Clinical trials
Breast clinical trials
Below are recruiting breast clinical trials, each written for real people, not researchers. We’re tracking 2,689 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06738654Recruiting
Robotic breast-conserving surgery through the armpit for early-stage breast cancer
This trial tests a new robotic technique for removing early-stage breast cancer through the armpit, leaving no scar on the chest. It may be an option for women who want to keep their breast shape and avoid visible scarring.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT04495244Recruiting
Identifying breast cancer through a blood test
This study tests a blood test designed to help find breast cancer. It may help detect the disease earlier, which could make treatment more effective.
Calgary, AlbertaAges 30–75 - NCT06888388Recruiting
Safety of nipple-sparing mastectomy for women with high-risk genes
This study looks at the long-term safety of a type of breast surgery (nipple-sparing mastectomy) in women who carry certain inherited gene changes (BRCA1, BRCA2, PALB2, TP53, CDH1, or PTEN) that increase their risk of breast cancer. The goal is to understand how safe this surgery is over time for these women.
New Haven, ConnecticutAges 18–90 - NCT07544056RecruitingPhase 2/Phase 3
BEBT-209 Plus Chemotherapy for Triple-Negative Breast Cancer
This study tests a new drug called BEBT-209 combined with chemotherapy (carboplatin and gemcitabine) in women with advanced triple-negative breast cancer that has spread or cannot be surgically removed. The goal is to see if this combination can slow or stop cancer growth better than standard treatments.
Guangzhou, GuangdongAges 18–75 - NCT07541079RecruitingPhase 3
Testing a New Breast Cancer Drug for Women Who Can't Tolerate Current Therapy
This study tests giredestrant, a new hormone-blocking medication, in postmenopausal women with early-stage ER+ breast cancer who have experienced intolerable side effects from their current aromatase inhibitor therapy. The trial will measure how well you tolerate this new drug and how it affects your quality of life.
Fountain Valley, CaliforniaAges 18 years+ - NCT07047872Recruiting
3D-printed breast form study for women after mastectomy
This study tests a custom 3D-printed external breast form for people who had a mastectomy without reconstruction. It aims to see if it improves comfort and satisfaction.
Rochester, MinnesotaAges 18 years+ - NCT06518057RecruitingPhase 2
Sparing memory during brain radiation for leptomeningeal metastases
This trial tests a special type of radiation that avoids the memory center of the brain (the hippocampus) while treating cancer that has spread to the lining of the brain and spinal cord. It may help reduce side effects on thinking and memory for people with breast or lung cancer.
San Francisco, CaliforniaAges 18 years+ - NCT06222788Recruiting
Plasma treatment during breast cancer lumpectomy
This trial tests a plasma treatment applied directly to the tumor site during a lumpectomy. It may help improve healing and reduce recurrence for people with early-stage breast cancer.
Montreal, QuebecAges 18 years+ - NCT07543536RecruitingPhase 3
Megestrol Acetate for Fatigue in HER2+ Breast Cancer
This study tests whether a medication called megestrol acetate can help reduce severe tiredness and fatigue in people with advanced breast cancer who are receiving a targeted therapy called T-DXd (trastuzumab deruxtecan). Fatigue is a common side effect that can really impact quality of life.
Guangzhou, GuangdongAges 18–75 - NCT07214532Recruiting
Using a blood test to guide breast cancer therapy
This study tests whether a blood test can help decide when to start additional hormone-blocking therapy for early-stage breast cancer. It aims to see if starting therapy only when the test detects cancer DNA is as effective as giving it to everyone.
Phoenix, ArizonaAges 18 years+ - NCT04768426RecruitingPhase 2
Watching DNA in blood while taking capecitabine after breast cancer
This trial checks how a blood test that looks for cancer DNA (ctDNA) changes during and after you take capecitabine after early triple-negative breast cancer. It aims to see whether these blood test results can help monitor the chance of the cancer coming back.
Stanford, CaliforniaAges 18 years+ - NCT05072314RecruitingPhase 3
Lidocaine drip after breast surgery to improve long-term pain
This Phase 3 study tests whether a long-running lidocaine (a numbing medicine) drip given around the time of breast surgery can improve long-term post-surgery pain and recovery. It may help people who have pain after mastectomy or breast-conserving surgery.
