Clinical trials
Breast clinical trials
Below are recruiting breast clinical trials, each written for real people, not researchers. We’re tracking 2,689 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06037421Recruiting
Bacteria in breast milk of NICU mothers
This study looks at the bacteria naturally found in breast milk. Researchers want to learn more about the germs in milk from mothers whose babies are in the neonatal intensive care unit.
Corbeil-Essonnes, FranceAges 1 hour+ - NCT06026657RecruitingPhase 1/Phase 2
NK cells with or without naxitamab for GD2-positive breast cancer
This trial tests a new treatment using immune cells called NK cells combined with chemotherapy (gemcitabine) and possibly naxitamab for people with a certain type of advanced breast cancer that has spread. It aims to see if this approach can help when standard treatments have stopped working.
Columbus, OhioAges 18 years+ - NCT05345821Recruiting
Study of side effects and satisfaction after silicone breast implants
This trial follows women who get their first breast implant surgery or a repeat (primary vs secondary) and records side effects and how satisfied they feel. It aims to better understand safety and satisfaction with smooth-surface silicone implants.
Santo André, São PauloAges 18 years+ - NCT05586256Recruiting
Shorter radiation for early breast cancer after breast surgery
This trial studies giving whole-breast radiation in a shorter, more concentrated way after breast-conserving surgery. It aims to see if this “ultra-short” schedule is effective and safe for people with early breast cancer.
PerugiaAges 18–99 - NCT05585710Recruiting
Study pulsed rinse during breast implant reconstruction
This trial tests whether a special “pulsed rinse” technique during implant-based breast reconstruction improves care during surgery. If you’re having immediate expander placement at the time of mastectomy, you may be eligible to try this approach under research oversight.
Birmingham, AlabamaAges 18–75 - NCT05116449Recruiting
Supportive care program for women having breast cancer surgery
This trial looks at whether getting supportive oncology care around the time of breast cancer surgery improves quality of life. You would answer questionnaires in French so the team can measure any changes over time.
Guilherand-GrangesAges 18 years+ - NCT04985266RecruitingPhase 2
Watch blood DNA for early breast cancer return, then add palbociclib
This study checks for early signs that ER-positive, HER2-negative breast cancer may be coming back by testing your blood for cancer DNA. If signs are found, it tests whether adding palbociclib plus fulvestrant works better than standard hormone therapy alone to prevent recurrence.
AngersAges 18 years+ - NCT04749446Recruiting
Study of outcomes in breast sarcoma patients
This study looks at the medical details and outcomes of people with breast sarcoma. It may help doctors better understand what treatments and factors are linked to different results over time.
Bologna, BOAges 19 years+ - NCT05003635Recruiting
Testing a vacuum device to improve breast fat reconstruction
This trial tests whether an external vacuum device (EVEBRA) can help surgeons place fat grafts more effectively during breast reconstruction. You may be able to try the device in an office visit and, if you qualify, receive reconstruction using only your own fat.
Maastricht, LimburgAges 23–69 - NCT05914831RecruitingPhase 2
Whole-breast vs partial-breast radiation after breast surgery
This Phase 2 study compares two types of radiation after breast-conserving surgery: treating the whole breast versus treating only part of the breast. It may help find which approach works well while aiming to reduce side effects.
Novi Sad, VojvodinaAges 50 years+ - NCT04661501Recruiting
Trial of special breast skin graft in implant reconstruction
This trial studies whether a lab-made skin graft (called ADM) used with tissue expanders can improve breast reconstruction after mastectomy. It may help people who are planning a specific two-step implant reconstruction approach.
Vancouver, British ColumbiaAges 21–65 - NCT06065748RecruitingPhase 3
New hormone therapy for advanced breast cancer after prior treatment
This trial tests a new oral hormone therapy, giredestrant, against a standard hormone therapy (fulvestrant) when both are given with a CDK4/6 inhibitor. It is for people with advanced ER-positive, HER2-negative breast cancer that has come back after initial hormone therapy, and who have not yet had other treatments for advanced disease.
