Clinical trials
Breast cancer clinical trials
Cancer that forms in the cells of the breast, the most common cancer in women. We’re tracking 2,470 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04354064Recruiting
Blood DNA test to see early treatment response in solid tumors
This study looks at circulating tumor DNA, which is tiny bits of DNA found in blood, to help assess how solid tumors are responding early. It uses blood samples from healthy adults who are willing to donate.
St Louis, MissouriAges 18 years+ - NCT04362826Recruiting
Trial tests a probiotic to change gut microbes in breast cancer
This study gives a probiotic to see whether it safely changes the gut’s bacteria and fungi (your “microbiome”) in people with breast cancer. The researchers want to learn if this shift in gut microbes might support breast cancer treatment or health during care.
Cleveland, OhioAges 18–65 - NCT04368702Recruiting
MRI-guided radiation for people needing radiation for cancer
This study tests whether radiation given with help from MRI (a type of scan) can better treat cancers that need radiation. You may be eligible if your cancer is confirmed and you can safely have MRI scans.
Boston, MassachusettsAges 18 years+ - NCT04430595RecruitingPhase 1/Phase 2
Modified immune cells for advanced breast cancer
This trial tests a new therapy where your immune cells are modified to better recognize and attack breast cancer cells. It is for people with advanced or recurrent breast cancer that has certain markers on the tumor cells.
Shenzhen, GuangdongAges 18–75 - NCT04434040RecruitingPhase 2
Atezolizumab and sacituzumab to prevent breast cancer return
This trial tests two medicines after surgery and chemotherapy to help lower the risk that triple-negative breast cancer comes back. It’s for people whose cancer still showed “residual” invasive disease after neoadjuvant (before-surgery) chemotherapy, and whose blood test shows traces of tumor DNA.
San Francisco, CaliforniaAges 18 years+ - NCT04478851Recruiting
Exercise program to help people live well with cancer
This study offers an exercise program meant to help people with cancer improve how they live day to day. It may fit you if you are getting treatment now, starting soon, or finished within the last 5 years and can safely do mild activity.
Calgary, AlbertaAges 18–100 - NCT04483804Recruiting
Using computer image features to study breast cancer
This study looks at breast cancer images to see whether computer-extracted patterns (“radiomics”) can help improve understanding of the disease. You may be included if your breast cancer diagnosis is confirmed and your medical records are complete.
Hanzhou, ZhejiangAges 18–80 - NCT04486495Recruiting
Minimally invasive lymph node treatment after chemo for node-positive breast cancer
This study looks at a less invasive way to check and treat lymph nodes in the armpit after you receive chemotherapy (and sometimes immunotherapy) before breast surgery. It may help people with cancer that has already spread to armpit lymph nodes by improving how staging and treatment are done.
's-HertogenboschAges 18 years+ - NCT04501419Recruiting
Mobile ultrasound test to help diagnose breast cancer
This study checks whether a tablet-based ultrasound can find breast lumps that look suspicious for cancer. If it works well, it could help diagnose breast cancer faster in Nigeria where patients may need a biopsy or surgery next.
Ile-IfeAges 18 years+ - NCT04523857RecruitingPhase 2
Abemaciclib and hydroxychloroquine after breast cancer relapse risk
This Phase 2 trial tests whether abemaciclib plus hydroxychloroquine can kill tiny “leftover” cancer cells in the bone marrow after standard breast cancer treatment. It may help lower the chance of cancer coming back by targeting minimal residual disease.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04526587Recruiting
Study of breast cancer markers after CDK4/6 inhibitor treatment
This study looks at lab markers and clinical features in people with certain types of breast cancer who are being treated with, or have already been treated with a CDK4/6 inhibitor like abemaciclib (ciclib-based therapy). It aims to understand patterns that may help doctors better characterize breast cancer after these treatments.
Buffalo, New YorkAges 18 years+ - NCT04529044RecruitingPhase 2
177Lu-DOTATATE for advanced breast cancer with targeted receptors
This Phase 2 trial tests whether 177Lu-DOTATATE can slow or shrink stage IV or recurrent breast cancer. It targets tumor “receptors” found on scans, using a radioactive medicine that delivers radiation directly to cancer cells.
