Clinical trials
Cardiac clinical trials
Below are recruiting cardiac clinical trials, each written for real people, not researchers. We’re tracking 1,308 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05565781Recruiting
Watch for hidden atrial fibrillation after unexplained stroke
This study uses a smartwatch and a longer heart-monitoring test (a Holter) to find an irregular heart rhythm called atrial fibrillation after a stroke whose cause is unclear. If they detect it, it may help guide better prevention and treatment to reduce future stroke risk.
Barcelona, CataloniaAges 55 years+ - NCT05568069Recruiting
Study of defibrillator implants for non-ischemic weak heart
This study looks at whether implantable defibrillators can reduce dangerous heart rhythms in people with non-ischemic cardiomyopathy (heart weakness not caused by blocked heart arteries), a heart scar, and very low pumping strength despite best treatment. It compares different approaches to choosing which patients should receive these devices.
High Wycombe, BuckinghamshireAges 18 years+ - NCT05574153Recruiting
Testing heart oxygen reserve in metabolic syndrome and healthy adults
This study measures how much oxygen your heart can use during stress and at rest using an MRI scan. It compares people with metabolic syndrome (a cluster of health risks) to people without those risks, to understand differences in heart function.
Montreal, QuebecAges 18–80 - NCT05573633Recruiting
Smartwatch test to detect irregular heartbeats after heart surgery
This study checks whether a smartwatch can spot an irregular heartbeat called atrial fibrillation soon after on-pump heart surgery. If the smartwatch works well, it could help clinicians find the problem earlier after surgery.
AmiensAges 18 years+ - NCT05574296RecruitingPhase 1
Test hydrogen gas for children needing emergency heart resuscitation
This early safety study tests whether “hydrogen” can be given to children during emergency heart resuscitation that isn’t improving with standard efforts. It’s meant to see if the treatment is safe and feasible for a very specific, life-threatening situation.
Washington D.C., District of ColumbiaAges Any age - NCT05588024Recruiting
Device-assisted CPR with head and chest elevation during arrest
This trial studies a CPR method that uses a device to help raise the head and chest during active resuscitation after cardiac arrest. It may help guide whether this technique improves outcomes for people who are not breathing normally and do not have a pulse.
Minneapolis, MinnesotaAges 18 years+ - NCT05593055RecruitingPhase 4
Test a heart and blood-pressure therapy in people with hypertension
This study looks at how mineralocorticoid-related hormone signaling affects small heart blood vessels and how efficiently the heart works in people with high blood pressure. It may help doctors understand which treatments could improve heart function in hypertension.
Boston, MassachusettsAges 18–75 - NCT05617456Recruiting
Test new ablation technology for treating irregular heart rhythm
This study tests advanced technology to improve how atrial fibrillation (AFib) is treated with a heart ablation procedure. It may help patients who are already advised to have AFib ablation by seeing how well the approach works in real clinical practice.
PisaAges Any age - NCT05629559RecruitingPhase 1/Phase 2
Study drug 4D-310 for Fabry disease with heart problems
This Phase 1/2 study tests how safe and potentially effective 4D-310 is for adults with Fabry disease who have heart involvement. It may help people who can’t tolerate standard treatments like enzyme replacement therapy (ERT) or migalastat, or who still have disease progression.
MelbourneAges 18–65 - NCT05631730RecruitingPhase 3
Flecainide plus metoprolol vs metoprolol alone for rhythm control
This trial studies whether adding flecainide to metoprolol can better reduce dangerous heart rhythm problems in people with mitral valve prolapse. It also checks safety and side effects compared with metoprolol alone.
OsloAges 18 years+ - NCT05635227Recruiting
Medications during heart surgery to help control breathing and circulation
This study looks at whether giving dexamethasone and olanzapine during certain heart surgeries can improve how blood flow and ventilation (breathing support) are managed. It’s meant to see if these medicines help the body handle heart-lung bypass more safely.
CopenhagenAges 18 years+ - NCT05647213RecruitingPhase 1
Skin biopsy study of stem-cell therapy for congenital heart disease
This early study takes a small skin sample to make a personalized type of heart stem cells in the future. It is testing whether this approach is safe and feasible for people with complex single-chamber congenital heart disease and advanced heart failure.
