Clinical trials
Breast cancer clinical trials
Cancer that forms in the cells of the breast, the most common cancer in women. We’re tracking 2,460 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07483307RecruitingPhase 2
Hormone therapy before surgery for lobular breast cancer
This trial tests whether taking hormone therapy before surgery can improve outcomes for women with a specific type of breast cancer called lobular breast cancer. If you qualify, you would receive endocrine therapy for 6 months before your planned breast-conserving surgery.
Basking Ridge, New JerseyAges 50 years+ - NCT07484087Recruiting
Ablation vs. Surgery for Early Breast Cancer
This trial compares a less invasive treatment called ablation (which uses extreme cold to destroy the tumor) with standard surgery for early-stage breast cancer. It is for women aged 50 or older with a small, low-risk tumor that has not spread.
Beijing, Beijing MunicipalityAges 50 years+ - NCT07486089RecruitingPhase 1/Phase 2
Dual-target CAR-NK cells for advanced breast cancer
This trial tests a new type of immune cell therapy (CAR-NK cells) that targets two markers on breast cancer cells. It is for people with advanced HER2-positive or triple-negative breast cancer who have tried other treatments and need new options.
Shenzhen, GuangdongAges 18–75 - NCT05716893RecruitingPhase 2
Aerobic exercise program for people getting breast cancer treatment
This Phase 2 study tests whether a supervised aerobic (cardio) training program can improve health and exercise capacity for people receiving treatment for primary breast cancer. You may join if you currently do very little moderate-to-vigorous exercise and can safely complete a special treadmill test that measures breathing and heart response.
Basking Ridge, New JerseyAges 18 years+ - NCT05945732Recruiting
Testing T-DXd or chemo for HER2-low or HR-positive breast cancer
This study looks at treatment choices for adults with breast cancer that has spread and cannot be removed by surgery (unresectable metastatic disease). It focuses on people with HER2-low (and some HER2-ultralow) and/or hormone-receptor positive cancer, and compares how well treatments like T-DXd or standard chemotherapy work.
GrazAges 18 years+ - NCT05377996RecruitingPhase 1/Phase 2
Study drug for advanced solid tumors with tumor tissue testing
This early-stage study tests emiltatug leda-dotin (Emi-Le) in people with advanced or recurring solid cancers. It aims to see how the drug works and how safely it can be given, using tumor tissue testing to help understand who may benefit.
Phoenix, ArizonaAges 18 years+ - NCT07492394RecruitingPhase 2
Testing dalpiciclib with or without entinostat and letrozole for early breast cancer
This trial is testing a combination of three drugs (dalpiciclib, entinostat, and letrozole) for women with early-stage, hormone-receptor-positive, HER2-negative breast cancer. It aims to see if adding these medications before surgery can help shrink the tumor.
Shijiazhuang, HebeiAges 18–75 - NCT07498829Recruiting
Cancer risk genetic testing for people with female organs
This study offers free genetic testing to women, trans men, and non-binary people (with female reproductive organs) who have not had previous testing for certain cancer-related genes. It aims to find people at higher risk for cancer so they can take steps to prevent it or catch it early.
LondonAges 18 years+ - NCT07503496Recruiting
Biobran supplement for breast cancer chemo support
This trial tests if a supplement called Biobran (made from rice bran) can help support people with breast cancer who are receiving chemotherapy. It may reduce side effects or improve treatment tolerance.
TaichungAges 20–65 - NCT07503717Recruiting
Brain scan surveillance in HER2-positive metastatic breast cancer
This study tests whether regular brain scans (surveillance) help spot brain metastases early in people with HER2-positive breast cancer that has spread to other parts of the body. Participation involves being randomly assigned to either routine brain scans or no extra scans to see which approach is better.
BeaumontAges 18 years+ - NCT07505797Recruiting
Ultrasound imaging study for suspicious breast lesions
This study is testing a new ultrasound device (ATUSA) to see how well it can image breast lesions that have been classified as suspicious (BI-RADS 4 or 5). If you have a recent finding that needs further evaluation, this research might help improve detection methods.
Sacramento, CaliforniaAges 18–94 - NCT07507890Recruiting
Nipple-sparing mastectomy through one armpit incision
This trial tests a less invasive surgery for early-stage breast cancer that removes breast tissue through a single small cut in the armpit while keeping the nipple. It may be an option for women with small to medium breasts who are candidates for immediate breast reconstruction.
