Clinical trials
Breast cancer clinical trials
Cancer that forms in the cells of the breast, the most common cancer in women. We’re tracking 2,417 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06855784Recruiting
Time-Restricted Eating for Menopause and Breast Cancer
This study tests if time-restricted eating (eating only during a set window each day) can help women with menopausal symptoms, including those who have had hormone-sensitive breast cancer and are on hormone-blocking therapy.
Geneva, Canton of GenevaAges 45–60 - NCT06823440Recruiting
Preventing nerve damage from chemo with compressive therapy
This trial tests if wearing compressive therapy (like special sleeves or stockings) during weekly paclitaxel chemotherapy can prevent nerve damage (peripheral neuropathy) in breast cancer patients. It is for people who have not yet had nerve issues or diabetes.
BrnoAges 18–70 - NCT06810804RecruitingPhase 2
Study of NBQ72S for breast cancer that has spread to the brain lining
This trial tests a new drug, NBQ72S, for people with breast cancer that has spread to the lining of the brain or spinal cord (leptomeningeal metastasis). It aims to see if the drug is safe and helpful for these patients.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06750484RecruitingPhase 2
Testing trastuzumab deruxtecan in HER2-zero breast cancer
This trial tests a new drug called trastuzumab deruxtecan (a targeted antibody-drug combination) for people with advanced breast cancer that never showed any HER2 protein (HER2-zero). The goal is to see if it can shrink tumors and improve outcomes for those who have already had standard treatments.
New Haven, ConnecticutAges 18 years+ - NCT06735131RecruitingPhase 2
Radiation and immunotherapy for advanced triple-negative breast cancer
This study tests a combination of radiation therapy and immunotherapy for people with advanced triple-negative breast cancer who haven't had chemotherapy for their advanced disease. It aims to see if adding radiation to standard chemotherapy can help shrink tumors and improve outcomes.
Guangzhou, GuangdongAges Any age - NCT06002022Recruiting
How hormone therapy affects your quality of life
This study looks at how hormone therapy affects your quality of life. You'll answer questionnaires about your symptoms and well-being over time.
ValenciaAges 18–75 - NCT06709651Recruiting
Gut bacteria treatment for triple-negative breast cancer
This trial tests whether a treatment that targets your gut bacteria (microbiome) can help fight triple-negative breast cancer before surgery. It is for people with newly diagnosed, untreated triple-negative breast cancer that has not spread far.
Cork, MunsterAges 18 years+ - NCT06706570Recruiting
PIK3CA gene testing for breast cancer
This trial tests for a specific gene change (PIK3CA mutation) in your breast cancer cells. The results will help doctors decide if a targeted treatment is right for you. It's for people with hormone-receptor-positive, HER2-negative breast cancer that has spread and not yet been treated in that setting.
Milan, MIAges 18 years+ - NCT05704166RecruitingPhase 2
Pirfenidone to prevent lung injury after breast radiation
This trial tests whether pirfenidone, a medication, can prevent acute lung injury caused by radiation therapy in people with breast cancer. You may be randomly assigned to pirfenidone or a placebo (inactive pill) to see which better protects the lungs during and after radiation.
Fuzhou, FujianAges 18–75 - NCT06700070RecruitingEarly Phase 1
Testing a microdose drug in solid tumors before surgery
This study tests a tiny amount of an experimental drug (PBA-0111) injected directly into tumors that will be surgically removed later. The goal is to see how the drug affects the tumor tissue, which may help guide future treatments for solid tumors like head and neck cancer, certain sarcomas, or triple-negative breast cancer.
Shreveport, LouisianaAges 18 years+ - NCT06704945RecruitingPhase 3
Skipping armpit surgery after good chemo response
This trial tests whether it's safe to skip armpit surgery in people whose breast cancer has responded well to chemotherapy and whose lymph nodes appear cancer-free on ultrasound. It aims to reduce side effects like arm swelling while still controlling the cancer.
SeoulAges 19 years+ - NCT06371274Recruiting
Oral vitamin A drug plus immunotherapy for advanced triple-negative breast cancer
This trial tests a combination of an oral vitamin A-based drug (all-trans retinoic acid) and an immunotherapy (toripalimab) for people with advanced triple-negative breast cancer that hasn't responded to at least two prior treatments. The goal is to see if this combination can shrink or control the cancer.
