Clinical trials
Cannabis Use Disorder clinical trials
Below are recruiting cannabis use disorder clinical trials, each written for real people, not researchers. We’re tracking 156 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07063589Recruiting
Cannabis use patterns in young adults
This study looks at how young adults (ages 18–24) use cannabis and how it relates to their health and social life. If you join, you'll answer questions through your mobile phone over time, which helps researchers understand patterns and effects.
Montreal, QuebecAges 18–24 - NCT07732062Recruiting
Emotion-focused therapy for chronic pain patients using medical cannabis
This study tests a new type of talking therapy (vEAET-H) to see if it helps people with chronic pain who are already using medical cannabis. The goal is to find out if adding this therapy can improve pain and well-being.
Tel AvivAges 18 years+ - NCT06104280Recruiting
How opioid addiction meds affect sleep and eyes
This study tests how three common medications for opioid use disorder (methadone, buprenorphine, and naltrexone) affect eye function, sleep, and daily body rhythms. It may help find ways to improve treatment for opioid addiction.
Birmingham, AlabamaAges 18–80 - NCT06457841Recruiting
Stress and Resilience in Afro-Descent Adults
This study looks at how stress and resilience affect people who use alcohol or cannabis to cope. It's for adults of Afro-descent who have used alcohol or cannabis at least a few times recently and are not in treatment for substance use.
Dallas, TexasAges 18–30 - NCT03332966Recruiting
Study of teens’ experiences in mental health care
This study looks at how young people experience mental health clinic care and how that relates to health outcomes. You may be invited if you are starting care in an adolescent mental health clinic.
HelsinkiAges 15–18 - NCT05883358Recruiting
Treating kratom withdrawal with clonidine or buprenorphine
This trial studies medicines (clonidine and/or buprenorphine) to help manage kratom dependence and kratom withdrawal symptoms. You may be asked to regularly track withdrawal symptoms in diaries to help the study team monitor safety and response.
Surrey, British ColumbiaAges 20–99 - NCT01730781Recruiting
PET scan study to image cannabinoid receptors in the brain
This study uses a special brain scan (PET) to measure cannabinoid receptors—areas in the brain that interact with cannabis-like chemicals. It may help researchers better understand how these receptors relate to conditions such as schizophrenia, PTSD, opioid use disorder, or early psychosis risk.
New Haven, ConnecticutAges 18–55 - NCT06030154Recruiting
Boosting positive feelings for people with alcohol use disorder
This study tests a program designed to help people with alcohol use disorder who also struggle with low mood or anxiety. It aims to increase positive emotions, which may make it easier to reduce drinking.
Tulsa, OklahomaAges 18–65 - NCT06218056RecruitingPhase 2
CBD for reducing cigarette smoking in a treatment center
This study tests whether a daily dose of cannabidiol (CBD) can help people who smoke at least 5 cigarettes a day cut down or quit. It is for people staying at a treatment center in Los Angeles where cannabis use is not allowed.
North Hollywood, CaliforniaAges 18–65 - NCT06379984RecruitingPhase 2
Quick-start buprenorphine for opioid addiction with fentanyl use
This trial tests a way to quickly start buprenorphine (a medication for opioid addiction) in an outpatient clinic for people who use fentanyl. It aims to make starting treatment easier and faster, without needing to go through full withdrawal first.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05838274Recruiting
Study of alcohol effects and brain scans in bipolar disorder
This study gives a controlled amount of alcohol and uses brain MRI scans to understand how alcohol affects people with bipolar disorder. It may help researchers find brain and behavior patterns that explain differences in alcohol responses.
Austin, TexasAges 21–26 - NCT06743373Recruiting
Cannabis and sleep in young adults
This study looks at how cannabis affects sleep, daily rhythms, and sensitivity to light in young adults. You would either stop using cannabis for 4 weeks (if you are a regular user) or serve as a non-user control, to compare sleep patterns.