Candiolo, TurinAges 18 years+ - NCT07510698Recruiting
Same-day awake mastectomy with immediate breast reconstruction
This study tests whether people can have a mastectomy while awake (using numbing medicine instead of general anesthesia) and go home the same day with immediate breast reconstruction. It may be an option if you're healthy enough and have support at home.
Rome, RomeAges 18–75 - NCT07510802RecruitingPhase 1/Phase 2
CAR-NK cells for advanced HER2+ or triple-negative breast cancer
This trial tests a new type of immune cell therapy (CAR-NK cells) that targets specific proteins on breast cancer cells. It's for people with advanced HER2-positive or triple-negative breast cancer who have tried other treatments or can't take them.
Shenzhen, GuangdongAges 18–75 - NCT07531836Recruiting
Exercise and wellness program before breast cancer surgery
This trial tests whether a personalized exercise and wellness program before surgery helps older adults with breast cancer recover better and stay stronger. You would work with a team to prepare your body for surgery over several weeks.
Pamplona, NavarreAges 65 years+ - NCT07542496Recruiting
Real-world study of breast cancer treatment with pertuzumab biosimilar
This study observes how a biosimilar version of pertuzumab (a targeted breast cancer drug) works in real-world patients. Researchers will track outcomes in patients receiving this drug either before surgery or as a first treatment for advanced breast cancer.
AlgiersAges 19 years+ - NCT07555210Recruiting
Bone Density Changes During Cancer Immunotherapy
This study tracks how a type of cancer treatment called anti-PD-1 immunotherapy affects bone strength over time. Researchers want to understand whether this treatment causes bone density loss and help develop ways to protect bones during cancer care.
Nashville, TennesseeAges 18 years+ - NCT07557225Recruiting
New PET Scan for Detecting Multiple Cancer Types
This study tests a new type of PET scan (a specialized imaging test) that may better detect certain cancers by looking for a specific marker found on many tumor types. The scan uses a new tracer called 18F-T2 to help doctors see cancer more clearly.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07563595Recruiting
Elacestrant for advanced ER+ HER2- breast cancer with ESR1 mutation
This trial tests elacestrant, a new hormone therapy drug, in women whose advanced or spread breast cancer has stopped responding to first-line hormone treatment. The drug is designed to work against a specific genetic change (ESR1 mutation) that can develop in these cancers.
Freiburg im BreisgauAges 18 years+ - NCT07572370Recruiting
Reducing Follow-up Visits After Breast Cancer Treatment
This study tests whether patients who have finished breast cancer treatment and are doing well can safely have fewer doctor visits and scans. Researchers want to see if reducing routine surveillance affects quality of life and health outcomes.
DublinAges 18 years+ - NCT07574671Recruiting
Ketogenic Diet Study for Early-Stage Breast Cancer
This study tests whether a ketogenic diet (high fat, low carb) can help change the environment around breast cancer tumors in ways that might slow cancer growth. You'll follow the diet for several months while researchers monitor your health and take measurements.
San Antonio, TexasAges 18 years+ - NCT07579286Recruiting
Skipping lymph node surgery in early breast cancer
This trial tests whether older women with early-stage, slow-growing breast cancer can safely skip removal of underarm lymph nodes during surgery. The goal is to reduce surgery-related side effects while maintaining safety.
Saint Petersburg, Russian FederationAges 60 years+ - NCT07582887Recruiting
Genetic Testing to Predict Side Effects from Breast Cancer Antibody Drugs
This study examines how genetic differences affect how your body handles three newer breast cancer medications (Sacituzumab Govitecan, Trastuzumab Deruxtecan, or Datopotamab Deruxtecan). A blood test will check your UGT1A1 gene to help doctors predict which side effects you might experience and adjust your treatment accordingly.
Granada, GranadaAges 18 years+ - NCT07586826RecruitingPhase 2
Romiplostim N01 plus ATRA for low platelets after cancer treatment
This trial tests a combination of two drugs (romiplostim N01 and ATRA) to help raise platelet counts in people whose platelets dropped after chemotherapy for gynecologic, breast, or lung cancer—even though their cancer is now gone. Low platelets can cause bleeding problems, so this treatment aims to help your body make more platelets.
BeijingAges 18 years+
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Common questions
- Are there clinical trials for breast cancer?
- Yes. Clin2 currently lists 2,460 recruiting breast cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.