Kingswood, New South WalesAges 18 years+ - NCT07752238Recruiting
Predicting outcomes for newly diagnosed metastatic breast cancer
This study uses information from women with newly diagnosed breast cancer that has spread (metastatic) to create a tool that helps predict how the disease may progress. By looking at your medical records, they hope to improve care and help future patients.
Szombathely, Vas CountyAges 18 years+ - NCT05573893Recruiting
Real-world study of trastuzumab deruxtecan for HER2 breast cancer
This study looks at how people feel (patient-reported outcomes) and their real-world health data while they receive trastuzumab deruxtecan for advanced HER2-positive, HER2-low, or HER2-ultralow breast cancer. It helps researchers understand what outcomes happen outside of tightly controlled clinical trials.
AmbergAges 18–130 - NCT07602907RecruitingPhase 2
Low-dose paclitaxel with immunotherapy for advanced HER2-negative breast cancer
This trial tests a combination of low-dose oral paclitaxel (a chemotherapy pill taken regularly) plus immunotherapy to treat advanced breast cancer that doesn't have high levels of HER2 protein. The goal is to slow or shrink tumors while managing side effects better than traditional high-dose chemotherapy.
Hangzhou, ZhejiangAges 18 years+ - NCT07347600Recruiting
Studying inavolisib for a type of advanced breast cancer
This study tests a targeted therapy called inavolisib for people whose breast cancer has spread (advanced or metastatic), is hormone receptor-positive and HER2-negative, has a PIK3CA mutation, and has stopped responding to hormone therapy. It aims to see if inavolisib is safe and works well for them.
Xiamen, FujianAges 18 years+ - NCT05893966Recruiting
Tested extra radiation to the tumor area in HER2-positive breast cancer
This study follows people with HER2-positive invasive breast cancer to see how adding radiation to the tumor bed may affect outcomes. It may be most relevant if you are scheduled for breast radiation and have not had radiation to the same side before.
Seoul, SeoulAges 19 years+ - NCT06458764Recruiting
Checking sexual health in younger breast cancer survivors on hormone therapy
This study is checking how hormone therapy affects sexual health in younger women who had early-stage breast cancer. You'll fill out questionnaires about your sexual function and well-being.
Torino, TOAges 18–55 - NCT05888571Recruiting
Testing pre-chest breast reconstruction with or without mesh
This study looks at whether adding mesh (a supportive material) improves results in breast reconstruction placed in front of the chest. It may help some people heal better and get a more comfortable shape, but it depends on your surgery plan and health factors.
Tianjin, Tianjin MunicipalityAges 18–65 - NCT03723928Recruiting
Blood test–guided monitoring for metastatic breast cancer treatment
This study checks whether specific blood “tumor marker” levels can help monitor how hormone receptor–positive, HER2-negative metastatic breast cancer responds to first-line therapy. It uses regular blood tests (and sometimes scans) to see if this marker-based monitoring is useful and reliable.
Anchorage, AlaskaAges 18 years+ - NCT07613151Recruiting
Lobular breast cancer with low hormone receptors
This study looks at a rare type of breast cancer called invasive lobular carcinoma that has low or no hormone receptors. The goal is to learn more about how this cancer behaves, which may help improve future treatments.
PadovaAges 18 years+ - NCT06716073Recruiting
Endoscopic vs standard breast-conserving surgery after chemo
This study compares two types of breast-conserving surgery for women who have already had chemotherapy before their operation. It aims to see if using a tiny camera (endoscope) leads to equally good long-term results as standard breast-conserving surgery.
Guangzhou, GuangdongAges 18–75 - NCT06450873RecruitingPhase 2
Turkey tail mushroom before breast cancer surgery
This trial tests whether taking a turkey tail mushroom supplement before breast cancer surgery can help the immune system fight the cancer. It is for post-menopausal women with a common type of breast cancer (ER-positive, HER2-negative) that is growing at a moderate or faster rate (Ki-67 score of 10% or more).
Scottsdale, ArizonaAges 18 years+ - NCT06217185RecruitingPhase 4
Pyrotinib and trastuzumab with chemo for HER2+ advanced breast cancer
This trial tests a combination of two targeted medicines (pyrotinib and trastuzumab) with chemotherapy to treat HER2-positive advanced breast cancer that has returned or spread after stopping trastuzumab.
Shijiazhuang, HebeiAges 18–70
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Common questions
- Are there clinical trials for breast?
- Yes. Clin2 currently lists 2,689 recruiting breast studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.