Clinical trials
Breast cancer clinical trials
Cancer that forms in the cells of the breast, the most common cancer in women. We’re tracking 2,466 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06377852RecruitingPhase 3
Dosing study for older adults with advanced breast cancer
This trial studies how well different doses of CDK4/6 inhibitors (palbociclib or ribociclib) work in people aged 65 or older with HR+/HER2- metastatic breast cancer. It aims to find the best starting dose to balance effectiveness and side effects.
Chandler, ArizonaAges 65 years+ - NCT06400849Recruiting
Cooling and compression to prevent nerve damage from chemo
This trial tests whether adding a cooling and compression treatment to your hands and feet during chemotherapy can help prevent nerve damage (neuropathy) caused by the drug paclitaxel. It may be a good option for people with breast cancer who are about to start this type of chemotherapy and want to reduce side effects.
NiceAges 18–99 - NCT06415032Recruiting
Quilting sutures after mastectomy to improve recovery
This study tests whether using special stitches (quilting sutures) during mastectomy helps reduce fluid buildup or other complications after surgery. It is for people having one breast removed without immediate reconstruction.
LeuvenAges 18 years+ - NCT06426810Recruiting
New vs. standard surgical tool for bleeding control after lymph node biopsy
This trial compares two tools used during surgery to stop bleeding after a sentinel lymph node biopsy for breast cancer. It aims to see if a newer bipolar system is better than the standard electrocautery device.
Seoul, Dongjak-guAges 20–80 - NCT06427226RecruitingPhase 2
Testing dapagliflozin to protect the heart during breast cancer chemo
This trial tests whether a daily pill called dapagliflozin can help protect the heart from damage caused by doxorubicin chemotherapy in people being treated for early-stage breast cancer. If you are starting doxorubicin and have a healthy heart, this might lower your risk of heart problems later.
Alexandria, Bab SharqiAges 18–65 - NCT06429761RecruitingPhase 4
Safety study of Trastuzumab Deruxtecan in Indian patients with breast cancer
This study tests the safety of the drug Trastuzumab Deruxtecan (T-DXd) in Indian patients with a specific type of advanced breast cancer (called HER2-positive) that has spread and cannot be removed by surgery. It is for patients who have already received anti-HER2 treatment.
BangaloreAges 18 years+ - NCT06439771RecruitingPhase 2
Testing YL202 for advanced breast cancer
This trial tests a new drug called YL202 for people with advanced breast cancer. It is for those who have already tried certain targeted treatments (HER2 or TROP2 antibody-drug conjugates) and they stopped working. The goal is to see if YL202 can help shrink tumors or slow cancer growth.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06462092RecruitingPhase 1/Phase 2
Sacituzumab Govitecan and Spinal Chemo for Breast Cancer Spread to Spinal Fluid
This trial tests a combination of a targeted antibody-drug (sacituzumab govitecan) and chemotherapy given into the spinal fluid. It is for people with HER2-negative breast cancer that has spread to the membranes around the brain and spinal cord (leptomeningeal metastases). The goal is to see if this treatment can help control the cancer in the central nervous system.
Huizhou, GuangdongAges 18–75 - NCT07132034Recruiting
Stress reduction through acupuncture for breast cancer survivors
This trial tests whether acupuncture can help reduce stress in people who finished breast cancer treatment in the last 6 months. You must have a distress score of 5 or higher, and you can be using other treatments or therapies.
BaselAges 18 years+ - NCT06489665Recruiting
Testing a clearer mammogram for breast imaging
This study tests a new type of mammogram that might give clearer pictures of breast tissue. It is for women who are either scheduled for breast surgery or getting a regular mammogram.
Zurich, Canton of ZurichAges 18 years+ - NCT06500208RecruitingPhase 2
Adebrelimab plus chemo before surgery for high-risk breast cancer
This trial tests a combination of an immunotherapy drug (adebrelimab) plus chemotherapy before surgery for people with high-risk, hormone receptor-positive, HER2-negative breast cancer. The goal is to see if this approach can shrink tumors more effectively than chemotherapy alone.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06504914Recruiting
A lifestyle program for Black female breast cancer survivors
This study tests a lifestyle program designed for Black women who have survived breast cancer. It aims to help with high blood pressure or weight management by teaching healthy cooking and habits.
