Clinical trials
Cardiac clinical trials
Below are recruiting cardiac clinical trials, each written for real people, not researchers. We’re tracking 1,308 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05166954Recruiting
Bariatric surgery and heart function in people with high blood pressure
This study looks at whether bariatric (weight-loss) surgery improves heart function in people who have high blood pressure. You may be able to join if you’re already a bariatric surgery patient at the study hospital and meet the health and medication criteria.
Beijing, Beijing MunicipalityAges 17–70 - NCT05184790Recruiting
Using imaging during radiation therapy to improve AI planning
This study tests how well an artificial intelligence system can use special X-ray images taken during certain radiation treatments to improve care. You may qualify if you’re having radiation for specific conditions and your treatment center uses the required imaging steps.
Saint Leonards, New South WalesAges 18 years+ - NCT05189262Recruiting
Study of blood changes during heart surgery bypass
This study looks at whether a machine used during heart surgery (cardiopulmonary bypass) causes red blood cells to break down. The goal is to better understand these blood changes and what they might mean for patients during and after surgery.
Baltimore, MarylandAges 18–88 - NCT05208567Recruiting
Testing heart ultrasound in older adults with weak heart pumping
This trial uses a heart ultrasound test to find people who may have weak heart pumping function, especially in a multi-ethnic community. It may help improve how doctors detect this condition earlier using ultrasound images.
LondonAges 65 years+ - NCT05223413Recruiting
Remote arm treatment to protect the heart during chemo
This trial studies whether a simple “remote conditioning” treatment on the arm can help protect the heart while you receive chemotherapy that includes anthracyclines. If you’re at higher risk for heart damage from chemo, this may reduce risk and help monitor heart function over time.
AarhusAges 18–99 - NCT05236153Recruiting
Study of heart valve procedure in repaired Tetralogy of Fallot
This study looks at how a transcatheter pulmonary valve replacement works in people with repaired Tetralogy of Fallot or double outlet right ventricle. The goal is to better understand the heart’s anatomy and how it may affect the valve procedure.
Boston, MassachusettsAges Any age - NCT05239364Recruiting
Ablation for an abnormal heart rhythm after prior AF surgery
This trial tests a procedure to “ablate” (treat) a specific fast heart rhythm in the upper chambers of the heart that happens after previous atrial fibrillation (AF) ablation or heart surgery. It may help by stopping the rhythm and reducing symptoms, while doctors check how well the targeted mapping and ablation work.
Hamburg, Free and Hanseatic City of HamburgAges 18 years+ - NCT05262907Recruiting
Study of heart imaging in people with one pumping ventricle
This study uses routine heart scans (either echocardiogram or MRI) to better understand single-ventricle heart conditions. It may help improve how doctors evaluate and monitor your heart over time.
Durham, North CarolinaAges Any age - NCT05263804Recruiting
Study uses MRI and blood clues after ischemic stroke
This study looks for biological and imaging markers that may predict heart/vascular outcomes after an ischemic stroke. You may join if you are eligible for standard stroke treatment and can complete planned follow-up and MRI scans.
BronAges 18 years+ - NCT05265520Recruiting
Pacing strategy study for certain heart failure patients
This trial tests a pacing approach designed to improve how the heart beats in some people with heart failure and a specific heart rhythm pattern on ECG. If you already need a device (CRT-D) based on your results, the study may help see whether this pacing correction improves outcomes.
Phoenix, ArizonaAges 18 years+ - NCT05302271RecruitingPhase 1
Testing gene therapy for Friedreich’s ataxia heart disease
This Phase 1 trial tests an AAV gene therapy that aims to improve heart problems caused by Friedreich’s ataxia. You may be eligible if you have genetically confirmed Friedreich’s ataxia with measurable heart weakening but still enough heart function to safely receive treatment.
New York, New YorkAges 12–50 - NCT05336877Recruiting
Using Medicare data to study pacemaker care after implant
This study looks at Medicare claims to understand how well different pacemakers work in real-world care after they are implanted. You may be included if you are a Medicare patient who received an Aveir VR leadless pacemaker or a single-chamber ventricular pacemaker after the study began.
