Clinical trials
Breast Cancer Surgery clinical trials
Below are recruiting breast cancer surgery clinical trials, each written for real people, not researchers. We’re tracking 1,193 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06524895Recruiting
Reiki for women having breast surgery
This trial tests if Reiki, a gentle hands-on relaxation technique, can improve quality of life for women undergoing mastectomy for breast cancer. If you are having a mastectomy and live near the Bronx, you may be eligible.
The Bronx, New YorkAges 18–99 - NCT06545682RecruitingPhase 1
Study of alpelisib and pembrolizumab for advanced breast cancer or melanoma
This trial tests a combination of two drugs, alpelisib and pembrolizumab, for people with advanced triple-negative breast cancer or melanoma that has spread. The goal is to see if the combination can help shrink tumors, including those that have spread to the brain.
Houston, TexasAges 18 years+ - NCT06568692RecruitingPhase 2
Study of PCS6422 with capecitabine for advanced breast cancer
This trial tests a new drug combination (PCS6422 plus capecitabine) for people with advanced or metastatic breast cancer that has not responded to other treatments. The goal is to see if adding PCS6422 can make the chemotherapy work better.
Tucson, ArizonaAges 18 years+ - NCT06568705RecruitingPhase 2
Shorter adaptive radiation for early breast cancer
This trial tests a shorter, more targeted course of daily radiation for early-stage breast cancer. The radiation plan is adjusted each day to better fit your body, which may reduce side effects.
BeijingAges 35–70 - NCT06569706Recruiting
Mastectomy with nipple preservation using endoscopy
This study tests a less invasive mastectomy for people with breast cancer. The surgery uses a small camera (endoscope) to remove breast tissue while keeping the nipple, and reconstruction is done at the same time.
MontpellierAges 20–75 - NCT06586957RecruitingPhase 1
Study of NKT3964 for advanced solid tumors
This trial is testing an experimental oral drug called NKT3964 for people with advanced solid tumors that have stopped responding to standard treatments. The drug works by blocking a protein called CDK2, which some cancers need to grow.
Little Rock, ArkansasAges 18 years+ - NCT06590727Recruiting
Emotional health in breast cancer patients
This study looks at how surgery or cancer treatments affect the emotional well-being of people with breast cancer. It aims to understand your feelings and mental health during treatment.
RomaAges 18 years+ - NCT06593132Recruiting
Single-port endoscopic breast-conserving surgery trial
This trial compares a newer, less invasive endoscopic surgery (using a single small cut) to the traditional open surgery for removing breast cancer while keeping the breast. It's for women with early-stage breast cancer who want a breast-conserving option.
Xi'an, ShaanxiAges 20–70 - NCT06595966Recruiting
Blood test study for early detection of breast cancer return
This study looks for tiny bits of cancer DNA in your blood after breast cancer surgery. A blood test called NGS may help doctors find early signs of cancer coming back, and you would give samples and have checkups for 3 years.
Hangzhou, ZhejiangAges 18 years+ - NCT06606730RecruitingPhase 3
Personalized pembrolizumab after strong chemo response for early triple-negative breast cancer
This trial is for people with early triple-negative breast cancer who had a strong response to chemotherapy combined with pembrolizumab before surgery. It aims to find the best way to continue using pembrolizumab after surgery to reduce the risk of cancer coming back.
BrusselsAges 18 years+ - NCT06608446Recruiting
Rehab from home after breast cancer surgery
This study tests a remote physical therapy program to help manage complications after breast cancer surgery. It may help you recover movement and reduce discomfort without needing to travel to a clinic.
Roma, RomaAges 18 years+ - NCT06624917Recruiting
Green breast surgery study
This study compares a new 'green' breast surgery approach (which reduces waste and uses ultrasound guidance) to standard surgery. It aims to see if the green method is as safe and effective, while also improving quality of life and lowering environmental impact.
RomaAges 18–75 - NCT06635980RecruitingPhase 2
Radiation before or after breast cancer surgery
This trial compares two ways of giving radiation for breast cancer that has not spread: before or after surgery. It aims to see if giving radiation first might work as well or better.
Scottsdale, ArizonaAges 18 years+ - NCT06637306RecruitingEarly Phase 1
Testing dupilumab with chemo for advanced triple-negative breast cancer
This trial adds dupilumab (a targeted immune treatment) to standard chemotherapy before surgery for patients with advanced triple-negative breast cancer. The goal is to see if this combination helps shrink tumors more effectively.
New York, New YorkAges 18 years+ - NCT06642545RecruitingPhase 2
New targeted drug combo for HER2-low breast cancer
This trial tests a new combination of targeted drugs (Disitamab Vedotin and RC148) against a standard chemotherapy (Abraxane) with or without an immunotherapy drug (Toripalimab) for advanced breast cancer that is HER2-low and hormone receptor-negative. The goal is to see if the new combination works better at shrinking tumors and slowing cancer growth.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06649331RecruitingPhase 2
Re-trying antibody-drug conjugates for advanced breast cancer
This study looks at whether giving a different antibody-drug conjugate (ADC) after a previous one can help people with advanced or metastatic breast cancer. It aims to find new options for patients who have already had ADC treatment.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06660628Recruiting
Radiation therapy with or without breath-hold for left breast cancer
This study compares two types of radiation therapy for left breast cancer: one using a breath-holding technique to protect the heart, and another without it. The goal is to see which is safer and more effective for women who have had surgery.
Beijing, Beijing MunicipalityAges 18–70 - NCT06694519Recruiting
Radiofrequency and exercise for pelvic floor issues after breast cancer
This trial tests whether radiofrequency therapy combined with exercise can help with pelvic floor problems like pain, urgency, or incontinence that some women have after breast cancer treatment.
Elche, Spain / ValenciaAges 18 years+ - NCT06712524Recruiting
Comparing surgery types for granulomatous mastitis
This study compares different surgical methods for treating granulomatous mastitis, a rare inflammatory breast condition. It aims to find which approach works best for patients who can safely have surgery.
Wuhan, HubeiAges 18 years+ - NCT06715826RecruitingPhase 1/Phase 2
Imaging breast cancer with a targeted radioactive tracer
This study is testing a new imaging method that uses a radioactive tracer to find breast cancer cells. It may help doctors see the cancer more clearly.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06725082RecruitingPhase 1
Collagen treatment for breast tumor surgery recovery
This trial tests if a lab-made human collagen, applied during breast tumor surgery, can improve healing and long-term outcomes. It may be an option for women who are having a needle biopsy and surgery, and have not had prior cancer treatment.
Beijing, ChinaAges 18–80 - NCT06728527Recruiting
Partial breast reconstruction with chest wall flap
This trial tests a specific type of partial breast reconstruction called a chest wall perforator flap. It's for women who previously had a lumpectomy and now want to improve the shape of their breast.
Cambridge, CambridgeshireAges 18 years+ - NCT06729684Recruiting
Digital health program for breast cancer side effects
This study is testing a personalized digital health program to help breast cancer survivors manage side effects. It uses a smartphone app to track symptoms and offer support.
Seoul, Republic of KoreaAges 18–65 - NCT06738459Recruiting
Matching lymph node tests in breast cancer
This study looks back at past MRI scans and lymph node biopsies or surgeries in people with breast cancer to better understand how cancer spreads to the lymph nodes. If you had these tests as part of your care, your data might help improve future treatment decisions.
VillachAges 18 years+
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Common questions
- Are there clinical trials for breast cancer surgery?
- Yes. Clin2 currently lists 1,193 recruiting breast cancer surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.