Clinical trials · Pittsburgh, PA
Cardiovascular Diseases clinical trials in Pittsburgh
We’re tracking 20 recruiting cardiovascular diseases studies with a site in or near Pittsburgh — including Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Pittsburgh
- NCT07064473RecruitingPhase 3
Testing vicadrostat plus empagliflozin for diabetes, high blood pressure, and heart disease
This study tests a new pill called vicadrostat taken with another medicine (empagliflozin) to see if it helps people with type 2 diabetes, high blood pressure, and heart disease. It may reduce the risk of heart problems, but you must not have had heart failure or use certain other heart medications.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06281665RecruitingPhase 4
Aspirin after preeclampsia: the TAP trial
This trial tests whether taking low-dose aspirin after giving birth can help people who had preeclampsia. It aims to see if aspirin can lower the risk of future heart problems.
Pittsburgh, PennsylvaniaAges 18–55 - NCT07136012RecruitingPhase 3
Olpasiran trial to lower Lp(a) and prevent first heart attack or stroke
This trial tests if olpasiran can lower a type of cholesterol called Lp(a) to help prevent a first major heart attack, stroke, or other heart problems. It is for people at higher risk due to risk factors or early signs of artery disease, but who have not yet had a heart attack or stroke.
Pittsburgh, PennsylvaniaAges 50–105 - NCT07000357RecruitingPhase 3
Study of AZD0780 to reduce heart attack and stroke risk
This trial tests a new medication, AZD0780, to see if it helps prevent major cardiovascular events like heart attacks or strokes in people who already have heart or blood vessel disease, or are at high risk for a first event. It might be a good fit if your cholesterol isn't well-controlled despite current treatments.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06244199Recruiting
Starting cardiac rehab in the hospital for Veterans
This study tests a program that starts cardiac rehab in the hospital for Veterans with various heart conditions. The goal is to make rehab easier to begin, especially for those with other health issues or frailty.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06303869Recruiting
Deep brain stimulation for speech after stroke
This study tests if deep brain stimulation (a small device implanted in the brain) can improve speech and arm movement after a stroke that affected the deeper parts of the brain. It is designed for people who have trouble speaking clearly (dysarthria) from their stroke.
Pittsburgh, PennsylvaniaAges 18–75 - NCT06271590Recruiting
Drug-coated balloon for small heart artery blockages
This trial tests a special balloon coated with a drug (sirolimus) to treat blockages in small heart arteries. If the balloon is successful, it may help keep the artery open without needing a permanent stent.
Pittsburgh, PennsylvaniaAges 18–80 - NCT07517263RecruitingPhase 3
Long-term Safety Study of Pelacarsen Treatment
This study follows patients who completed an earlier pelacarsen trial to check if the treatment remains safe and well-tolerated over time. Pelacarsen is an experimental medicine being tested for heart and cholesterol health.
Pittsburgh, PennsylvaniaAges 18–100 - NCT06029348Recruiting
Brain health and resilience in middle age
This study looks at how well the brain's blood vessels work in midlife. It involves two visits to the University of Pittsburgh and includes an MRI and a mental math test.
Pittsburgh, PennsylvaniaAges 40–59 - NCT07518719Recruiting
Nutrition and Wellness Program for Kidney Disease
This study tests whether a nutrition and wellness program helps people with early-stage kidney disease manage their condition better. The program combines nutrition guidance, support for lifestyle changes, and care coordination to help protect kidney health.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT03683186Enrolling by invitationPhase 3
Long-term study of ralinepag for pulmonary hypertension
This study follows people with pulmonary arterial hypertension (PAH) to see how safe and effective ralinepag is over the long term. It may help your care team understand what to expect from continued treatment and monitoring.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT01524276Recruiting
Registry to track outcomes of Medtronic medical devices
This is a follow-up registry that collects information from people who have (or will receive) an eligible Medtronic device. It helps the company and doctors better understand how the device works in real-world use.
