Clinical trials
Cancer Patients clinical trials
Below are recruiting cancer patients clinical trials, each written for real people, not researchers. We’re tracking 3,613 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06249282RecruitingPhase 1
Carfilzomib and sotorasib for KRAS G12C lung cancer
This trial tests a combination of two drugs: carfilzomib and sotorasib, for people with a specific type of advanced lung cancer (KRAS G12C mutation) who have already tried a KRAS-targeting drug that stopped working. The goal is to see if this new combination can shrink tumors or slow the cancer.
Duarte, CaliforniaAges 18 years+ - NCT06569147RecruitingPhase 1/Phase 2
Elranatamab for AL amyloidosis that has returned or not responded
This trial tests a drug called elranatamab for people with AL amyloidosis whose disease has come back or is not responding to treatment. The goal is to see if it can help control the disease.
New Haven, ConnecticutAges 18 years+ - NCT06317324Recruiting
SBRT vs. surgery for lung cancer with lobe spread
This study compares two treatments—stereotactic body radiation (SBRT) and surgery—for people whose non-small cell lung cancer has spread into the tissue between the lobes of the lung. The goal is to see which treatment leads to better long‑term results for this specific type of cancer.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06377527Recruiting
Tracking mesonephric-like adenocarcinoma cases
This study is creating a registry to collect information from patients with a rare type of gynecologic cancer called mesonephric-like adenocarcinoma (MLA) and related types. By joining, you help doctors learn more about this cancer to improve future care.
Houston, TexasAges 18 years+ - NCT06858735RecruitingPhase 2
HYPERION CCA: a Phase 2 Trial of Systemic Therapy With or Without Liver-directed Radiation Therapy for Patients With Advanced Intrahepatic Cholangiocarcinoma
Phase 2 trial evaluating systemic therapy ± liver-directed RT for advanced intrahepatic cholangiocarcinoma, with broad eligibility for patients who have received at least 4 cycles of gem/cis/durvalumab.
Houston, TexasAges 18 years+ - NCT07335302Recruiting
Study to improve comfort during brachytherapy device removal
This study looks at improving comfort and reducing distress when removing the internal device used in brachytherapy (a type of radiation) for gynecologic cancer. You will be asked to fill out surveys about how you feel before, during, and after the removal.
Houston, TexasAges 18 years+ - NCT06950086RecruitingPhase 1/Phase 2
TYK-00540 tablets for advanced solid tumors
This trial tests a new tablet, TYK-00540, alone or with another drug, for people with advanced solid tumors that have stopped responding to standard treatments. It aims to see if the drug can shrink tumors or slow their growth.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06567314RecruitingPhase 2
Study of Ivonescimab for advanced skin or prostate cancer
This study tests a new immunotherapy medicine, ivonescimab, in people with advanced skin cancer or advanced prostate cancer. It looks at how safe and effective the drug is.
Houston, TexasAges 18 years+ - NCT07566364RecruitingPhase 2
Mosunetuzumab for Chronic Lymphocytic Leukemia with Minimal Residual Disease
This study tests a new antibody drug called mosunetuzumab in patients with chronic lymphocytic leukemia (CLL) who have already tried other treatments and still have detectable leukemia cells in their bone marrow. The drug is designed to work in a way that might help your immune system fight the remaining cancer cells.
Houston, TexasAges 18 years+ - NCT03830229Recruiting
Long-term follow-up for people with BAP1 mutations
This study follows people with a harmful (deleterious) BAP1 gene change to learn how it affects health over time. It may help researchers better understand mesothelioma risk and the long-term outcomes for families with this genetic mutation.
Bethesda, MarylandAges 2 years+ - NCT02986048Recruiting
Proton Therapy Patient Registry
This registry collects information from people who receive proton beam treatment at the UH Proton Therapy Center. It helps the center learn from past and current patients, and may improve care planning in the future.
Cleveland, OhioAges Any age - NCT03655015Recruiting
Using patient tumor cells to test lung cancer treatment response
This study looks at lung cancer samples you provide to see how tumor cells respond to treatment. It may help researchers find better ways to choose treatments for lung cancer by testing response in a lab model.
San Antonio, TexasAges 18 years+ - NCT04474301Recruiting
Quality of life check for people with melanoma during COVID-19
This study looks at how people with melanoma are feeling during the COVID-19 pandemic, including quality of life. You may be asked to share information through surveys or study contact so the researchers can understand needs and concerns.
