Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,278 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06712745RecruitingEarly Phase 1
Personalized lung cancer radiation therapy study
This trial tests a new approach to radiation therapy for central lung cancers, giving high doses in very short bursts to see if it's safe and effective. It may be an option for people whose tumors are not too large and are in a specific central location.
Dallas, TexasAges 18 years+ - NCT06713421Recruiting
Pronase to improve stomach cleanliness during endoscopy
This study tests whether a medicine called pronase, taken before an upper endoscopy (a scope test to look at your stomach), helps keep the stomach lining cleaner so the doctor can see better. If you are having a routine upper endoscopy, this might help make the exam more accurate.
ShanghaiAges 18–70 - NCT06718543RecruitingPhase 2
Short-course radiation with AK112 for rectal cancer before surgery
This trial tests whether combining short-course radiation with an immune therapy drug (AK112) plus chemotherapy before surgery is better than radiation alone for locally advanced rectal cancer. It aims to shrink tumors and improve outcomes without needing stronger treatments later.
Chongqing, Chongqing MunicipalityAges 18–80 - NCT06728878Recruiting
Lymph node spread after total stomach removal for stomach cancer
This study looks at where cancer spreads in the short stomach area after total stomach removal surgery. It aims to understand lymph node and tumor deposits better to help guide future treatment decisions.
Hangzhou, ZhejiangAges 18–85 - NCT06731907RecruitingPhase 2
Keytruda with or without chemo for advanced lung cancer
This trial tests a new combination of drugs (Keytruda with or without chemotherapy) to see if it works better for advanced lung cancer. It's for people who haven't had immunotherapy or chemotherapy for their cancer that has spread.
Lexington, KentuckyAges 18 years+ - NCT06733038RecruitingPhase 3
Chemo plus Avastin with or without Tecentriq for advanced colorectal cancer
This trial tests whether adding the immunotherapy drug atezolizumab (Tecentriq) to standard chemotherapy (FOLFOXIRI) and bevacizumab (Avastin) is more effective as a first treatment for people with a specific type of metastatic colorectal cancer that has a high immune score and is mismatch repair proficient.
Brescia, BSAges 18–75 - NCT06736847Recruiting
Lymph node spread in stomach cancer surgery
This trial looks at how stomach cancer spreads to lymph nodes and other tissues behind the stomach during surgery. It may help doctors understand which patients need more extensive surgery.
Hangzhou, ZhejiangAges 18–85 - NCT06756074RecruitingPhase 2
Surgical glue study for Whipple surgery patients
This trial compares two ways of reconnecting the pancreas after a Whipple surgery for cancer. It tests whether using a special surgical glue (Glubran2) helps reduce leaks and improve healing.
MinyaAges 18–75 - NCT06793332RecruitingPhase 2
Ivonescimab and Trodelvy for breast cancer with brain metastases
This trial tests two drugs (Ivonescimab and a Trop2 ADC) for people with triple-negative breast cancer that has spread to the brain. It aims to see if this combination can shrink brain tumors and help patients live longer.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06856837RecruitingPhase 2
Fruquintinib and Tislelizumab for advanced colorectal cancer
This trial tests a combination of two drugs, fruquintinib and tislelizumab, for people with a specific type of advanced colorectal cancer that has not spread to the liver. It is for those whose cancer is stable in certain DNA repair systems (MSS/pMMR) and who have already tried other treatments.
LinzAges 18 years+ - NCT06901817RecruitingPhase 2
Study of pemetrexed plus nivolumab for lung cancer that has spread to the lining of the brain
This trial tests a combination of two drugs, pemetrexed and nivolumab, given directly into the fluid around the brain and spinal cord. It is for people with a specific type of lung cancer (non-squamous non-small cell) that has spread to the lining of the brain and has not responded to other treatments.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06905301Recruiting
Study on breast cancer medication with a mobile app
This study compares how well breast cancer patients take their medication (ribociclib) with or without using a mobile app. It aims to see if the app helps patients stick to their treatment plan.
