Clinical trials
Breast Cancer Surgery clinical trials
Below are recruiting breast cancer surgery clinical trials, each written for real people, not researchers. We’re tracking 1,160 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06402435RecruitingPhase 2
Combination therapy before surgery for hormone positive breast cancer
This trial tests a new combination of treatments given before surgery for hormone receptor positive, HER2 negative breast cancer. It uses stereotactic body radiation therapy (SBRT), chemotherapy, and an investigational drug called AK112 to shrink tumors and make surgery easier.
Wuhan, HubeiAges 18 years+ - NCT06860815RecruitingPhase 2
Cemiplimab with liver radiation for breast cancer that spread to the liver
This trial tests a combination of a drug called cemiplimab (an immunotherapy that helps your immune system fight cancer) and a type of targeted radiation (Y-90 SIR-Spheres) given directly to liver tumors. It is for people with breast cancer that has spread to the liver and who have already had at least one type of chemotherapy.
Duarte, CaliforniaAges 18 years+ - NCT06858449Recruiting
Exercise and protein during chemo for breast cancer
This study tests whether adding resistance training (like lifting weights) along with a protein shake after workouts can help women with breast cancer maintain muscle and bone health while they receive chemotherapy before surgery.
Pittsburgh, PennsylvaniaAges 20–89 - NCT05233891Recruiting
Swedish-language study of scales used in breast reconstruction
This study checks whether certain rating tools (called “scales”) are working well for people having breast reconstructive surgery at Sahlgrenska University Hospital. It may help future patients because it improves how outcomes and symptoms are measured in the clinic.
GothenburgAges 18–100 - NCT06833502RecruitingPhase 2
Screening for breast cancer spread after chemo and surgery
This trial aims to find out if doing special scans to check for breast cancer spread to organs (not just lymph nodes) is helpful in certain patients. The study looks at people with breast cancer that had already spread to lymph nodes and did not completely go away with chemotherapy and surgery.
Tampa, FloridaAges 18 years+ - NCT06817954Recruiting
Breast reconstruction after mastectomy for breast cancer
This trial tests how safe and effective it is to remove the breast (mastectomy) and rebuild it right away during the same surgery. It is for women with early-stage breast cancer who want reconstruction instead of breast-sparing surgery.
Nanjing, JiangsuAges 18–75 - NCT06807749Recruiting
Adjuvant treatment for premenopausal breast cancer
This trial looks back at premenopausal women with early-stage, hormone-positive, HER2-negative breast cancer who had surgery and an Oncotype DX test, to see how different treatments affected their outcomes. If you fit this group, your past medical records could help researchers learn more about the best treatments.
Roma, Antonella PalazzoAges Up to 60 years - NCT06797635RecruitingPhase 2
Study of Patritumab Deruxtecan and Pembrolizumab for High-Risk Early Breast Cancer
This trial tests a combination of targeted therapies (patritumab deruxtecan plus pembrolizumab) along with other anticancer drugs for people with a high-risk type of early-stage breast cancer that is either triple-negative or has very low hormone receptors and is HER2-negative. The goal is to see if this approach can help prevent the cancer from coming back.
Santa Monica, CaliforniaAges 18 years+ - NCT06799065RecruitingPhase 1/Phase 2
Oral drug for advanced solid tumors including ovarian cancer
This trial tests a new daily pill that targets a protein helping cancer cells divide. It may stop tumors from growing in people with advanced or metastatic cancer that has returned or stopped responding to standard treatments, including some types of ovarian, lung, and other solid tumors.
Aurora, ColoradoAges 18 years+ - NCT06174363Recruiting
Pain Relief Study for Breast Cancer Surgery
This study tests a combination pain medicine (Maxigesic) to see how well it controls pain after breast cancer surgery. It may help you need fewer opioids after your operation.
SeoulAges 20–70 - NCT06787339RecruitingPhase 2
Capecitabine for low-risk triple negative breast cancer
This trial tests whether a chemotherapy pill called capecitabine can help people with low-risk triple negative breast cancer after surgery. It is for patients with stage I disease who have certain features that suggest a lower chance of recurrence.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06788834Recruiting
Pre-surgery exercise and nutrition program for cancer patients
This trial tests a program of exercise and nutritional support before cancer surgery to help you recover faster. It is for patients having major abdominal, chest, or gynecologic cancer surgery.