Houston, TexasAges Any age - NCT05091372RecruitingPhase 2
Maintenance treatment after transplant for newly diagnosed myeloma
This trial tests whether using belantamab mafodotin plus lenalidomide as long-term maintenance after an autologous stem cell transplant can keep multiple myeloma under control, guided by minimal residual disease (MRD). MRD is a very small amount of disease that may remain after transplant, and the study helps see if treating those patients better improves outcomes.
Houston, TexasAges 18 years+ - NCT05184803RecruitingPhase 2
Pre-surgery chemo for advanced stomach cancer with lymph spread
This Phase 2 study tests a combination chemotherapy regimen given before surgery for stomach cancer that cannot be fully removed (unresectable), including spread to lymph nodes. The goal is to shrink the cancer and improve control with a well-known set of medicines given in a specific order.
Seoul, SeoulAges 19 years+ - NCT05271916RecruitingPhase 1/Phase 2
New targeted drugs for advanced lung cancer with EGFR L858R
This study tests whether taking dacomitinib plus anlotinib as a first treatment can shrink or control advanced lung cancer that has the EGFR L858R mutation. It may help people who have not had any standard drug treatment yet, especially if their brain metastases are stable.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05529069RecruitingPhase 2
Testing pirtobrutinib plus venetoclax for relapsed mantle cell lymphoma
This Phase 2 trial tests how well the combination of pirtobrutinib and venetoclax works for people with mantle cell lymphoma that has come back or did not respond to treatment. It’s meant to help shrink the lymphoma and improve outcomes after prior therapies.
Houston, TexasAges 18 years+ - NCT05676450Recruiting
Test blood DNA to find lymphoma changes and leftover disease
This study checks a blood test that looks for small DNA fragments (“cell-free DNA”) to find cancer changes that could guide treatment in diffuse large B-cell lymphoma. It also looks for “minimal residual disease,” meaning tiny amounts of lymphoma that may remain after treatment, and whether this test works across community cancer centers in Texas.
Houston, TexasAges 18 years+ - NCT05989542RecruitingPhase 3
Study of vebreltinib for MET-mutated lung cancer
This study tests a new targeted pill (vebreltinib) for people with advanced non-small cell lung cancer that has a specific gene change (MET exon 14 mutation). It is for people who have not had much or any prior treatment. The goal is to see if this medicine can shrink tumors and improve outcomes.
Guangzhou, GuangdongAges 18 years+ - NCT06247826Recruiting
Why amivantamab stops working in certain lung cancers
This study looks at how and why lung cancers with a specific EGFR mutation (exon 20 insertion) become resistant to the drug amivantamab. It collects blood and tumor samples from patients whose cancer has progressed on amivantamab to better understand resistance.
BordeauxAges 18 years+ - NCT06828185Recruiting
Comparing two surgery methods for testicular cancer
This trial compares two ways of doing surgery (radical orchiectomy) for testicular cancer. One method is the standard approach and the other spares a layer of muscle tissue. The study looks at patient experiences and recovery.
Loma Linda, CaliforniaAges 18 years+ - NCT06437977RecruitingPhase 3
Pre-surgery treatment with radiation, immunotherapy, and chemo for stage II-III NSCLC
This trial tests whether combining radiation, an immunotherapy drug (toripalimab), and chemotherapy before surgery can help shrink tumors and improve outcomes in people with resectable stage II to III non-small cell lung cancer. It aims to see if this approach works better than standard chemotherapy alone.
ShanghaiAges 18–75 - NCT06448013RecruitingPhase 1
Ziftomenib with chemo for pediatric AML
This trial tests a new drug, ziftomenib, combined with two standard chemotherapies (venetoclax and gemtuzumab) for children and young adults with acute myeloid leukemia (AML) that has come back or not responded to treatment. It looks for specific genetic changes in the leukemia cells.
Houston, TexasAges 3–21 - NCT06511882RecruitingPhase 2
Stopping AML treatment after reaching remission with no detectable disease
This trial tests whether it is safe to stop taking a type of chemotherapy (azacitidine or decitabine) combined with venetoclax if you have acute myeloid leukemia (AML) and have achieved a remission with no trace of leukemia cells. If you have been on this treatment for less than a year and are not eligible for a stem cell transplant, you may be able to stop therapy and be monitored closely.
Tampa, FloridaAges 18 years+
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Common questions
- Are there clinical trials for cancer patients?
- Yes. Clin2 currently lists 3,613 recruiting cancer patients studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer patients trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer patients trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.