Surgery first vs chemo then surgery for oral cancer
Part of Cancer, Mouth & dental clinical trials.
This trial compares two approaches for treating oral cancer: having surgery right away or having chemotherapy first followed by surgery. It aims to find which sequence leads to better outcomes for patients.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have newly diagnosed, untreated oral cancer confirmed by biopsy or cytology.
- Your cancer is at a certain stage (T1 to T4a, with lymph nodes N2 or N3) but has not spread to other parts of the body.
- You are in good enough health to undergo surgery, with a performance score of 0 to 2 (able to care for yourself).
- You do not have a known allergy to cisplatin or a condition that prevents you from receiving radiation therapy.
- Your organ function is adequate, with normal blood counts, liver and kidney tests.
- You are not pregnant, have no significant hearing loss, no recent major weight loss (over 15% in 6 months), and no active HIV, hepatitis B, or C infection.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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