Testing a shot of epinephrine during out-of-hospital CPR
Treatments studied
Part of Heart & circulation clinical trials.
This trial studies whether giving a medicine shot (epinephrine) into the muscle helps children who have a cardiac arrest outside the hospital. It’s meant for emergency situations where CPR is started right away by trained responders.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be a child from 1 day old up to 17 years old
- Have a cardiac arrest happening outside the hospital (not in a hospital)
- First responders started CPR and you continued CPR for at least 1 minute
- CPR must be given by trained professionals (such as paramedics, fire, or police)
- The cardiac arrest must NOT be clearly caused by a traumatic injury (like a major crash or obvious physical trauma)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether giving a low dose of epinephrine (a medicine that helps restart the heart) during a cardiac arrest can improve brain recovery. It compares standard treatment with adding this low dose to see if more patients recover without brain damage.
This study looks at whether a higher dose of epinephrine (a medicine that helps restart the heart) is better than the standard dose for people whose heart has stopped outside of a hospital. It aims to see if one dose leads to better survival and recovery.
This trial tests whether a combination of three medications (epinephrine, vasopressin, and a steroid) given by paramedics before arriving at the hospital can improve survival for adults who have a cardiac arrest outside of a hospital. It is only for patients who are treated by specially trained paramedics and meet specific medical criteria.
This trial compares two medications, epinephrine and isoprenaline, given to people who have a cardiac arrest (heart stops beating) with a specific heart rhythm called asystole (flatline). The goal is to see which drug is better at restarting the heart and improving chances of survival.
This study tests emergency treatments for people who have had a cardiac arrest (heart stops beating) outside the hospital. It looks at two groups: people whose hearts stop despite CPR efforts, and people whose hearts have restarted. The goal is to see if these treatments can help patients survive and recover better.
This trial tests whether giving ECMO (a heart-lung machine) to people in cardiac arrest before they reach the hospital can improve survival. It might be an option if you had a witnessed heart attack and received CPR quickly.
Hear when a new Pediatric Out-of-Hospital Cardiac Arrest trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.