Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,062 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06742450Recruiting
Comparing two ways to stimulate the brain for Parkinson's
This trial compares two methods of deep brain stimulation (constant current vs constant voltage) for people with Parkinson's who already have the device placed but haven't turned it on yet. The goal is to see which method works better.
BeijingAges 18–75 - NCT05648812RecruitingPhase 3
Ultrasound tests for baby brains using special imaging
This Phase 3 study tests whether detailed ultrasound scans (with contrast and stiffness measurements) can help doctors assess a baby’s brain. It may help by improving how early brain changes are detected in newborn care settings.
Turku, Southwestern FinlandAges 1 minute–6 months - NCT07327710Enrolling by invitation
Brain-Computer Interface and Electrical Stimulation for Facial Paralysis
This trial tests a non-invasive treatment that combines a brain-computer interface with mild electrical stimulation to help people with one-sided facial paralysis regain movement. It aims to improve facial muscle function by retraining the brain and muscles together.
Changzhou, JiangsuAges 18–75 - NCT07177781Recruiting
Blueberries and brain function in older adults
This study tests whether eating wild blueberries every day for several weeks can improve brain function in people ages 60 to 75 who are overweight or obese. You'll eat blueberry powder or a placebo and have memory and thinking tests before and after.
Maastricht, LimburgAges 60–75 - NCT07057245Recruiting
Protein supplement and brain function in older adults
This study tests whether taking a daily protein supplement can improve how your brain works. It is for healthy older adults (ages 60–75) who are overweight but do not have diabetes or take certain medications.
Maastricht, LimburgAges 60–75 - NCT06910293Recruiting
Brain Activity During Menstrual Cycle vs. Fertility Treatment
This study looks at how natural menstrual cycles and ovarian stimulation (which mimics some fertility treatments) affect brain activity and hormone levels. Researchers want to understand normal brain changes during the cycle to help improve fertility treatments.
Abu Dhabi, Abu Dhabi EmirateAges 25–35 - NCT06813300Recruiting
Brain signals during deep brain stimulation for thinking or moving tasks
This study looks at how brain signals change during deep brain stimulation (DBS) when you are thinking or moving. It aims to find better ways to see if DBS is working by recording your brain's electrical activity.
GrenobleAges 18 years+ - NCT07209683Recruiting
Near-infrared light therapy for brain function in adults
This study tests whether shining a special near-infrared light on the head can improve how well your brain works and how clearly you think. It is for healthy younger and older adults who want to help find new ways to support brain health.
Oklahoma City, OklahomaAges 21–85 - NCT07058428RecruitingPhase 3
FSRT with Avastin for multiple brain tumors from lung cancer
This trial tests giving focused radiation (FSRT) along with Avastin (bevacizumab) to people with multiple brain metastases from lung adenocarcinoma. It aims to see if combining these treatments is safe and effective for tumors that are too large or numerous for standard one-time radiation.
Guangzhou, GuangdongAges 18 years+ - NCT07422220Recruiting
Walnuts and brain health: a long-term study
This study tests whether eating walnuts every day for a long time can help keep your brain healthy as you age. It is for middle-aged and older adults who carry extra weight around their belly but are otherwise generally healthy.
Maastricht, LimburgAges 45–75 - NCT07719595Recruiting
Vagus nerve stimulation for coma after brain injury
This trial tests if a gentle electrical stimulation of the vagus nerve (a nerve in the neck) can help people regain consciousness after a severe traumatic brain injury. It is for patients who are in a coma or minimally conscious state, and the treatment is given along with standard ICU care.
Stony Brook, New YorkAges 18 years+ - NCT02896335RecruitingPhase 2
Palbociclib and pembrolizumab for brain metastases
This study tests two drugs, palbociclib and pembrolizumab, for people whose solid tumors (like breast cancer or melanoma) have spread to the brain. The goal is to see if this combination can shrink or slow the growth of brain tumors that are progressing despite prior treatment.
