Clinical trials
Cancer Surgery clinical trials
Below are recruiting cancer surgery clinical trials, each written for real people, not researchers. We’re tracking 859 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04277858RecruitingPhase 2
Pre-surgery chemo plus robotic surgery for p16-positive throat cancer
This trial tests whether giving chemotherapy before robotic surgery works well for certain p16-positive oropharyngeal (throat) cancers. It aims to shrink or control the cancer and allow the surgeon to remove the tumor with clean margins while avoiding cancer spread beyond the neck.
Montreal, QuebecAges 18–80 - NCT03731442RecruitingPhase 3
Radiation plus chemotherapy for esophageal cancer that came back
This Phase 3 trial studies giving combined chemotherapy and radiation to treat esophageal cancer that has returned after earlier surgery and/or prior treatments. It may help control the cancer in the area where it comes back, especially when the surgical margins were not fully clear or the cancer is outside the original radiation field.
Beijing, Beijing MunicipalityAges 16–70 - NCT07227636RecruitingPhase 2
Immunotherapy for ctDNA-positive colorectal cancer after surgery
This trial tests two immunotherapy drugs, botensilimab and balstilimab, for people with colorectal cancer who have had surgery and chemotherapy but still have detectable cancer DNA in their blood. The goal is to see if these drugs can help clear the remaining cancer cells.
Basking Ridge, New JerseyAges 18 years+ - NCT07350928RecruitingPhase 3
Nasal spray before breast-saving surgery for calm wakefulness
This trial tests a nasal spray (dexmedetomidine) given before breast-conserving surgery to help you stay calm and comfortable while awake during the procedure. It aims to improve your recovery and waking experience after surgery.
TianjinAges 20–70 - NCT04890171Recruiting
Endoscopic removal vs surgery for early stomach cancer type
This trial compares two ways to treat early stomach cancer: removing it through an endoscope versus doing an operation. It’s meant for a specific stomach-cancer type (undifferentiated) that has not spread, to see which approach may be better.
Goyang-si, Gyeonggi-doAges 19–75 - NCT03051464RecruitingPhase 2/Phase 3
Testing two ways to boost radiation to prevent rectal surgery
This study looks at whether two different added “boosts” of radiation can work as well for rectal cancer patients, aiming to avoid or reduce the need for rectal cancer surgery. You would receive a specific combination of radiation (including brachytherapy) and chemotherapy, and your tumor’s location and size will determine if you can take part.
Dallas, TexasAges 18–80 - NCT06758830RecruitingPhase 2/Phase 3
Total neoadjuvant therapy vs surgery for rectal cancer
This trial tests whether a full course of chemotherapy and radiation before any surgery (called total neoadjuvant therapy) can help you avoid surgery and preserve your rectum. It is for people with a specific early stage of rectal cancer that has not spread.
VilniusAges 18 years+ - NCT01416714Recruiting
Tissue sample collection during cancer surgery or biopsy
This study is collecting tissue samples from people with certain cancers while they have surgery or a biopsy. It may help researchers learn more about these cancers and improve future diagnosis and treatment.
Chicago, IllinoisAges Any age - NCT06637215Recruiting
Day surgery for colorectal cancer
This study tests whether a same-day surgery approach for colorectal cancer is safe and effective. It uses small incisions and special pain management to help you recover faster at home with a caregiver nearby.
Shenyang, LiaoningAges 18–75 - NCT06716073Recruiting
Endoscopic vs standard breast-conserving surgery after chemo
This study compares two types of breast-conserving surgery for women who have already had chemotherapy before their operation. It aims to see if using a tiny camera (endoscope) leads to equally good long-term results as standard breast-conserving surgery.
Guangzhou, GuangdongAges 18–75 - NCT05454280RecruitingPhase 3
Manage surgical risk after high-risk cancer operations
This study looks at a “risk-based plan” to help guide care after major cancer surgery, aiming to improve recovery and outcomes. You may be in the study when you’re about to have elective (planned) high-risk cancer surgery and then again just before hospital discharge.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05848609Recruiting
Quality of life study for older adults having robotic colon surgery
This study looks at how older people feel and function after robotic surgery for colorectal cancer. It may help doctors understand what to expect and how to better support quality of life during recovery.
