Clinical trials
Bupivacaine clinical trials
Below are recruiting bupivacaine clinical trials, each written for real people, not researchers. We’re tracking 198 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07033104Recruiting
Adding calcitonin to numbing medicine for C-section pain relief
This study tests if adding a medication called calcitonin to the usual numbing medicine (bupivacaine) can provide better pain relief after a cesarean section. It is for women who are having a planned C-section under spinal anesthesia.
Tanta, Gharbia GovernorateAges Any age - NCT06989866Enrolling by invitationPhase 3
Testing if numbing injections reduce pain pill use after nose surgery
This trial tests whether a numbing injection (regional anesthesia) during nose surgery can reduce the need for strong pain pills afterward. It's for people having their first nose surgery at specific military hospitals.
Portsmouth, VirginiaAges 18 years+ - NCT06878014RecruitingPhase 4
Morphine for pain relief after hip replacement surgery
This trial tests different doses of morphine given during spinal anesthesia to find the safest and most effective way to control pain after hip replacement surgery. If you are having a total hip replacement, you may be able to join.
Sosnowiec, Silesian VoivodeshipAges 18–75 - NCT06809998RecruitingPhase 1/Phase 2
Steroid injection in non-surgical knee before knee replacement
This study tests whether a single steroid injection in the healthy knee (the one not being replaced) can reduce pain and improve recovery after total knee replacement. It may help people who have arthritis in both knees but are only having one replaced now.
Toronto, OntarioAges 18 years+ - NCT05233462Recruiting
Compare two spinal anesthesia bupivacaine dose methods for C-sections
This trial looks at whether adjusting the dose of bupivacaine by height works better than using a standard dose for spinal anesthesia during planned C-sections. It may help improve safety and comfort by aiming for the right level of numbing effect.
CaenAges 18–45 - NCT06734975RecruitingPhase 2
Nerve block for better recovery after vocal cord surgery
This study tests if a nerve block can help reduce pain and improve recovery after surgery to remove a noncancerous growth on the vocal cords. Participants will be randomly assigned to receive either the nerve block or standard care.
Newark, New JerseyAges 18 years+ - NCT06714279RecruitingPhase 1
Pain relief methods for gallbladder surgery
This trial compares two ways to reduce pain after laparoscopic gallbladder removal: one uses a nerve block during surgery and the other uses local anesthetic inside the abdomen. The goal is to find which approach provides better pain relief.
DublinAges 18 years+ - NCT06639503RecruitingPhase 1
Nerve block for leg fracture surgery recovery
This trial tests if a nerve block given during surgery for a broken tibia (shin bone) can reduce pain after the operation. It may help you need fewer painkillers and recover more comfortably.
Chicago, IllinoisAges 18 years+ - NCT06574022RecruitingPhase 4
Comparing two pain blocks for mastectomy recovery
This trial compares two types of pain blocks (PECS-II and pectoral blocks) to see which works better after mastectomy. The goal is to improve pain control and recovery for patients with breast cancer or high risk.
Cincinnati, OhioAges 18 years+ - NCT05996133RecruitingPhase 4
Neck Numbing Shot vs. Sham for Neck Surgery Pain
This trial tests whether a numbing injection (called a multifidus cervicis plane block) in the neck muscles helps reduce pain after back-of-the-neck fusion surgery. Half the participants will get the real block, the other half a sham (fake) block, to see if it really works.
Hartford, ConnecticutAges 40–80 - NCT06452147Recruiting
Anesthesia types for preventing confusion after hip surgery in older adults
This study looks at different ways to give anesthesia during hip surgery to help older patients think and remember better afterward. It may help prevent confusion or memory problems that sometimes happen after surgery.
Dongyang, ZhejiangAges 65 years+ - NCT04979338RecruitingPhase 3
Opioid-sparing pain control for gender-affirming surgery
This Phase 3 study tests ways to manage pain during and after gender-affirming surgery while using less opioid medicine. It may help improve comfort after surgery and reduce opioid-related side effects.