Catanzaro, ItalyAges 18 years+ - NCT05035745RecruitingPhase 1/Phase 2
Selinexor plus talazoparib for advanced triple-negative breast cancer
This trial tests selinexor plus talazoparib in people with advanced, treatment-resistant solid tumors and, separately, advanced triple-negative breast cancer. It aims to see whether this combination can shrink tumors or slow their growth when standard options have not worked.
SingaporeAges 18–99 - NCT06765590Recruiting
Paclitaxel (albumin-bound) bioequivalence study in breast cancer
This study tests whether a new version of paclitaxel (albumin-bound) works the same as the approved version in people with breast cancer. It's for patients whose cancer has spread or returned after other treatments, or those for whom this drug is recommended by treatment guidelines.
Luoyang, HenanAges 18–75 - NCT06761196Recruiting
Quality of life after breast cancer surgery
This study looks at how breast cancer surgery affects your quality of life. It includes people with any stage of breast cancer (or at high risk) who need breast surgery under general anesthesia. The goal is to learn how to better support your recovery and well-being.
ColmarAges 18 years+ - NCT06768268Enrolling by invitationPhase 1/Phase 2
Better lymph node imaging for breast cancer
This trial tests whether adding two common fluids (Mannitol and Voluven) before an ICG dye injection can help surgeons better see the lymph nodes that need to be removed during breast cancer surgery. It aims to make sentinel lymph node biopsies more accurate and safer.
Hsinchu CountyAges 20–70 - NCT06744465Recruiting
Light-based monitoring for breast cancer during chemo
This study uses a special light-based device to monitor breast cancer during chemotherapy before surgery. It is for women with HER2-positive or triple-negative breast cancer who are planning chemotherapy first.
Indianapolis, IndianaAges 18 years+ - NCT06748222RecruitingPhase 3
Online mindfulness program for breast cancer survivors
This trial tests a 6-week online mindfulness program to help breast cancer survivors manage mild to moderate depression. You may qualify if you finished active treatment within the last 5 years and can use a digital device.
Phoenix, ArizonaAges 18–50 - NCT06738654Recruiting
Robotic breast-conserving surgery through the armpit for early-stage breast cancer
This trial tests a new robotic technique for removing early-stage breast cancer through the armpit, leaving no scar on the chest. It may be an option for women who want to keep their breast shape and avoid visible scarring.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT06723990Recruiting
HER2 breast cancer treatment decision study
This study tests a tool called HER2DX to help doctors choose the best treatment for early stage HER2 positive breast cancer. It may help tailor therapy before or after surgery.
Milan, ItalyAges 18 years+ - NCT06716073Recruiting
Endoscopic vs standard breast-conserving surgery after chemo
This study compares two types of breast-conserving surgery for women who have already had chemotherapy before their operation. It aims to see if using a tiny camera (endoscope) leads to equally good long-term results as standard breast-conserving surgery.
Guangzhou, GuangdongAges 18–75 - NCT06715826RecruitingPhase 1/Phase 2
Imaging breast cancer with a targeted radioactive tracer
This study is testing a new imaging method that uses a radioactive tracer to find breast cancer cells. It may help doctors see the cancer more clearly.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT03740893RecruitingPhase 2
Test drug to block DNA damage in triple-negative breast cancer
This Phase 2 trial studies a treatment given around the time of breast surgery to help shrink or control residual (remaining) triple-negative breast cancer. It also checks biomarkers (lab signals) to understand who benefits, with some people receiving anti–PD-L1 immunotherapy and some not.
Bournemouth, DorsetAges 18 years+ - NCT06694519Recruiting
Radiofrequency and exercise for pelvic floor issues after breast cancer
This trial tests whether radiofrequency therapy combined with exercise can help with pelvic floor problems like pain, urgency, or incontinence that some women have after breast cancer treatment.
Elche, Spain / ValenciaAges 18 years+
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Common questions
- Are there clinical trials for breast cancer surgery?
- Yes. Clin2 currently lists 1,160 recruiting breast cancer surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.