Clinical trials
Caffeine clinical trials
Below are recruiting caffeine clinical trials, each written for real people, not researchers. We’re tracking 37 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05667246Enrolling by invitation
Caffeine and oral terbinafine for toenail fungus
This trial studies how drinking caffeine affects people who are starting oral terbinafine for toenail fungus. It may help explain whether caffeine changes side effects or effectiveness while you take the medicine.
New York, New YorkAges 18 years+ - NCT04570085RecruitingPhase 3
Caffeine treatment to improve thinking in Alzheimer’s disease
This trial tests whether changing caffeine intake can improve thinking and brain function in people with Alzheimer’s disease. You may qualify if you can follow a low-caffeine diet and have stable Alzheimer’s treatment and sleep/heart conditions.
AmiensAges 50 years+ - NCT07854431Recruiting
Measuring brain blood flow with light in healthy adults
This study uses a safe, non-invasive light-based technique called near-infrared spectroscopy (NIRS) to measure blood flow and oxygen in the brain. It aims to test a new monitoring device in healthy volunteers aged 20 to 40 to make sure it works correctly.
DüsseldorfAges 20–40 - NCT07854223Recruiting
Pre-run supplements during a 5 km treadmill run
This study tests whether certain nutritional supplements taken before running affect performance during a 5 km treadmill run. Participants will run at a set pace, and some will wear a continuous glucose monitor to track sugar levels.
St Louis, MissouriAges 18–35 - NCT06432504Recruiting
How coffee affects your energy use
This study looks at how coffee affects your body's energy use (metabolic rate). It may help researchers understand the effects of coffee on healthy adults.
Shenzhen, GuangdongAges 18–40 - NCT07710768RecruitingPhase 1
A study on how UBT251 affects certain drugs in people with extra weight
This study tests if a new medicine called UBT251 changes how the body processes caffeine, midazolam (a sedative), and warfarin (a blood thinner). It is for generally healthy adults with a Body Mass Index (BMI) between 27 and 40.
Cypress, CaliforniaAges 18–65 - NCT07710547Recruiting
TCP-600 supplement for football player performance
This trial tests whether a supplement called TCP-600 can help professional football players perform better in sprints, react faster, and feel less tired. If you are a healthy male player aged 18–36, you may be able to join.
KrakowAges 18–37 - NCT07665723RecruitingPhase 1
Study of afimkibart and other medicines in ulcerative colitis
This study looks at how afimkibart affects the way your body processes certain other medicines. It is for people with moderate to severe ulcerative colitis and helps researchers understand how to use this treatment safely.
Chula Vista, CaliforniaAges 18–60 - NCT06533137Recruiting
How your mind can influence the placebo effect
This trial studies how your awareness and personal beliefs affect the placebo effect—a real improvement in symptoms from a treatment that has no active medicine. Researchers are looking at healthy people to understand how the mind and body interact, which could help improve future treatments.
MilanAges 18 years+ - NCT07339722RecruitingPhase 1
Study of LY4515100 in healthy volunteers
This trial tests a new oral medication in healthy volunteers to see how it moves through the body and how safe it is. Taking part helps researchers understand how the drug works before it's studied in people with a certain condition.
Dallas, TexasAges 18–65 - NCT07324941Recruiting
EEG and caffeine timing in premature infants
This study uses EEG brain scans to find the best time to stop caffeine treatment in premature babies. Caffeine is given to help with breathing, and the goal is to see if brain activity can guide when to safely stop it.
BursaAges Up to 1 month - NCT07210099Recruiting
Olive Supplement and Fat Burning During Exercise
This study tests whether a supplement made from olives (OliPhenolia®) can help your body burn fat more efficiently during exercise. It may be a good fit if you're a healthy, active adult in the UK.
CambridgeAges 21 years+ - NCT06942117Recruiting
Caffeine's effect on understanding speech in noise
This trial tests whether drinking caffeine helps young adults hear speech better in noisy places. If you have normal hearing, don't smoke, and don't have certain health issues, you might be able to join.
Istanbul, IstanbulAges 18–30
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Common questions
- Are there clinical trials for caffeine?
- Yes. Clin2 currently lists 37 recruiting caffeine studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a caffeine trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a caffeine trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.