Clinical trials
Cardiac clinical trials
Below are recruiting cardiac clinical trials, each written for real people, not researchers. We’re tracking 1,308 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05412862Recruiting
Improving mood after a recent heart event
This study looks at whether increasing positive emotions after an acute heart problem (like a heart attack or unstable angina) can help patients feel and function better. You may be eligible if you had a recent heart event and are not currently getting enough physical activity.
Boston, MassachusettsAges 18–95 - NCT05423665Recruiting
Ultrasound check to spot early growth problems in twin pregnancies
This study uses a special ultrasound method (speckle tracking echocardiography) to look for early signs that a twin pregnancy may have impaired fetal growth. It may help clinicians detect problems earlier and better understand how twin babies’ hearts and growth are affected.
GhentAges 18–45 - NCT05426408Recruiting
Test study for heart attacks without blocked arteries
This study looks at people who may have MINOCA (heart attack symptoms with no major artery blockage) or takotsubo syndrome (a temporary stress-related heart condition). The goal is to better understand these causes and how they should be diagnosed and treated.
StockholmAges 35–79 - NCT05428631Recruiting
Monitoring device tested in severe kidney and heart failure
This study checks how safe a small heart-pressure monitoring device is for people with advanced heart failure and severe kidney problems. It looks at whether doctors can continuously track heart filling/pressure to help manage symptoms and reduce risks.
Nîmes, GardAges 18–85 - NCT05439031RecruitingPhase 2
Stereotactic radiation to reduce recurrent dangerous heart rhythm episodes
This Phase 2 study tests a precise form of radiation therapy to control recurrent ventricular tachycardia (VT), a dangerous fast heart rhythm. It may help people whose VT keeps coming back despite heart medicines and/or ablation, especially when ablation is not possible.
Amsterdam, North HollandAges 18 years+ - NCT05447559RecruitingPhase 4
Testing how long to give antibiotics after heart surgery
This study looks at how long patients should receive an antibiotic after certain types of heart surgery, to help prevent infections. It may help find the best “duration” of antibiotic prophylaxis after surgery through the breastbone (median sternotomy).
Dallas, TexasAges 18 years+ - NCT05450328RecruitingPhase 2
Breathing medicine to help heart-lung machine separation after surgery
This Phase 2 trial tests whether inhaled medicines (milrinone and epoprostenol) can make it easier to separate from the heart-lung machine during cardiac surgery. It may help reduce the risk of a difficult transition off the machine for the right patients.
Montreal, QuebecAges 18 years+ - NCT05470335Recruiting
Nurse-led heart procedure setup for suspected heart artery disease
This study checks whether a nurse-led technique for placing a sheath (a small tube used during a heart test/procedure) works safely in people suspected of blocked heart arteries. If you qualify, your care team will guide the process and compare how it goes with standard approaches.
Roskilde, DanmarkAges 18 years+ - NCT05476991RecruitingPhase 3
Low-dose colchicine plus ticagrelor to prevent repeat stroke
This Phase 3 study tests whether low-dose colchicine added to ticagrelor (a blood-thinning medicine) helps prevent another ischemic stroke in people whose first stroke was caused by clogged arteries. It aims to lower the risk of repeat stroke after recovery from a recent event.
Paris, ParisAges 18 years+ - NCT05479669Recruiting
Testing detailed heart scans in people with heart failure symptoms
This study looks at whether doing very detailed heart testing helps understand and guide care for people with heart failure with preserved pumping strength. You may be eligible if you’re an adult with specific symptom levels, recent heart-failure-related visits, and matching scan and blood test results.
GroningenAges 18 years+ - NCT05487612Recruiting
MiECC heart-lung machine vs standard bypass during heart surgery
This trial compares a newer heart-lung machine setup (MiECC) with the usual bypass technique during certain heart operations. It may help see whether MiECC changes outcomes like the need for blood transfusions or recovery after surgery.
