Clinical trials
Brain clinical trials
Below are recruiting brain clinical trials, each written for real people, not researchers. We’re tracking 2,063 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04427384Recruiting
Brain tumor patients treated with GammaTiles registry
This study is a patient registry for people with brain tumors who had surgery to remove as much as safely possible and then had GammaTiles placed. It mainly collects information and follow-up imaging to understand how patients do after the treatment.
Phoenix, ArizonaAges Any age - NCT07577336Recruiting
Portable MRI for brain injury in children
This study tests whether a small, portable MRI machine can take pictures of the brain at the bedside for children with brain injuries from lack of oxygen or blood flow. It may help doctors see the injury sooner and guide care without moving the child.
Kansas City, MissouriAges Up to 17 years - NCT04899908RecruitingPhase 2
Brain radiation with or without gadolinium nanoparticles for brain metastases
This trial tests whether adding tiny gadolinium-containing nanoparticles to standard brain radiation can better control brain metastases from certain cancers. It is for people with tumors that have grown after immunotherapy, are from certain cancers (like melanoma, GI, or HER2+ breast), are cystic, are large, or have come back after prior radiation.
Boston, MassachusettsAges 18 years+ - NCT07132190RecruitingPhase 2
Radiation for growing brain tumors with same-day planning
This study tests whether a precise, one-day radiation treatment for brain tumors that are growing or in tricky spots can be effective with a smaller safety margin. It's designed for people whose brain tumors are changing quickly or sitting near areas of swelling or recent surgery.
Boston, MassachusettsAges 18 years+ - NCT06480838Recruiting
Brain blood flow and thinking after traumatic brain injury
This study looks at how the brain controls its own blood flow after a moderate to severe traumatic brain injury (TBI). It uses MRI scans and thinking tests to understand recovery and help improve care for people like you.
Dallas, TexasAges 18–80 - NCT07248228RecruitingPhase 2
Memory-sparing vs standard whole brain radiation for brain metastases
This trial compares two types of whole brain radiation for people with many brain tumors. One method tries to protect parts of the brain important for memory, while the other does not. It aims to see which approach helps maintain thinking and memory better.
Cleveland, OhioAges 18 years+ - NCT03213002RecruitingPhase 1/Phase 2
CAPTEM pills after brain radiation for newly diagnosed glioblastoma
This trial studies whether taking two chemotherapy pills (capecitabine and temozolomide) after the initial 6-week radiation-and-chemo phase can help people with newly diagnosed glioblastoma. It aims to test safety and early effectiveness right before the usual maintenance temozolomide phase.
New York, New YorkAges 18–74 - NCT04331392Recruiting
Online memory training for people with recent brain injury
This trial tests an online memory program for people with a recent traumatic brain injury (TBI) to help with thinking and memory. It may be useful if your injury is recent and you can safely do MRI scanning.
Toronto, OntarioAges 18–55 - NCT05023434Recruiting
Brain stimulation study for hand strength in brain tumor patients
This study uses brain stimulation during surgery to see how it affects hand strength and hand function. It may help doctors understand which brain areas are important for hand movement in people with certain brain tumors.
Milwaukee, WisconsinAges 18–75 - NCT05559853Recruiting
MRI scan study to track brain tumor changes after treatment
This study tests a new MRI (brain scan) method to see how brain tumors change over time after treatment. There are also parts for healthy adults to help with developing and comparing the scan technique.
New York, New YorkAges 18 years+ - NCT05843084Recruiting
7-Tesla brain scans to map networks for Parkinson’s DBS
This study uses a very strong MRI (7-tesla) to analyze how parts of the brain connect in people with Parkinson’s who already have deep brain stimulation (DBS). It may help researchers better understand DBS and how it works in the brain.
Amsterdam, North HollandAges 18 years+ - NCT06273176Recruiting
Surgery with or without brain mapping for recurrent glioblastoma
This study is testing whether using a special brain-mapping technique during surgery helps people with recurrent glioblastoma. It compares standard surgery to surgery with mapping to see if it leads to better outcomes for tumors near important brain areas.
