Clinical trials
Breast clinical trials
Below are recruiting breast clinical trials, each written for real people, not researchers. We’re tracking 2,627 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04665882Recruiting
Prediction tool for arm swelling after breast cancer surgery
This trial tests a prediction tool (a “nomogram”) to estimate who is at risk of developing breast cancer–related lymphedema, or long-term arm swelling, after surgery. If you fit the surgery and lymph node criteria, your information may help personalize follow-up and prevention.
Wuhan, HubeiAges 18–80 - NCT04960839Recruiting
Preventive radiation to the other breast after breast cancer surgery
This study looks at whether “preventive” radiation to your other (opposite) breast can lower the chance of future breast cancer in people at higher genetic risk. You must have had surgery for early-stage breast cancer and agree to avoid removing the other breast and ovaries.
Jiangxi, JiangxiAges 30–70 - NCT04261829Recruiting
Full method for breast reconstruction after mastectomy
This trial tests a “full breast reconstruction” approach for people who are planning or have had a breast removal (mastectomy). It may help improve how reconstruction is done and whether you can use the external expansion device as part of the process.
Maastricht, LimburgAges 18 years+ - NCT04993014RecruitingPhase 2
De-escalating treatment after HER2-positive breast cancer responds
This study looks at whether some people with HER2-positive breast cancer can safely receive less (de-escalated) treatment after they finish chemotherapy plus HER2-targeted drugs before surgery. It specifically focuses on people whose cancer shows a complete response on the surgery pathology report.
São PauloAges 18 years+ - NCT05346510Recruiting
Prone CT and ultrasound to check underarm lymph nodes
This study checks how well CT scans and ultrasound (done while lying face-down) can identify underarm lymph node involvement in people with breast cancer before surgery. If accurate, this may help guide whether additional lymph node surgery is needed.
Shenyang, LiaoningAges 18–70 - NCT05427071Recruiting
Tracking a breast cancer marker to guide lymph node surgery
This study tests a special “marker” technique to help surgeons find affected lymph nodes in the armpit after chemotherapy. It may support more targeted surgery and help avoid unnecessary removal of healthy lymph nodes.
Hong KongAges 18 years+ - NCT05003635Recruiting
Testing a vacuum device to improve breast fat reconstruction
This trial tests whether an external vacuum device (EVEBRA) can help surgeons place fat grafts more effectively during breast reconstruction. You may be able to try the device in an office visit and, if you qualify, receive reconstruction using only your own fat.
Maastricht, LimburgAges 23–69 - NCT05603078Recruiting
Breast cancer surgery with a tumor-bed boost and standard radiation
This study looks at whether adding extra targeted radiation to the tumor area before breast-conserving surgery, then using modern breast surgery techniques and whole-breast radiation afterward, improves outcomes for early-stage breast cancer. You may be offered a treatment plan designed to better treat the area where the tumor was removed.
Beijing, Beijing MunicipalityAges Up to 55 years - NCT03150576RecruitingPhase 2/Phase 3
Before-surgery treatment for triple-negative or BRCA breast cancer
This trial tests an “at-the-source” medicine given before surgery to shrink triple-negative and/or BRCA-related breast cancer. It may help doctors see whether it improves tumor response and reduces cancer spread at surgery time.
Cambridge, CambridgeshireAges 16–70 - NCT05665920Recruiting
Shorter radiation after breast surgery for certain node-positive cancer
This trial compares a shorter, more concentrated radiation schedule versus a standard shorter schedule after breast-conserving surgery. It looks at whether the treatment works well and is safe, especially for women whose lymph nodes also need radiation.
São Paulo, São PauloAges 18 years+ - NCT05462457Recruiting
Tests adding a targeted approach for breast cancer with many involved nodes
This trial studies a treatment plan for early breast cancer that involves at least three suspicious lymph nodes on the ultrasound/imaging. It looks at whether a targeted technique—done before surgery with chemotherapy—can improve or guide care when surgery will remove the lymph nodes.
EssenAges 18 years+ - NCT03436069Recruiting
Finding new markers to predict breast cancer outlook
This study looks for new lab “markers” that may help predict how breast cancer is likely to behave over time. Your tumor or health information may be used to find factors that can guide doctors’ predictions.