Portland, OregonAges 18–100 - NCT04540692RecruitingPhase 3
Testing chemotherapy timing for certain HER2-negative breast cancers
This Phase 3 trial studies different ways of giving common chemotherapy drugs (anthracyclines and taxanes) for locally advanced breast cancer that is HER2-negative. It aims to see which order or “sequencing” may work better for people like you.
Cachoeiro de Itapemirim, Espírito SantoAges 18 years+ - NCT04543799Recruiting
Sleep quality study in prostate and early breast cancer patients
This trial studies how sleep quality changes while people with prostate cancer or early breast cancer receive standard treatments. It may help doctors understand which treatment factors affect sleep and identify who might benefit from support for sleep problems.
BellinzonaAges 18 years+ - NCT04553770RecruitingPhase 2
Trastuzumab deruxtecan with or without anastrozole for early breast cancer
This Phase 2 study tests whether trastuzumab deruxtecan alone or combined with anastrozole can control early-stage breast cancer that is HER2-low and hormone-receptor positive. It aims to improve outcomes after initial surgical treatment by targeting cancer cells that may have low levels of HER2.
Fullerton, CaliforniaAges 18 years+ - NCT04563507RecruitingPhase 2
Immunotherapy plus hormone therapy for metastatic ER-positive breast cancer
This Phase 2 study tests a combination of immune-based treatments along with hormone (endocrine) therapy to slow or shrink advanced, hormone-receptor positive, HER2-negative breast cancer. You may be a candidate if your cancer has progressed after standard hormone-blocking medicines and you can start treatment with CDK4/6 medicine plus an aromatase inhibitor.
New York, New YorkAges 18–90 - NCT04585750RecruitingPhase 1/Phase 2
Study drug for TP53 Y220C-mutated advanced cancers
This early-phase study tests PC14586 (rezatapopt) in people with advanced or metastatic solid cancers that carry a specific TP53 mutation called Y220C. It mainly looks at safety and how well the treatment may work, sometimes combined with pembrolizumab.
Irvine, CaliforniaAges 12 years+ - NCT04590560Recruiting
Best timing for breast screening in women ages 45–49 and 70–74
This study looks at the best time interval for breast cancer screening (mammograms) for women in two age groups. The goal is to reduce missed cancers while avoiding unnecessary tests.
Meldola (FC), FCAges 45–49 - NCT04603209Recruiting
Check-in registry for radiation during breast-conserving surgery
This registry study tracks people with early-stage, single-area breast cancer to understand outcomes when radiation is given during breast-conserving surgery. It may help doctors improve treatment planning for patients like you.
Santa Monica, CaliforniaAges 18 years+ - NCT04608357Recruiting
Testing digital patient avatars to guide treatment for metastatic breast cancer
This study tests whether a computer “avatar” made from your health information can help choose the best systemic therapy (medications that treat cancer throughout the body) for metastatic breast cancer. You may be asked to provide a tissue sample (biopsy) so the team can build and guide the treatment plan.
Toronto, OntarioAges 18 years+ - NCT04616300Recruiting
Exercise program to support brain function during breast cancer chemo
This trial studies whether a structured exercise program can help protect or improve thinking and memory in people with breast cancer while they are starting chemotherapy after surgery. It may help with “chemo brain” by targeting brain function during treatment.
Toronto, OntarioAges 18–65 - NCT04625023Recruiting
Study of breast cancer biology using mechanics in the body
This trial looks at how breast cancer works in the body, using new “mechanics” measurements to better guide treatment. It may be most helpful if you have (or may have) breast cancer and can take part in study visits and procedures.
Bergamo, BergamoAges 18 years+ - NCT04636710Recruiting
Treatment approach study for stage III inflammatory breast cancer
This study looks at how to best plan local treatments (like surgery and/or radiation) for people with stage III inflammatory breast cancer. It may help doctors refine care plans for this aggressive subtype by studying how patients are treated and what outcomes they have.
Boston, MassachusettsAges 18 years+ - NCT04646759RecruitingPhase 3
Fulvestrant or capecitabine plus pyrotinib for metastatic breast cancer
This Phase 3 trial tests adding pyrotinib to standard hormone-based treatments (fulvestrant or capecitabine) to slow or control metastatic breast cancer. It’s for tumors that are hormone-receptor positive and HER2 positive, where standard options have been used before.
Guangzhou, GuangdongAges 18–80
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Common questions
- Are there clinical trials for breast cancer?
- Yes. Clin2 currently lists 2,470 recruiting breast cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.