Pittsburgh, PennsylvaniaAges Any age - NCT06526195Recruiting
A study of CardioMEMS and HeartMate 3 for advanced heart failure
This trial tests if a combination of a tiny lung-artery pressure sensor (CardioMEMS) and a mechanical heart pump (HeartMate 3) is safe and effective for people with advanced heart failure. If you qualify, you'll either get the heart pump plus standard medical therapy, or continue with standard therapy alone and have your pressure monitored remotely.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT04286516Recruiting
Brain and robot training for arm movement after stroke
This study tests whether brain stimulation and robotic/arm training can improve arm movement in people who had a stroke. It may help strengthen movement and coordination by targeting brain pathways related to arm control.
Pittsburgh, PennsylvaniaAges 45–90 - NCT04262206RecruitingPhase 4
Testing how statins affect outcomes in adults 75 and older
This trial studies whether cholesterol-lowering medicine (a statin, specifically atorvastatin) improves health and benefits in people age 75 and older in everyday life. It may help doctors understand which older adults benefit most and how to use these medicines safely.
Pittsburgh, PennsylvaniaAges 75 years+ - NCT03142152Recruiting
Mitral valve implant for heart failure with leaky mitral valve
This trial tests whether a device called the Carillon Mitral Contour System can help people with heart failure caused by a mild-to-moderate leaky mitral valve. You’d be compared against a control group, and the goal is to improve heart failure symptoms and outcomes.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05472597Enrolling by invitation
Follow-up study about heart health after pregnancy
This study is continuing follow-up interviews and surveys to learn about heart health after pregnancy. If you already took part before, it may help researchers understand how postpartum health changes over time.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06742723RecruitingPhase 3
Study of baxdrostat and dapagliflozin for kidney disease and high blood pressure
This trial tests if combining baxdrostat with dapagliflozin helps protect kidney function and reduce heart risks in people with chronic kidney disease and high blood pressure. It's for adults who are already taking standard blood pressure medications.
Bridgeville, PennsylvaniaAges 18 years+ - NCT07037433RecruitingPhase 3
Heart protection study for people with heart disease and overweight
This study tests a new weekly injection (maridebart cafraglutide) to see if it helps lower the risk of heart problems in people with heart disease and overweight. It is for adults who have had a heart attack, stroke, or artery blockages and also have a BMI of 27 or higher.
Beaver, PennsylvaniaAges 45–99 - NCT07181109RecruitingPhase 3
Study of zilebesiran for high-risk hypertension patients
This trial tests a new medicine called zilebesiran for people with high blood pressure that isn't well controlled. It may be an option if you have heart or blood vessel disease, or are at high risk for it.
Uniontown, PennsylvaniaAges 18 years+
Hear when a new Cardiovascular Diseases trial opens near Pittsburgh, PA
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Cardiovascular Diseases trials in other cities
Where these studies are running near Pittsburgh
Institutions with a site for the recruiting cardiovascular diseases studies listed above.
- Allegheny General Hospital · 3 studies
- University of Pittsburgh Medical Center · 3 studies
- Heritage Valley Medical Group · 2 studies
- Preferred Primary Care Physicians, Inc. · 2 studies
- Research Site · 2 studies
- University of Pittsburgh · 2 studies
- VA Pittsburgh Healthcare System · 2 studies
- Allegheny Health Network
What taking part in a cardiovascular diseases study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting cardiovascular diseases studies in Pennsylvania.
Common questions
- Are there cardiovascular diseases clinical trials near Pittsburgh?
- Yes. We're currently tracking 20 recruiting cardiovascular diseases studies with a site near Pittsburgh, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a cardiovascular diseases study near Pittsburgh?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Pittsburgh to take part?
- Not necessarily. These studies have a site near Pittsburgh, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a cardiovascular diseases trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New cardiovascular diseases studies open near Pittsburgh regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.