Sylmar, CaliforniaAges 18 years+ - NCT05346094Recruiting
MRI measurements of normal heart values
This study uses heart MRI scans to create “normal” heart measurement ranges for people who don’t have heart disease. This can help doctors better spot abnormal heart changes in the future.
Beijing, Beijing MunicipalityAges Up to 80 years - NCT05353348Recruiting
Program to treat mild anemia around heart surgery
This trial tests a combined treatment plan to improve anemia (low blood count/iron levels) before and around the time of major elective heart surgery. It may help reduce the need for blood transfusions and support safer recovery.
Hangzhou, ZhejiangAges 18 years+ - NCT05359263RecruitingPhase 2
Dapagliflozin for kidney disease to improve heart structure
This Phase 2 study tests whether dapagliflozin can improve heart structure and function in people with chronic kidney disease (CKD). Dapagliflozin is a kidney-heart medicine that may affect how the heart changes over time, measured by heart scans.
CopenhagenAges 18 years+ - NCT05366361Recruiting
Study of persistent atrial fibrillation during heart procedures
This study looks at what happens in the heart in people with persistent atrial fibrillation when they undergo an ablation or Maze surgery. It may help doctors better understand the condition and improve future care for people needing these procedures.
Stanford, CaliforniaAges 22–80 - NCT05371405Recruiting
Using computer learning to improve care for atrial fibrillation patients
This study uses machine learning (computer pattern-finding) to better understand atrial fibrillation and guide care around the time of an ablation procedure. It may help refine how doctors treat certain AF patients based on their heart patterns.
Stanford, CaliforniaAges 22–80 - NCT05373498Recruiting
Registry for children’s heart emergencies after resuscitation
This trial is a registry that collects information about children (under 18) who have congenital heart problems and need resuscitation with chest compressions. It helps doctors understand these emergencies and may improve future care for similar patients.
Leipzig, SaxonyAges Up to 18 years - NCT05377216RecruitingEarly Phase 1
Testing nerve stimulation effects during heart ablation
This trial studies how a type of nerve stimulation affects the heart’s electrical signals during a procedure to treat a dangerous fast heart rhythm (ventricular tachycardia). It may help doctors better understand safety and effects during planned ablation.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05378139Recruiting
At-home and hospital wireless monitoring for worsening health
This trial tests a system that continuously checks vital signs (like heart rate and breathing) using wireless sensors and sends automatic alerts if you seem to be getting worse. It may help clinicians spot problems sooner whether you’re being monitored at home or around a major surgery hospital stay.
Copenhagen, CopenhagenAges 18 years+ - NCT05386173Recruiting
Tests fetal aortic valve balloon surgery for severe narrowing
This trial studies whether doing a procedure before birth to open a baby’s aortic valve improves outcomes. It compares this approach in a specific group of pregnancies with severe heart flow problems seen on ultrasound.
San Francisco, CaliforniaAges 5 months–7 months - NCT05390047Recruiting
Register people with an S-ICD and follow them after implant
This trial is a registry that collects real-world information from people who receive an S-ICD (a small device under the skin) to help doctors learn how these devices perform over time. You may qualify if you already had the implant and can be followed for at least one month.
Lübeck, Schleswig-HolsteinAges 18–99 - NCT05398276Recruiting
Coaching for exercise anxiety through body-sensation exposure
This study tests whether a behavioral training approach that helps you become more comfortable with body sensations during exercise can reduce exercise anxiety. It may help people who are less active because they feel anxious when exercising.
East Brunswick, New JerseyAges 40 years+ - NCT05406635Recruiting
Imaging vs blood tests to guide heart-safe HER2 treatment
This trial compares whether special heart imaging or blood tests better helps monitor heart safety while you receive HER2-targeted therapy (like trastuzumab, with or without pertuzumab) plus chemotherapy. It may help doctors catch early heart stress and choose the safest treatment plan for you.
AalborgAges 18–90
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Common questions
- Are there clinical trials for cardiac?
- Yes. Clin2 currently lists 1,308 recruiting cardiac studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiac trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiac trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.