Clinical trials
Cancer clinical trials
Below are recruiting cancer clinical trials, each written for real people, not researchers. We’re tracking 12,855 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05904119RecruitingPhase 3
Lomustine with or without re-irradiation for recurring glioblastoma
This trial studies whether adding repeat radiation (called re-irradiation) to the chemotherapy medicine lomustine can slow or control glioblastoma that has returned or progressed after standard treatment. It’s designed for people whose tumor comes back at least 6 months after their last radiation.
InnsbruckAges 18 years+ - NCT05907759RecruitingPhase 2
Daratumumab for HIV-related lymphomas and Castleman disease
This trial tests a drug called daratumumab for people with certain HIV-related blood cancers (primary effusion lymphoma, plasmablastic lymphoma) or a related condition called multicentric Castleman disease that has come back or not improved after standard treatment. The drug targets a protein on cancer cells to help the immune system attack them. It might be a new option when standard chemotherapy isn't working or isn't suitable.
Bethesda, MarylandAges 18–120 - NCT05886049RecruitingPhase 1
Testing a menin drug with standard chemo for newly diagnosed AML
This early-phase study tests a menin inhibitor drug (SNDX-5613) combined with standard induction chemotherapy (daunorubicin plus cytarabine) in newly diagnosed AML with specific gene changes (NPM1 or FLT3 status, or MLL/KMT2A or NUP98). It may help patients whose AML has these genetic features respond better to intensive treatment.
Orange, CaliforniaAges 18–75 - NCT05886036RecruitingPhase 2
Comparing rituximab vs mosunetuzumab for NLPHL
This trial compares two immunotherapy drugs, rituximab and mosunetuzumab, to see which works better for people with nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) who need treatment. It's for both newly diagnosed and previously treated patients.
Duarte, CaliforniaAges 18 years+ - NCT05893940Recruiting
Gentle physical stimulation during blood cancer transplant
This trial tests whether a low-intensity mechanical (physical) stimulation is safe and helpful for people with certain blood cancers who are about to have a transplant. It may affect how you do during or after treatment, and participation is voluntary with informed consent.
Buffalo, New YorkAges 18 years+ - NCT05905146Recruiting
Personalized opioid plan to shorten treatment time
This trial tests whether a personalized medication plan can help patients with short-term, non-cancer muscle or joint pain need strong opioid medicine for a shorter time. It’s aimed at improving how long treatment lasts while still managing pain.
LilleAges 18 years+ - NCT05884723Recruiting
Ketogenic diet before liver surgery for fatty liver
This trial tests whether a ketogenic (very low-carb) diet before liver surgery can reduce fat in the liver. It is aimed at people with colorectal liver metastases who already have fatty liver seen on scans or biopsy.
London, OntarioAges 18 years+ - NCT05879211Enrolling by invitation
Care learning lab for Duke Health patients
This trial is a “learning laboratory” that studies how best to provide goal-focused care. It may help improve care experiences for Duke Health patients, based on what the study learns.
Durham, North CarolinaAges 18 years+ - NCT05879146RecruitingPhase 2
Nirogacestat for desmoid tumors with tumor growth monitoring
This Phase 2 study tests nirogacestat (a targeted medicine) in people with desmoid tumors that are growing. It also studies how tumors respond—or don’t respond—by using repeated tumor scans and sometimes repeated tumor biopsies.
Houston, TexasAges 18 years+ - NCT05885048Recruiting
Testing how cancer treatments affect future fertility
This study looks at how treatments that can harm ovaries or testicles (like certain chemotherapy, radiation, and immune therapies) may affect fertility. It may help you and others by measuring hormone levels (and in some cases sperm) before and during/after treatment.
BernAges 14–50 - NCT05903131RecruitingPhase 2
Lifestyle program to help keep the uterus in early cancer
This Phase 2 study tests whether a lifestyle transformation can help treat complex atypical endometrial hyperplasia or early (grade 1) endometrial cancer without removing the uterus. It may help support uterine preservation for people who want to keep fertility or avoid hysterectomy.
St Louis, MissouriAges 18 years+ - NCT05909501Recruiting
Study of geriatric checkups for new AML treatment plans
This study looks at whether geriatric (age-related health) evaluations help doctors choose better treatment for newly diagnosed AML (a type of leukemia). It may help translate older adults’ needs into a clearer, safer treatment plan.
