Lung Cancer Patients clinical trials

Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors

Study of Pembrolizumab + Pemetrexed + Platinum Chemotherapy With or Without Zoldonrasib as First Line Treatment in Metastatic Non-squamous RAS G12D-Mutated NSCLC

Tool to help lung cancer patients decide on adjuvant treatment

This study is testing a tool to help you and your doctor make decisions together about whether to have extra treatment after surgery for non-small cell lung cancer (stage 1B or higher). It only includes patients at Mayo Clinic in Rochester who are eligible for that extra treatment.

PD-L1 Inhibitor Rechallenge After Immunotherapy-Related Pneumonitis in Patients With Lung Cancer

Physical activity study for older cancer survivors with chronic pain

This study uses a smartphone program to encourage physical activity in older adults who have survived cancer and have ongoing pain. It aims to learn how to best help you move more and feel better.

Glowing dye to help surgeons see lung cancer during surgery

This trial tests a dye that makes lung cancer cells glow during surgery, helping surgeons remove more of the tumor. It's for people who are already scheduled for lung cancer surgery.

Combination therapy for STK11-mutant lung cancer

This trial tests a new drug (GT103) combined with the approved immunotherapy drug pembrolizumab for people with advanced lung cancer that has a specific genetic change (STK11). The goal is to see if adding GT103 helps control the cancer better than pembrolizumab alone.

Studying lung cancer in women

This study looks at the characteristics and trends of primary lung cancer in women diagnosed over the past 10 years. It helps researchers understand more about how lung cancer affects women.

Immunotherapy after surgery for lung cancer with no remaining cancer

This trial tests whether giving immunotherapy (durvalumab) after surgery can help prevent lung cancer from coming back if you already had a complete response to chemo and immunotherapy before surgery. It is for people with early-stage non-small cell lung cancer who had no cancer left after treatment.

Lung cancer screening adherence study

This trial looks at how to help people stick with lung cancer screening. You may qualify if you smoke now or have quit recently, have a heavy smoking history, and are healthy enough for screening.

A new treatment for lung cancer that has spread to the brain

This trial tests a combination of three drugs (datopotamab deruxtecan, carboplatin, and pembrolizumab) for people with a type of lung cancer called non-small cell lung cancer (NSCLC) that has spread to the brain and has not been treated before. The goal is to see if this combination can shrink tumors in the brain and elsewhere.

PET/CT scan for common solid tumors

This trial uses a new kind of PET/CT scan to take detailed pictures of solid tumors such as melanoma, liver, lung, breast, pancreatic, or ovarian cancer. The scan might help doctors find cancer more clearly.

Study of a new drug combined with irinotecan for small cell lung cancer

This study tests a new drug (cirtuvivint) combined with irinotecan, a common chemotherapy, for people whose small cell lung cancer has progressed after at least one prior treatment. The goal is to see if the combination helps control the cancer and whether it is safe.

Study of heart effects of radiation therapy using PET-CT for stage III lung cancer

This study looks at whether PET-CT scans can help detect heart damage caused by radiation therapy in patients with stage III lung cancer. If you're getting chemotherapy and radiation together, you may participate to help doctors find ways to reduce heart risks.

Pink and Pearl Lung Cancer Screening Study

This trial is testing a program called the Pink and Pearl Campaign to help more people get screened for lung cancer. If you're getting a mammogram at Christian Hospital and are between 50 and 80, you might be able to join.

Molecular testing for relapsed small cell lung cancer

This study uses tumor tissue to look for molecular (biologic) changes after your small cell lung cancer comes back. It may help doctors choose the most appropriate next treatment based on what the cancer’s biology shows.

Chemotherapy plus immunotherapy for advanced lung cancer

This study tests a combination of chemotherapy and immunotherapy in people with advanced non-small cell lung cancer that has spread or cannot be removed with surgery. The goal is to see how well this treatment works in patients with different levels of daily activity.

Exercise during immunotherapy for lung cancer

This study tests if adding a structured exercise program can help people with non-small cell lung cancer who are already on immunotherapy. It is for people who are not currently very active and are willing to travel to Dana-Farber Cancer Institute for some visits.

Two-Drug Lung Cancer Treatment Study

This trial tests a combination of two experimental drugs (AMT-116 and ivosidan) for patients with advanced lung cancer that cannot be removed by surgery. The study aims to see if this combination can help shrink tumors and improve survival.

Lung cancer surgery registry

This study collects information from people having surgery to remove a small part of the lung (segmentectomy) for early-stage lung cancer. It helps doctors learn more about this surgery and its outcomes.

Adding surgery to osimertinib for EGFR-mutant lung cancer

This trial tests whether removing the main lung tumor with surgery after 12 weeks of osimertinib (a targeted pill) helps control cancer better than osimertinib alone, for people with advanced non-small cell lung cancer that has an EGFR mutation and limited spread.

Study of PHN-012 for advanced solid tumors

This trial tests a new drug called PHN-012 for people with advanced colorectal, non-small cell lung, or pancreatic cancer who have already tried at least one standard treatment. The goal is to see if the drug can help shrink or slow tumor growth.

Immunotherapy plus local treatments for early spread lung cancer

This trial tests whether adding local treatments like radiation or surgery to standard immunotherapy can help people with lung cancer that has spread to a few spots. It aims to see if this combination improves control of the disease.

Lung cancer with brain spread: a surgical study

This trial looks at people with non-small cell lung cancer that has spread to the brain or the membranes around the brain. It aims to learn more about patients who are already scheduled for brain surgery, such as removing a tumor or placing a drain.