Boston, MassachusettsAges 18 years+ - NCT03053791Recruiting
Deep brain stimulation to improve walking after incomplete spinal injury
This study tests whether deep brain stimulation can improve walking in people with an incomplete spinal cord injury. It also requires that you meet specific injury and walking ability requirements and be able to attend study visits and training.
ZurichAges 18–75 - NCT03550391RecruitingPhase 3
Surgery-like brain radiation vs avoiding the memory center
This trial compares two ways of giving radiation to the brain for people with 5 or more brain metastases: focused stereotactic radiosurgery, or a whole-brain approach that tries to spare the memory area (with memantine). It aims to see which method better protects thinking and memory while still treating the tumors.
Tucson, ArizonaAges 18 years+ - NCT03592563Recruiting
Brain health follow-up study for adults
This study follows adults over time to better understand brain health and brain-related conditions. You may join if you already have certain neurological or psychiatric diagnoses, are at higher risk, or simply want to help research on maintaining brain health.
Hong KongAges 18 years+ - NCT03684109Recruiting
MRI scans to study brain tumors using molecular imaging
This study uses special MRI scans to better “characterize” (study) gliomas, a type of brain tumor, using information from your brain tissue. You may be eligible if you’re an adult with a suspected or confirmed glioma and you already need a biopsy or surgery.
Miami, FloridaAges 18 years+ - NCT03823144Recruiting
Imaging small live tumor details during surgery
This study uses a special camera to look at solid tumors from inside the body during an operation. It tests whether “live” tumor imaging (using a medicine called fluorescein) can be safely performed in people with certain solid cancers.
Jacksonville, FloridaAges 18 years+ - NCT03952962Recruiting
Brain stimulation trial for depression that hasn’t improved
This trial tests a targeted deep brain stimulation procedure to reduce symptoms in people with long-lasting, treatment-resistant depression. It may help by improving mood symptoms using stimulation guided by detailed brain imaging.
Dallas, TexasAges 21–70 - NCT04006561Recruiting
Brain lymphoma study using targeted whole-brain radiation
This trial studies how newly diagnosed primary central nervous system (brain) non-Hodgkin lymphoma responds to a specific type of radiation to the whole brain, and it also looks at changes in thinking, mood, and behavior. It may help doctors understand how this treatment affects day-to-day brain function.
TaoyuanAges 18–80 - NCT04135807RecruitingEarly Phase 1
Implantable device test for operable brain tumor patients
This early-phase trial tests a tiny implanted device placed during brain tumor surgery. It delivers very small doses of medicine directly to the tumor area for a short time, aiming to see if this approach is safe and workable in patients with certain gliomas.
Boston, MassachusettsAges 18 years+ - NCT04197297RecruitingPhase 2
Brain scan tests for biomarkers in people with brain metastases
This trial studies brain scan findings to see if specific imaging markers can help understand or predict outcomes in people with brain metastases. It may help researchers improve how brain metastases are evaluated before radiation treatment.
Toronto, OntarioAges 18 years+ - NCT04343157RecruitingPhase 2
Image-guided focused radiation to protect thinking in brain metastases
This Phase 2 trial tests a brain radiation technique that aims to treat up to a few brain metastases while sparing areas important for thinking and memory. It may help people keep cognitive abilities better than with more brain-wide radiation approaches.
San Diego, CaliforniaAges 18 years+ - NCT04708613Recruiting
Brain testing study for former football players and controls
This study looks at how the brain and thinking may be affected by playing professional football, using brain scans and thinking tests. It also compares former players with similar men who did not play organized football beyond high school.
Pittsburgh, PennsylvaniaAges 29–59 - NCT04806620Recruiting
Online app study for brain inflammation lifestyle data
This study uses a digital platform (app/website) to collect lifestyle and symptom information to better understand brain inflammation. You may qualify if you have certain conditions like Long COVID, migraines, autoimmune disease, inflammatory gut issues, mood disorders, or if you are a healthy comparison person.
Delafield, WisconsinAges 2 years+
Hear when a new Brain trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,062 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.