Pittsburgh, PennsylvaniaAges 18–25 - NCT05786157Recruiting
Couples alcohol and safety support for drinking and relationship harm
This study tests a patient-focused approach to help couples where alcohol misuse and relationship physical harm may be happening. You may be asked to take part in sessions focused on safety, coping, and relationship communication, and some components may include controlled alcohol exposure.
Charleston, South CarolinaAges 21 years+ - NCT06967051Recruiting
Smartphone test of pupil response after cannabis use
This study uses a smartphone app to measure how your pupils react to light after using cannabis. It aims to see if the app can detect recent cannabis use, which could help develop a quick, non-invasive test.
London, OntarioAges 21 years+ - NCT06588582Recruiting
How cannabis influences perception and feelings
This study looks at how smoking cannabis affects your perception and emotions. It aims to understand why some people use cannabis to cope with stress or negative feelings.
Boulder, ColoradoAges 21–65 - NCT05219175RecruitingPhase 2
MDMA therapy for PTSD and opioid addiction after childbirth
This Phase 2 study tests whether MDMA-assisted therapy can reduce symptoms of PTSD and help with opioid use disorder in people after childbirth. You must be on a stable, low enough dose of methadone or buprenorphine and be able to follow study rules, including therapy sessions and safety monitoring.
Albuquerque, New MexicoAges 18 years+ - NCT07196462Recruiting
Brain stimulation to reduce cannabis craving in schizophrenia
This study tests if a non-invasive brain stimulation technique can help reduce cravings for cannabis in people with schizophrenia. It aims to see if this approach can improve outcomes for those who use cannabis and have a psychotic disorder.
Nashville, TennesseeAges 18–65 - NCT06636227RecruitingPhase 1
Diclofenac dose study for alcohol use disorder
This study tests whether different doses of diclofenac, an anti-inflammatory drug, can help people reduce heavy drinking. It looks at how the drug affects drinking patterns and overall health.
Catonsville, MarylandAges 21–65 - NCT07202351Recruiting
Sleep support for quitting smoking or cannabis
This trial tests whether adding sleep-focused help to standard quit-smoking or quit-cannabis therapy improves your chances of success. It is for people who are not already being treated for sleep problems.
Paris, Île-de-France RegionAges 18 years+ - NCT06580457Recruiting
Personalized smartphone program for Veterans with substance use
This study tests a personalized smartphone program to help Veterans reduce harmful substance use. It uses daily surveys and feedback to support healthier habits.
Minneapolis, MinnesotaAges 18 years+ - NCT06206252Recruiting
Can Medical Cannabis Help Reduce Opioid Use?
This study tests whether medical cannabis can help people who take opioids for long-term pain reduce their opioid use. Participants will either use medical cannabis or continue without it for 3 months.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06863740Recruiting
Cannabis for Restless Legs Syndrome
This study tests whether cannabis can help people with Restless Legs Syndrome that has not improved with standard treatments. If you have RLS and other treatments haven't worked well, you may be able to join.
Toronto, OntarioAges 25 years+ - NCT07362407Enrolling by invitation
Cannabinoid treatment study for patients in Brazil
This study tracks how cannabis-based medicines work in real life. It looks at how people feel and function while using these treatments prescribed by their doctor.
Florianópolis, Santa CatarinaAges 18 years+ - NCT07001878RecruitingPhase 4
Cannabis Strength and Brain Health in Early Psychosis
This trial studies how different strengths of cannabis affect the brain's white matter in people with early psychosis. It may help doctors understand which cannabis potencies are less harmful for young adults with psychosis.
St. John's, Newfoundland and LabradorAges 18–25
Hear when a new Cannabis Use Disorder trial opens
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Common questions
- Are there clinical trials for cannabis use disorder?
- Yes. Clin2 currently lists 156 recruiting cannabis use disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cannabis use disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cannabis use disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.