GrenobleAges 18 years+ - NCT04690439Recruiting
Light therapy to treat breast cancer–related arm swelling
This trial studies whether a noninvasive light-based treatment (photobiomodulation) can reduce breast cancer–related lymphedema, which is swelling in the arm or chest area due to lymph fluid buildup. If you qualify, you’ll be asked to follow a set treatment and follow-up schedule to see if symptoms improve safely.
Hasselt, LimburgAges 18 years+ - NCT05732051RecruitingPhase 2
Nicotinamide riboside to protect the heart during breast cancer chemo
This trial tests whether nicotinamide riboside can help prevent heart problems caused by a common breast-cancer chemotherapy (anthracyclines). If you’re eligible, you’ll be followed to see how your heart is doing during treatment.
Lørenskog, AkershusAges 18 years+ - NCT05430399RecruitingPhase 3
Utidelone vs docetaxel for HER2-negative breast cancer
This trial compares utidelone with docetaxel in people with HER2-negative advanced or metastatic breast cancer. It aims to see which treatment works better and is safer for controlling the cancer and helping patients live longer.
Guangzhou, GangdongAges 18 years+ - NCT05976412Recruiting
Radiation to lymph nodes after surgery for higher-risk breast cancer
This trial looks at whether adding targeted radiation to lymph nodes after breast surgery can lower the chance of breast cancer coming back in people with higher-risk, node-negative disease. If you qualify, you may get a planned radiation approach designed for prevention, not treatment of spread.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06035016Recruiting
Pyrotinib and capecitabine after surgery for HER2+ breast cancer
This study tests whether taking pyrotinib (a daily pill) with capecitabine (another pill) after breast cancer surgery can help prevent HER2-positive early-stage breast cancer from coming back. It is for women who have already had their cancer removed and meet certain risk criteria.
Beijing, Beijing MunicipalityAges 18–75 - NCT06144346Recruiting
Radiation for limited breast cancer spread
This trial tests whether treating each spot of cancer that has spread (but only a few spots) with focused radiation can help control breast cancer. It aims to see if this approach can stop the cancer from growing further without needing strong whole-body treatments right away.
CairoAges 18–70 - NCT04428528Recruiting
Ultrasound-like pictures that track breast tumors during chemotherapy
This study uses a special light-based imaging scan to learn more about breast masses and how tumors may respond to chemotherapy before surgery. The scan is meant to help doctors better characterize tumors and potentially track treatment response.
Toronto, OntarioAges Any age - NCT05888571Recruiting
Testing pre-chest breast reconstruction with or without mesh
This study looks at whether adding mesh (a supportive material) improves results in breast reconstruction placed in front of the chest. It may help some people heal better and get a more comfortable shape, but it depends on your surgery plan and health factors.
Tianjin, Tianjin MunicipalityAges 18–65 - NCT05949541RecruitingPhase 2
Everolimus with first-line hormone therapy for specific breast cancer
This Phase 2 trial tests whether adding everolimus to standard first-line hormone (endocrine) therapy can better control a certain type of advanced breast cancer. It is designed for people whose tumor matches a specific “SNF1 subtype.”
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06259513Recruiting
Skipping armpit surgery for breast cancer patients
This trial tests whether it's safe to skip armpit surgery in older women with small, low-risk breast cancers. If you qualify, you would have a mastectomy without removing lymph nodes from your armpit.
SingaporeAges 21–80 - NCT06268652RecruitingPhase 3
Personalized treatment guided by lab-grown tumor samples for advanced breast cancer
This trial tests whether using a personalized approach—growing your tumor cells in the lab to find the best treatment—can work better than standard treatments chosen by your doctor. It is for people with advanced breast cancer that has stopped responding to at least two previous treatments.
Guangzhou, None SelectedAges 18 years+ - NCT06266026Recruiting
AI-enhanced thermal imaging for breast cancer screening
This study tests a new, non-contact thermal camera (thermography) combined with artificial intelligence to find breast cancer. It is designed for women coming for routine screening, high-risk screening, or diagnostic exams, and aims to see if this painless, radiation-free method can help detect cancer earlier.
HeidelbergAges 18 years+
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Common questions
- Are there clinical trials for breast?
- Yes. Clin2 currently lists 2,627 recruiting breast studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.