JMT101 plus osimertinib vs osimertinib for EGFR-mutant lung cancer
Treatments studied
Part of Cancer, Lungs & breathing clinical trials.
This trial tests a new combination of two targeted drugs (JMT101 and osimertinib) against osimertinib alone for people with advanced lung cancer that has an EGFR mutation. The goal is to see if the combination works better as a first treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have non-squamous non-small cell lung cancer that has spread and cannot be removed by surgery.
- You have not had any previous cancer treatment for advanced lung cancer (like chemotherapy or targeted therapy).
- Your tumor has an EGFR sensitive mutation (a specific change in the gene that helps cancer grow).
- You are able to do your daily activities without help (ECOG performance status 0 or 1).
- Your blood counts, kidney, and liver function are within certain limits (your doctor will check these).
- You do not have other gene changes that could be treated with a different targeted drug.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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