San Francisco, CaliforniaAges Up to 90 years - NCT06413173Recruiting
Remote brain stimulation for attention after mild TBI
This trial tests if a remote brain stimulation device can improve attention and concentration in active-duty service members who have had a mild traumatic brain injury. Participants use the device at home while completing tasks to help with daily focus.
San Diego, CaliforniaAges 18–60 - NCT06930846Recruiting
Brain cancer cognitive training study
This study tests a home-based program called HOBSCOTCH-CA to help with memory and thinking problems after brain cancer treatment. The program uses phone and internet sessions to teach self-management skills.
Lebanon, New HampshireAges 18 years+ - NCT07126821Recruiting
Brain disease diagnosis study using vision and language
This trial tests a new computer model that combines brain MRI scans and clinical data to help diagnose brain diseases. It may help doctors make more accurate diagnoses.
Changsha, HunanAges Any age - NCT07341230Recruiting
Deep brain stimulation for alcohol addiction
This trial tests if deep brain stimulation can help people with severe alcohol addiction who haven't been helped by other treatments. It involves implanting a device to stimulate brain areas linked to addiction.
Cambridge, CambridgeshireAges 18–60 - NCT02754544Recruiting
Brain mapping during tumor surgery while you are awake
This study uses special recording sensors during brain tumor surgery to map the brain areas that control movement and speech. It may help the surgical team protect these key functions while removing the tumor.
Houston, TexasAges 18 years+ - NCT02800486RecruitingPhase 2
Targeted antibody plus repeat radiation for recurrent brain tumors
This trial studies giving cetuximab (a targeted antibody) directly into an artery along with repeat radiation to treat certain recurring or treatment-resistant brain tumors. It may help by delivering the drug more directly to tumor areas and testing whether this approach can control the disease after it comes back.
New York, New YorkAges 18 years+ - NCT07410598Recruiting
Testing a new way to use deep brain stimulation at home
This study tests a new type of brain stimulation called patterned stimulation for people with Parkinson's who already have a deep brain stimulation (DBS) device. It aims to see if using this special stimulation at home is safe and comfortable.
Gainesville, FloridaAges 18–80 - NCT07505173RecruitingPhase 2
Targeted radiation plus osimertinib for brain metastases from EGFR-mutant lung cancer
This trial tests adding a brain-sparing radiation technique to the targeted therapy drug osimertinib for people with EGFR-mutant lung adenocarcinoma that has spread to the brain and is causing symptoms. The goal is to see if this combination can better control the brain tumors while protecting the hippocampus, a key memory area.
TianjinAges 18–75 - NCT07509125Recruiting
Ultra-high resolution PET brain scans for aging, dementia, and psychosis
This study uses a new ultra-high resolution PET scanner to look at brain changes in healthy aging, dementia, ALS, movement disorders, and psychosis. It aims to better understand these conditions and improve imaging techniques.
Leuven, Vlaams-BrabantAges 18–90 - NCT05317858RecruitingPhase 3
Open the brain’s blood barrier to treat lung cancer brain spots
This trial tests whether using focused ultrasound to temporarily open the brain’s blood barrier—plus standard immune therapy—can better treat non-small cell lung cancer (NSCLC) that has spread to the brain. It aims to help medicines reach the brain tumor spots more effectively, while still using the usual lung cancer treatment.
Phoenix, ArizonaAges 18–100 - NCT05912270Recruiting
Music lessons to boost thinking skills in primary school
This trial studies whether an “orchestra in class” music program can improve kids’ thinking and brain development. It’s meant for younger primary school children and may help with skills like planning and attention.
GenevaAges 6–8 - NCT07443397RecruitingPhase 3
Anlotinib plus whole-brain radiation for SCLC brain metastases
This trial tests whether combining Anlotinib (a targeted drug that blocks tumor blood vessel growth) with whole-brain radiation can better control brain metastases in small cell lung cancer patients. It is for people with up to 10 brain tumors who have not had brain radiation before.
Beijing, Beijing MunicipalityAges 18–80
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Common questions
- Are there clinical trials for brain?
- Yes. Clin2 currently lists 2,063 recruiting brain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a brain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a brain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.