939Recruiting
Training attention skills for children after cancer
This trial tests a computer-based “attention-control training” program to see if it’s doable and helpful for children who finished treatment for acute lymphoblastic leukemia or a brain tumor. It also looks at how acceptable the program is for both kids and caregivers.
Washington D.C., District of ColumbiaAges 8–16 - NCT05968053Recruiting
Testing microplastics detection in neurosurgery patients
This study checks whether microplastics and nanoplastics can be detected in people undergoing neurosurgery. If it works, it could help doctors better understand possible material exposures around brain and nerve procedures.
Beijing, Beijing MunicipalityAges 18–80 - NCT06710249RecruitingPhase 2
Testing Salovum and SPC Flakes for Brain Tumor Swelling
This trial tests whether two special food products (Salovum and SPC Flakes) can help reduce brain swelling caused by tumors. If you have a brain tumor with swelling and are already on steroids, you may be able to join.
LundAges 18–79 - NCT07460037Recruiting
Brain signal study for speech recovery after stroke or injury
This trial uses a special brain-mapping test called high-density ECoG to study how people who have lost speech due to stroke, brain tumor, or ALS can be helped by reading brain signals when they imagine speaking. It may lead to new devices that let people with severe speech problems communicate using only their thoughts.
Hangzhou, ZhejiangAges 20–80 - NCT07446842Recruiting
AI model for better diagnosis of brain diseases
This study is building an artificial intelligence system to improve how doctors diagnose brain conditions using scans like MRI. If you are diagnosed with one of the listed conditions, your scans and medical information may help train the AI.
Wuhan, HubeiAges Any age - NCT04066465Recruiting
Testing how proton therapy affects thinking in young people
This study looks at how proton radiation therapy may affect thinking, learning, and brain function in children and teens with a primary brain tumor. It uses repeated short brain/learning tests to track possible changes over time.
Dresden, SaxonyAges 8–18 - NCT06164314Recruiting
Calming medicine during brain tumor surgery
This trial tests if a calming medicine (dexmedetomidine) given during and after brain tumor surgery can help prevent confusion or delirium afterwards.
BeijingAges 18 years+ - NCT05274919Recruiting
Brain tumor MRI pattern study to map tumor genetics
This study uses special “pattern mapping” from brain MRI scans to see whether MRI images reflect a brain tumor’s genetic type. It may help doctors better match MRI findings to tumor characteristics using scans they may already need for diagnosis.
LeidenAges 18 years+ - NCT07321353Recruiting
Survivors Journey+: Support for brain tumor survivors
This study looks at how to support children and teens who have finished treatment for a brain tumor. It may help families find ways to cope and thrive after cancer therapy.
Cincinnati, OhioAges 15–25 - NCT07271966Recruiting
Vitamin B6 for Keppra side effects in brain tumor patients
This trial tests whether vitamin B6 can help reduce mood and behavior side effects of levetiracetam (Keppra) in people with brain tumors and seizures. If you're taking Keppra and feeling down or distressed, this study might offer a way to feel better.
Durham, North CarolinaAges 18 years+
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Common questions
- Are there clinical trials for brain tumor?
- Yes. Clin2 currently lists 269 recruiting brain tumor studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain tumor trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain tumor trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.