BrusselsAges 70 years+ - NCT04063527RecruitingPhase 3
Stage I ovarian cancer treatment after surgery
This trial studies whether an additional treatment after surgery can help people with early-stage epithelial ovarian cancer live longer and stay well for more time. It is meant for patients who had a detailed staging operation and are able to start treatment within 8 weeks.
Nagakute-shi, Aichi-kenAges 20 years+ - NCT05245877RecruitingPhase 4
Preventing blood clots before and after pancreatic surgery
This study compares two approaches to preventing blood clots around the time of pancreatic surgery. It may help lower the risk of dangerous clotting events after surgery, especially for people who are high risk.
TorontoAges 18–120 - NCT05428358Recruiting
MRI helps choose which pancreatic cancer patients can have surgery
This trial studies whether adding an MRI scan improves the selection of people with pancreatic cancer who may benefit from surgery. It focuses on patients without liver spread and with tumors that are borderline or likely removable.
AalborgAges 18–99 - NCT06737822RecruitingPhase 3
Surgery first vs chemo then surgery for oral cancer
This trial compares two approaches for treating oral cancer: having surgery right away or having chemotherapy first followed by surgery. It aims to find which sequence leads to better outcomes for patients.
Bhubaneswar, OdishaAges 18–75 - NCT07366515Recruiting
Virtual reality to reduce anxiety before cancer surgery
This study tests if using virtual reality before surgery can help lower anxiety in cancer patients. You would participate while waiting for your operation at the hospital.
Winnipeg, ManitobaAges 18 years+ - NCT06930378Recruiting
Breast skin feeling after DIEP flap reconstruction
This trial compares three surgical techniques to see which one best preserves or improves skin feeling after breast reconstruction with a DIEP flap (using your own tissue to rebuild the breast). You may join if you are having this type of reconstruction and do not have nerve problems or smoke.
Geneva, Canton of GenevaAges 18–80 - NCT06314646Recruiting
Comparing two ways to reconnect the intestine after rectal cancer surgery
This study compares two ways of reconnecting the intestine after rectal cancer surgery. It looks at a newer method called TTSS against the standard double-stapled technique.
Rozzano, MIAges 18 years+ - NCT06732193Recruiting
Fissios App for recovery after lung cancer surgery
This trial tests whether using a smartphone app (Fissios) after lung cancer surgery helps you recover with fewer complications. If you are scheduled for lung surgery for non-small cell lung cancer and have a smartphone, you may be eligible.
Madrid, MadridAges 18 years+ - NCT06447532Enrolling by invitation
Machine learning to track inflammation in breast cancer
This study uses a computer program to look at blood test results from women treated for breast cancer. The goal is to see if patterns in inflammation markers can help predict outcomes.
Buenos Aires, Buenos AiresAges 18–75 - NCT06135571Recruiting
Lymph node patterns in left colon and rectal cancer
This study looks at how colon and rectal cancer on the left side spreads to nearby lymph nodes (No.253). It is for people who have had laparoscopic surgery and whose cancer is still only in the colon or rectum. The goal is to better understand these patterns to help guide future treatment.
Beijing, Beijing MunicipalityAges 18–75 - NCT04389086RecruitingPhase 3
Chemotherapy before surgery for recurring rectal cancer
This trial tests an “induction chemotherapy” treatment before surgery for people whose rectal cancer has come back in the local area. The goal is to shrink/control the cancer early and improve outcomes after treatment.
GhentAges 18 years+ - NCT06631872Recruiting
Surgery school prehabilitation via telehealth for lung or abdominal cancer
This trial tests a telehealth program to help you get ready (prehab) before lung or major abdominal cancer surgery. It aims to improve your recovery and might be easier than attending in person.
New Lambton Heights, New South WalesAges 18 years+
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Common questions
- Are there clinical trials for cancer surgery?
- Yes. Clin2 currently lists 859 recruiting cancer surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.