Rochester, MinnesotaAges 18–40 - NCT05687292Recruiting
Decision tool to shorten breathing machine time in children
This study tests whether a computer “decision support” tool can help doctors safely reduce how long a child stays on a breathing machine after heart surgery. It may help children get off mechanical ventilation sooner and recover faster.
Boston, MassachusettsAges 1 day–12 years - NCT05696652Recruiting
Exercise training study for people with heart failure
This study looks for blood and other markers that can explain how people with heart failure respond to exercise training. It may help researchers better tailor exercise or treatment plans for heart failure in the future.
Stanford, CaliforniaAges 18–89 - NCT05698901Recruiting
Testing heart blood tests and scans to monitor Fabry disease
This study checks whether certain heart-related blood tests and heart scans can help monitor people with Fabry disease. It may be useful for both people who have never received enzyme replacement therapy and those who have.
TaipeiAges 18 years+ - NCT05700201Recruiting
Study of heart health in adults with trauma symptoms
This study looks at how trauma-related symptoms (like PTSD symptoms) may affect heart health. You may be asked to do light activity—so your study team can see how your body responds.
Fort Lauderdale, FloridaAges 18 years+ - NCT05706194Recruiting
Early brain prognosis test after out-of-hospital cardiac arrest
This trial studies how to predict brain recovery early after a non-traumatic out-of-hospital cardiac arrest. The goal is to help clinicians estimate outcome sooner, which may improve decision-making during intensive care.
HelsinkiAges 18–100 - NCT05718128RecruitingPhase 4
Study of taking heart muscle samples from the inside
This trial studies patients who need an endocardial myocardial biopsy, meaning a small heart muscle sample taken from inside the heart. It’s meant for people with heart problems whose cause is not clearly known and may help doctors learn more about what’s going on.
Hangzhou, ZhejiangAges 18–80 - NCT05719454Recruiting
Pacemaker-based nerve therapy for high blood pressure
This study tests a new pacemaker programming method (nerve therapy) to help lower blood pressure. It may be an option if you need a dual-chamber pacemaker and your blood pressure stays high despite medicine.
PragueAges 18 years+ - NCT05732714Recruiting
Reduce heart event risk after major non-heart surgery
This study looks at ways to lower the chance of heart-related problems after major surgery that is not directly related to the heart. It focuses on people at higher heart risk who are expected to stay in the hospital for at least two days after surgery.
Toronto, OntarioAges 45–75 - NCT05746793Recruiting
IVF pregnancy study to prevent pre-eclampsia in high-risk women
This trial studies ways to lower the risk of pre-eclampsia (dangerous high blood pressure in pregnancy) in women who are having a first pregnancy through IVF/ICSI or who have PCOS. It’s aimed at people considered higher risk for pre-eclampsia.
BrusselsAges 18–48 - NCT05756309Recruiting
ECG patch test to improve heart rhythm detection in kids
This study checks whether a wearable ECG patch can correctly record heart electrical signals and help identify abnormal rhythms (arrhythmias) in children. If it works well, it could make future heart rhythm monitoring more accurate for pediatric patients who need regular Holter (long ECG) monitoring.
SeoulAges 4 weeks–19 years - NCT05758662Recruiting
PET-CT and heart ultrasound study valve changes after TAVI
This study looks at whether certain valve blood clots (called “subclinical leaflet thrombosis”) and different valve types are linked to valve aging over time. It uses a special PET-CT scan and an echocardiogram to measure changes in the heart valve about five years after TAVI.
CopenhagenAges 18 years+ - NCT05760924Recruiting
Testing a new heart pacing method for CRT nonresponders
This trial tests whether a different pacing approach called left bundle branch pacing can improve outcomes and heart structure changes in people who did not improve with standard biventricular CRT. It may help some patients with ongoing heart failure symptoms and weak heart pumping.
TomskAges 18–80
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Common questions
- Are there clinical trials for cardiac?
- Yes. Clin2 currently lists 1,308 recruiting cardiac studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiac trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiac trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.