Chicago, IllinoisAges 18–99 - NCT06522568Recruiting
Mammogram decision help for women in rural areas
This trial tests a shared decision-making tool to help women aged 39-49 talk with their doctor about whether to get a mammogram. It aims to make the choice clearer for patients in rural settings.
Keene, New HampshireAges 39–49 - NCT06523894Recruiting
Radiation therapy for breast cancer patients over 70
This trial tests a precise type of radiation called SBRT for breast cancer in patients aged 70 or older who cannot have surgery or choose not to. The goal is to see if this treatment can effectively control the tumor without surgery.
GenevaAges 70 years+ - NCT06529614Recruiting
Study of a microRNA detection test in healthy people
This trial tests a new way to detect tiny molecules called microRNAs in the body. It is looking for healthy volunteers to help see how well the detection works.
Wuhan, HubeiAges 18–75 - NCT06533384RecruitingPhase 3
PARP inhibitor or chemo plus immunotherapy after surgery for high-risk TNBC
This trial tests whether adding a PARP inhibitor or capecitabine (chemo) to a PD-1 inhibitor (immunotherapy) after surgery helps prevent triple-negative breast cancer from coming back. It's for people with high-risk disease who have completed initial treatment.
Guangzhou, GuangdongAges 18–70 - NCT06548646Recruiting
Nerve blocks for pain relief after mastectomy
This study compares two types of nerve blocks (thoracic interfascial plane block vs. erector spinae plane block) to see which provides better pain relief after a mastectomy. It may help you have less pain and need fewer painkillers after surgery.
Cairo, AbbasiyaAges 21 years+ - NCT06574022RecruitingPhase 4
Comparing two pain blocks for mastectomy recovery
This trial compares two types of pain blocks (PECS-II and pectoral blocks) to see which works better after mastectomy. The goal is to improve pain control and recovery for patients with breast cancer or high risk.
Cincinnati, OhioAges 18 years+ - NCT07528716RecruitingPhase 3
AI-guided treatment for HER2-positive breast cancer
This trial tests whether an artificial intelligence model can help doctors choose the best targeted therapy before surgery for HER2-positive breast cancer (a type of breast cancer with a protein called HER2). The goal is to improve how well the treatment works and reduce side effects.
ShanghaiAges 18–75 - NCT06608043Recruiting
Reborn: a lifestyle program for breast cancer survivors
This trial tests a lifestyle adjustment program for women who have finished chemotherapy for early-stage breast cancer. It aims to help you make healthy changes and improve your well-being.
IstanbulAges 18 years+ - NCT06627712RecruitingPhase 3
SBRT with immunotherapy and chemo for early-stage triple-negative breast cancer
This trial tests whether combining targeted radiation (SBRT) with immunotherapy (PD-1 inhibitor) and chemotherapy can improve outcomes for people with early-stage triple-negative breast cancer that has not spread far. It aims to find a more effective treatment option.
Sichuan, ChengduAges 18–65 - NCT06643585RecruitingPhase 3
Comparing T-DXd to standard therapy for molecular relapse in early breast cancer
This trial compares a new drug called Trastuzumab-Deruxtecan (T-DXd) to standard treatment for people with early breast cancer whose cancer has come back at a molecular level (detected by a blood test) but hasn't spread to other parts of the body. The goal is to see if T-DXd can prevent the cancer from returning.
UlmAges 18–75 - NCT06645808RecruitingEarly Phase 1
PET imaging study for various solid tumors
This study uses a special PET scan to see if a new imaging agent can help find and monitor certain solid tumors. It is for people with colon, rectal, sarcoma, breast, lung, head and neck, esophageal, stomach, pancreas, bladder cancers, or glioblastoma who have had standard treatment before surgery.
Groningen, Provincie GroningenAges 18 years+ - NCT06648278Recruiting
Support and technology study for breast cancer patients
This trial tests a program called PONTS 2.0 that uses phone texts and online tools to support breast cancer patients through their treatment. It aims to make it easier for patients to get the help they need.
San Francisco, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for breast cancer?
- Yes. Clin2 currently lists 2,466 recruiting breast cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.