Philadelphia, PennsylvaniaAges 50 years+ - NCT05893888RecruitingPhase 2/Phase 3
Testing three investigational drugs for mouth and lung cancers
This trial tests whether PRV111, PRV211, and PRV131 are safe and work better than expected for certain mouth (lip/oral cavity) cancers and lung cancers. It may help by trying a new approach given directly to the tumor and then monitoring how well it shrinks and how safe it is.
Duarte, CaliforniaAges 18–100 - NCT05873231Recruiting
Gut microbiome study for diarrhea after anti-cancer treatment
This trial looks at how changes in the gut (microbiome) relate to diarrhea that can happen after starting anti-cancer therapy. It may help doctors better predict and manage treatment-related diarrhea.
GrazAges 18 years+ - NCT05875870Recruiting
Bright light and exercise program for lung or esophageal cancer
This trial tests whether a structured bright-light exposure routine combined with a specific exercise program can help people with newly diagnosed lung or esophageal cancer. You may be eligible if you’re in early-to-middle cancer stages and able to safely participate in walking-based activities.
Taipei City, TaipeiAges 20 years+ - NCT05862285RecruitingPhase 3
Rollover trial for people already on Roche study treatment
This is a “rollover” study for people who were already taking a Roche (or Genentech) cancer study medicine. It checks whether continuing the same study treatment (when commercial options aren’t available) can keep helping you.
CharleroiAges Any age - NCT05855200RecruitingPhase 3
Dostarlimab around surgery for certain untreated colon cancers
This trial studies dostarlimab given around the time of colon cancer surgery for people with untreated, resectable (operable) stage T4N0 or stage III colon cancer that has specific tumor markers. It may help shrink or eliminate the cancer before or after surgery by boosting the immune response.
Tucson, ArizonaAges 18 years+ - NCT05865535RecruitingPhase 1
Dose study of AV-380 for cancer-related weight loss
This Phase 1 trial tests a new drug (AV-380) in people with solid tumor cancer who are losing weight and muscle because of cancer. It mainly helps researchers find a safe dose and see how the body responds, and it may offer a new option for cancer-related cachexia.
Beverly Hills, CaliforniaAges 18 years+ - NCT05876390Enrolling by invitation
Regional anesthesia to reduce long-term breast surgery pain
This trial studies whether a pain-control technique called regional anesthesia during certain breast surgeries can lower chronic (long-lasting) pain after surgery. It may help improve comfort and quality of life for people at risk of ongoing pain after their breast operation.
Milan, LombardyAges 18 years+ - NCT05864196RecruitingPhase 1
Testing two-shot prostate radiation with MRI-guided planning
This early-phase study tests a prostate radiation approach given in two treatments, planned using MRI. It’s designed for men with lower-to-intermediate risk prostate cancer and aims to see if this method is safe and works well.
Mineola, New YorkAges 18 years+ - NCT05858424Recruiting
Day hospital program to improve young cancer survivors’ well-being
This study tests a structured “end-of-treatment” day hospital program to improve quality of life for adolescents and young adults after cancer treatment. You may be offered follow-up and supportive care soon after finishing treatment to help you feel better physically and emotionally.
LyonAges 15–25 - NCT05851924RecruitingPhase 2
Nalirifox plus radiation for nonmetastatic pancreatic cancer
This trial studies Nalirifox (chemotherapy) given together with radiation therapy for pancreatic ductal adenocarcinoma that has not spread to distant organs. It may help shrink the cancer and improve local control, especially when surgery is not an option right now.
Basking Ridge, New JerseyAges 18 years+ - NCT05877456Enrolling by invitation
Checking a polyp-removal scoring tool for doctors
This study tests and confirms a scoring tool (GPAT) that helps describe how well doctors perform polyp removal during endoscopy. It may help standardize training and assessment, which can improve consistency in care.
Ghent, GentAges 18–100 - NCT05848557Recruiting
Mobile app study for cervical cancer screening and education
This study tests a mobile health tool (an app) and related surveys to improve knowledge and screening awareness for cervical cancer, including HPV risk and acceptability. It involves people working in cervical cancer screening and women in specific communities, with participation based on consent and eligibility for screening.
Kisumu, Kisumu CountyAges 18 years+
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Common questions
- Are there clinical trials for cancer?
- Yes. Clin2 currently lists 12,855 recruiting cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Beyond the search
We also like to point to nonprofits doing real good in this area. We aren’t affiliated with them — we just admire the work.
- Stand Up To CancerPeople facing cancer across many types, through the research that leads to better treatments.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.