Hangzhou, Zhejiang Province, P.R. ChinaAges 18 years+ - NCT06682195RecruitingPhase 2
Chemo plus toripalimab before surgery for TNBC
This trial tests whether giving chemotherapy plus the immunotherapy drug toripalimab before surgery can improve outcomes for women with early-stage triple-negative breast cancer that tests positive for PD-L1.
Nanchang, JiangxiAges 18–70 - NCT06657222RecruitingPhase 1/Phase 2
Study of TUB-030 for advanced solid tumors
This trial tests a new drug called TUB-030 in people with advanced solid tumors that have not responded to other treatments. The goal is to see if it is safe and effective.
New Haven, ConnecticutAges 18 years+ - NCT06666439Recruiting
Tracking lobular breast cancer with a blood test
This study is testing a new blood test that looks for cancer DNA to track how lobular breast cancer responds to treatment. It is for people whose cancer has spread and who have not yet started treatment for the spread.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06659146Recruiting
Heat therapy with standard palliative radiation for cancer
This trial tests whether adding heat therapy (using a special lamp) to standard palliative radiation can help treat superficial tumors or lymph nodes that cannot be cured. It aims to improve symptom relief or tumor control for people with advanced cancer.
LondonAges 18 years+ - NCT06645808RecruitingEarly Phase 1
PET imaging study for various solid tumors
This study uses a special PET scan to see if a new imaging agent can help find and monitor certain solid tumors. It is for people with colon, rectal, sarcoma, breast, lung, head and neck, esophageal, stomach, pancreas, bladder cancers, or glioblastoma who have had standard treatment before surgery.
Groningen, Provincie GroningenAges 18 years+ - NCT06648278Recruiting
Support and technology study for breast cancer patients
This trial tests a program called PONTS 2.0 that uses phone texts and online tools to support breast cancer patients through their treatment. It aims to make it easier for patients to get the help they need.
San Francisco, CaliforniaAges 18 years+ - NCT06652295Enrolling by invitation
Self-physiotherapy for lymphedema
This trial tests whether a self-guided physiotherapy program can help manage lymphedema (arm swelling) after breast cancer treatment. If you have had breast cancer-related lymphedema for a while and haven't had recent treatment for it, this study may offer a way to take control of your symptoms.
IzmirAges 18–65 - NCT03053193Recruiting
Testing gene activity to guide breast cancer treatment
This study links breast tumor test results from MammaPrint and optional BluePrint (and full genetic data) with real-world clinical information to understand which new gene activity patterns matter. It may help future patients by improving how doctors use these tests to guide care.
Birmingham, AlabamaAges 18 years+ - NCT06627712RecruitingPhase 3
SBRT with immunotherapy and chemo for early-stage triple-negative breast cancer
This trial tests whether combining targeted radiation (SBRT) with immunotherapy (PD-1 inhibitor) and chemotherapy can improve outcomes for people with early-stage triple-negative breast cancer that has not spread far. It aims to find a more effective treatment option.
Sichuan, ChengduAges 18–65 - NCT06574022RecruitingPhase 4
Comparing two pain blocks for mastectomy recovery
This trial compares two types of pain blocks (PECS-II and pectoral blocks) to see which works better after mastectomy. The goal is to improve pain control and recovery for patients with breast cancer or high risk.
Cincinnati, OhioAges 18 years+ - NCT06552091Recruiting
Digital self-hypnosis for hot flashes from hormone therapy
This trial tests a guided digital self-hypnosis program to help reduce hot flashes caused by hormone therapy for breast cancer. It aims to see if it can make hot flashes less frequent and bothersome.
Vandœuvre-lès-NancyAges 18 years+ - NCT06529614Recruiting
Study of a microRNA detection test in healthy people
This trial tests a new way to detect tiny molecules called microRNAs in the body. It is looking for healthy volunteers to help see how well the detection works.
Wuhan, HubeiAges 18–75
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Common questions
- Are there clinical trials for breast cancer?
- Yes. Clin2 currently lists 2,417 recruiting breast cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.