TorontoAges 18–85 - NCT05491655Recruiting
Testing a new pacing approach in some heart failure patients
This study looks at whether a high-intensity “His bundle” heart pacing method can help people with heart failure who have a specific heart rhythm pattern on ECG. It likely aims to improve heart pumping and symptoms in people who are otherwise a good match for an ICD and meet other criteria.
Acquaviva delle Fonti, BariAges 18–90 - NCT05493605Recruiting
MRI study of heart involvement in Wilson disease
This study looks at whether Wilson disease affects the heart, using MRI scans (and possibly contrast dye). Your results may help doctors better understand cardiac (heart) involvement and how it progresses in Wilson disease.
ParisAges 18 years+ - NCT05494034Recruiting
Monitoring heart rhythms after stroke to guide care
This study uses a small implantable heart monitor to track heart rhythm in people after an acute ischemic stroke or TIA. It aims to learn how often hidden heart rhythm problems show up, which could help doctors choose better stroke prevention treatments.
AthensAges 40–100 - NCT05498675Recruiting
Sacubitril/valsartan study for high blood pressure by body size
This study tests how sacubitril/valsartan may affect heart function in people with high blood pressure, and whether results differ by body size (BMI). You may benefit by getting closer heart monitoring, though it depends on whether you fit the safety and medical criteria.
Beijing, Beijing MunicipalityAges 18–70 - NCT05506293Recruiting
Registry study for sealing leaking heart valve devices
This is a study that collects information from people who are having a minimally invasive procedure to close a leak around a heart valve replacement device. It may help doctors better understand how well this procedure works and what outcomes to expect.
CharleroiAges 16–110 - NCT05521451Recruiting
Study for adults with heart rhythm problems
This trial is a “clinical cohort” study, meaning it follows adults with certain heart rhythm issues to understand them better. Your participation may help researchers learn what to expect and how best to support people over time.
HamburgAges 18 years+ - NCT05520762Recruiting
Trial for patients after in-hospital cardiac arrest needing breathing support
This trial studies a hospital treatment for people who have a cardiac arrest while in the hospital and still need help breathing. It may help improve care right after this emergency by testing an airway resuscitation approach.
New York, New YorkAges 18 years+ - NCT05539040Recruiting
Testing why certain heart signals trigger atrial fibrillation
This trial studies abnormal electrical signals in the right upper heart chamber and how they relate to atrial fibrillation (AF). It may help improve how doctors target AF treatment during catheter ablation for people who have AF symptoms.
LondonAges 18–85 - NCT05545176Recruiting
Testing rules for stopping resuscitation after out-of-hospital arrests
This trial studies and checks decision rules doctors can use to decide when to stop CPR in patients who have an out-of-hospital cardiac arrest. It may help make those decisions more consistent and safer across Asian countries.
TaipeiAges 18 years+ - NCT05547165Recruiting
Closing a leaky heart connection early in very small babies
This trial compares an early procedure to close a heart vessel called the ductus arteriosus versus careful observation alone in very low-birth-weight preterm infants. It aims to see whether closing the vessel early can improve outcomes and be done safely.
Birmingham, AlabamaAges 1 week–1 month - NCT05547607Recruiting
Study of heart valve infection signs on heart scans
This study looks at clinical symptoms and test findings to better understand heart valve infection (endocarditis) in adults. It may help doctors recognize the condition sooner and interpret echocardiography results more accurately.
Cona, FerraraAges 18 years+ - NCT05560958Recruiting
Heart procedure study for specific BIOTRONIK EP products
This study collects real-world follow-up information after certain heart procedures that use specific BIOTRONIK equipment. It may help confirm how well these devices work in everyday care and improve future recommendations.
FriedrichshafenAges 18 years+ - NCT05564793Recruiting
Noninvasive heart mapping to improve CRT outcomes
This trial tests whether a special noninvasive heart “mapping” test done on the body can help improve outcomes for people who need a CRT device. It studies whether mapping before implantation can better guide or predict how well the CRT will work.
AmsterdamAges 18–85
Hear when a new Cardiac trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for cardiac?
- Yes. Clin2 currently lists 1,308 recruiting cardiac studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiac trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiac trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.