Pskov, RussiaAges 18–90 - NCT06929013Recruiting
Blood marker study for colorectal cancer spread to belly
This study looks at how certain blood markers (nucleosome and CTCF) clear from the body in people with colorectal cancer that has spread to the lining of the belly. It also includes people with other conditions to compare. The goal is to learn more about these markers to help guide treatment.
Pierre-BéniteAges 18 years+ - NCT06935305Recruiting
Testing a faster method to find cancer in sentinel lymph nodes
This trial compares a fast lab test (OSNA) with standard microscope checks to see which better finds cancer in the first lymph node (sentinel node) during surgery for early-stage endometrial cancer. It aims to improve accuracy and speed while avoiding unnecessary lymph node removal.
Rome, ItalyAges Any age - NCT06940388RecruitingPhase 2
Immunotherapy plus standard treatment for rectal cancer
This trial is testing whether adding the immunotherapy drug tislelizumab to standard total neoadjuvant treatment (chemotherapy and radiation before surgery) can improve outcomes for people with locally advanced rectal cancer. The goal is to see if the combination helps shrink the tumor more than standard treatment alone.
MainzAges 18 years+ - NCT06945978Recruiting
Testing a blood test to predict treatment response in advanced pancreatic cancer
This study looks at a special blood test (miRNA panel) to see if it can help predict how well treatment works for people with advanced pancreatic cancer. If you are starting FOLFIRINOX for the first time, you may be able to join.
São Paulo, São PauloAges 18 years+ - NCT06995833Recruiting
Durvalumab with or without Olaparib for endometrial cancer
This trial collects safety information on the standard use of Durvalumab (with or without Olaparib) in people with endometrial cancer in Korea. It helps doctors confirm the real-world effects of these approved treatments.
SeoulAges Any age - NCT07035002RecruitingPhase 1
PD-1 knockout TILs for advanced colorectal cancer
This trial tests a new therapy where immune cells (TILs) from your tumor are modified to fight cancer more effectively. It's for people with advanced colorectal cancer who can't get standard treatments.
Shanghai, None SelectedAges 18–70 - NCT07036731Recruiting
Urine test study for second bladder surgery
This trial compares the need for a second surgery for people with early-stage bladder cancer. It uses a simple urine test to see if the test can help decide whether a second operation is necessary, which could save some patients from an extra procedure.
Nanjing, JiangsuAges 18–80 - NCT07040657Recruiting
Comparing injection techniques for cervical lymph node mapping in endometrial cancer
This trial tests two different injection methods in the cervix to help map lymph nodes for endometrial cancer. The goal is to find which technique works better for staging, using a dye that helps surgeons see the lymph nodes during surgery.
AnkaraAges 18–75 - NCT07046923RecruitingPhase 1
A study of LY4175408 for advanced cancer
This trial tests a new targeted drug (LY4175408) for people with certain advanced solid tumors (lung, endometrial, or triple negative breast cancer) who have already tried standard treatments. The goal is to see if the drug is safe and effective.
Stanford, CaliforniaAges 18 years+ - NCT07056010Recruiting
Minimally invasive surgery for advanced stomach cancer after chemoimmunotherapy
This trial tests a minimally invasive surgery for stomach cancer that has spread to lymph nodes near the main blood vessels (para-aortic area). The surgery is done after a combination of chemotherapy and immunotherapy to shrink the tumor. It aims to see if this approach is safe and effective.
Nanjing, JiangsuAges 18–80 - NCT07058571Recruiting
Exercise program for veterans with blood cancer
This study tests a lifestyle program delivered by phone or video for veterans with blood cancer. It aims to see if gentle exercise two times a week can improve your well-being.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07075679Recruiting
AI vs double reading for breast cancer screening
This study compares a single radiologist reading your mammogram with help from artificial intelligence (AI) to the standard method of two radiologists reading it. The goal is to see if AI-assisted reading is just as good at finding cancer while saving time and resources.
OlomoucAges 45–69
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,278 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.