Los Angeles, CaliforniaAges 18 years+ - NCT06350981Enrolling by invitationPhase 2/Phase 3
Pain control after lower back fusion surgery
This study is comparing different ways to manage pain after a specific type of lower back fusion surgery called TLIF. The goal is to find the best pain control plan to make recovery more comfortable.
Tampa, FloridaAges 18 years+ - NCT06353529RecruitingPhase 4
Pain management after pituitary tumor surgery
This study tests a nerve block (called sphenopalatine ganglion block) for pain relief after pituitary tumor surgery through the nose. It aims to see if this block helps manage pain and reduces the need for other pain medicines.
Hamilton, OntarioAges 18–100 - NCT06349668RecruitingPhase 3
Comparing spinal morphine and IV lidocaine for robotic kidney surgery
This trial compares two ways to manage pain during robotic-assisted kidney or ureter surgery: a spinal injection of morphine or an intravenous infusion of lidocaine. The goal is to see which method provides better pain relief and recovery.
KalmarAges 18 years+ - NCT06271707RecruitingPhase 4
Nerve block for surgery pain relief
This trial tests a nerve block (stellate ganglion block) to see if it helps reduce pain after surgery to remove part or all of the lung or esophagus. It may be an option for adults aged 18-85 having these procedures.
Minneapolis, MinnesotaAges 18–85 - NCT06271265RecruitingPhase 1
Testing EXPAREL for pain after heart surgery in children
This study tests a long-acting pain medicine (EXPAREL) given during heart surgery to see how it works in young children. The goal is to help control pain after surgery with fewer side effects.
Indianapolis, IndianaAges birth–6 years - NCT06206044Enrolling by invitation
Evaluating typical spinal blocks for cesarean delivery
This study looks at how well the standard spinal block works for cesarean sections. It aims to understand the typical effects to improve care for patients having a C-section.
Portland, OregonAges 15–55 - NCT06143306RecruitingPhase 4
Adding a second numbing shot for shoulder replacement pain
This study tests whether adding an extra numbing shot (pectoserratus block) to the standard shoulder block reduces pain after total shoulder replacement. It may help you recover more comfortably and use fewer pain medicines.
Minneapolis, MinnesotaAges 18–85 - NCT06004882Recruiting
Nerve stimulation vs. steroid injection for chronic knee pain
This study compares two treatments for long-term knee pain: a nerve stimulation device placed near the knee versus a steroid shot into the joint. The goal is to see which works better for pain relief.
Houston, TexasAges 18 years+ - NCT05979493RecruitingPhase 4
Nerve block for pain after fibroid surgery
This study tests whether a nerve block (QL block) can help with pain after surgery to remove uterine fibroids while keeping the uterus. It may be a good option if you are having a laparoscopic myomectomy and want to manage pain without strong opioids.
Beachwood, OhioAges 18–45 - NCT05793060RecruitingPhase 4
Compare two add-on medicines for neck nerve block comfort
This study compares dexmedetomidine versus dexamethasone as “extra” medicines added to bupivacaine during an intermediate cervical plexus nerve block. It aims to see which add-on helps with pain control and smoother comfort after the procedure.
Damanhūr, El-BeheiraAges 21–60 - NCT05216770RecruitingEarly Phase 1
Brain-scan study of voice dystonia and tremor
This early study uses brain and voice-related testing to better understand what is happening in the brain in people with laryngeal dystonia or voice tremor. The results may help scientists learn more about these conditions and how they differ from healthy voices.
Boston, MassachusettsAges 18–80 - NCT05734625RecruitingPhase 2
Nerve block injections for episodic migraine pain relief
This Phase 2 trial tests whether nerve block injections can reduce pain from episodic migraines. It may help some people who get frequent migraine attacks but are not also using certain migraine preventions or strong pain medicines.
Rochester, MinnesotaAges 18 years+
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Common questions
- Are there clinical trials for bupivacaine?
- Yes. Clin2 currently lists 198 recruiting bupivacaine studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bupivacaine trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bupivacaine trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.