Daphne, AlabamaAges 18 years+ - NCT06470347RecruitingPhase 1/Phase 2
Testing Pyrrolitinib After Trastuzumab for HER2+ Breast Cancer
This study tests if taking pyrrolitinib (a targeted medicine) can further reduce the risk of breast cancer returning in patients with HER2-positive early breast cancer who have already received trastuzumab after surgery.
Zunyi, GuizhouAges 18–75 - NCT03390894Recruiting
Long-term follow-up of early breast cancer study participants
This study follows people who previously took part in GEICAM early breast cancer trials to learn about long-term outcomes. It may help doctors understand what happens over time and improve future care.
Pamplona, NavarreAges 18 years+ - NCT05305924RecruitingPhase 2
Fulvestrant plus abemaciclib for ER+, HER2− advanced breast cancer
This Phase 2 study tests whether adding abemaciclib to fulvestrant can slow or shrink ER-positive, HER2-negative metastatic breast cancer. It is mainly for people whose cancer has progressed despite prior treatment with a CDK4/6 inhibitor and an aromatase inhibitor.
Houston, TexasAges 18 years+ - NCT06723990Recruiting
HER2 breast cancer treatment decision study
This study tests a tool called HER2DX to help doctors choose the best treatment for early stage HER2 positive breast cancer. It may help tailor therapy before or after surgery.
Milan, ItalyAges 18 years+ - NCT07562321Recruiting
AI-Assisted Learning for Breast Self-Examination Training
This study tests a new way to teach nursing students about breast self-examination using artificial intelligence and flipped learning (where you study materials at home, then practice in class). The goal is to see if this method helps students learn better and feel more confident performing breast exams.
Ankara, AnkaraAges Any age - NCT07497386RecruitingPhase 2
Trastuzumab rezetecan for advanced breast cancer
This trial tests a new drug, trastuzumab rezetecan, for women with breast cancer that has come back or spread and cannot be removed by surgery. It's for those who haven't had chemotherapy for advanced disease but have tried hormone therapy and it stopped working.
Beijing, Beijing MunicipalityAges 18–75 - NCT06762977Recruiting
Study on her2-positive early-stage breast cancer treatment
This study looks at how well a new test can help manage her2-positive early-stage breast cancer. It includes patients who have had treatment before or after surgery with trastuzumab and possibly pertuzumab.
BrindisiAges 18 years+ - NCT05467891RecruitingPhase 2
Ribociclib plus hormone therapy for recurrent breast cancer
This trial tests whether adding ribociclib (a targeted pill) to hormone therapy can control breast cancer that has come back in the breast area or nearby lymph nodes/chest wall. It targets hormone-receptor–positive and HER2-negative tumors to help slow disease after local treatment.
Birmingham, AlabamaAges 18 years+ - NCT07506876RecruitingPhase 2
Combined hormone and chemo before surgery for HER2+ breast cancer
This trial tests combining hormone therapy with chemotherapy and targeted therapy before surgery for a type of breast cancer that is both hormone-receptor-positive (HR+) and HER2-positive. The goal is to see if this combination works better than standard treatment.
Gresham, OregonAges 18 years+ - NCT07132749Enrolling by invitation
NEPA for nausea prevention during T-DXd in advanced HER2+ or HER2-low breast cancer
This trial tests whether the anti-nausea combination NEPA (netupitant and palonosetron) can prevent nausea and vomiting caused by the targeted therapy T-DXd in people with advanced HER2-positive or HER2-low breast cancer. It may help you if you are about to start T-DXd for the first time and want to manage treatment side effects.
Seoul, Gangnam-guAges 19 years+ - NCT07419971Enrolling by invitation
Factors behind breast implant hardening after reconstruction
This study looks at why some women develop hard scar tissue around breast implants after cancer surgery. It aims to find the causes and ways to prevent it.
Chengdu, SichuanAges 18–80 - NCT05730608Recruiting
PET/CT scan test for high-risk breast cancer
This trial studies how an FDG PET/CT scan (a special imaging test that looks for active cancer activity) can be used in people with high-risk primary or recurring breast cancer. It may help doctors better identify areas of concern and guide future care.
DrammenAges 18 years+
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Common questions
- Are there clinical trials for breast?
- Yes. Clin2 currently lists 2,689 recruiting breast studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.