Clinical trials
Central Sensitization clinical trials
Below are recruiting central sensitization clinical trials, each written for real people, not researchers. We’re tracking 23 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06948903Recruiting
Fibromyalgia, brain sensitivity and thinking
This study looks at how the brain's pain sensitivity (central sensitization) relates to memory and thinking problems in people with fibromyalgia. Participating could help doctors understand and treat these symptoms better.
Istanbul, UskudarAges 18–65 - NCT06851091Recruiting
Fibromyalgia study on pain sensitivity and balance
This study looks at how fibromyalgia affects your sensitivity to pain and your sense of balance. It may help find better ways to treat these symptoms.
Istanbul, ÜsküdarAges 18–65 - NCT06770634Recruiting
Pain sensitivity and related factors in lipedema
This study looks at how pain sensitivity (central sensitization) affects people with lipedema. It aims to understand what factors are linked to increased pain in this condition, which might help improve care.
Istanbul, ÜsküdarAges 18–65 - NCT07468097Recruiting
How metabolism affects pain in women with lipedema
This study looks at how metabolic health (like blood sugar and thyroid function) may influence pain and sensitivity in women with lipedema. It aims to better understand these links to improve treatment approaches.
Istanbul, PendikAges 18 years+ - NCT07313280Enrolling by invitation
PTSD and chronic pain therapy study for women
This study looks at how a psychological program can help women with chronic pain conditions linked to central sensitization (where the nervous system stays on high alert) and PTSD. It aims to reduce pain and stress symptoms.
Málaga, MálagaAges 18–65 - NCT04014829Recruiting
Study of pain processing after planned hysterectomy
This trial looks at how the nervous system and fear of pain may affect pain after a planned hysterectomy. If you qualify, you may be asked about pain levels and pain sensitivity to better understand who may have more pain recovery challenges.
SingaporeAges 21–80 - NCT06893822Recruiting
Griffonia simplicifolia for pain in healthy volunteers
This trial tests if a natural supplement called Griffonia simplicifolia can change how your body processes pain. It is looking for healthy people to take part.
GrazAges 18–99 - NCT07109843Recruiting
Boswellia for pain and sensitivity in healthy volunteers
This trial tests whether a supplement called Boswellia serrata (frankincense) can change how your body processes pain and touch. It is for healthy people who do not have chronic pain or use certain medications.
Graz, StyriaAges 18 years+ - NCT07554664Recruiting
Desk Work, Stress, and Muscle Pain With or Without Migraine
This study looks at how office work, job stress, and muscle tension relate to migraines and neck/shoulder pain in desk workers. Researchers want to understand if certain body changes (called central sensitization) connect these issues, which could lead to better ways to help office workers feel better.
Gaziantep, MerkezAges 18–65 - NCT05676827Enrolling by invitation
Study pain and stress in people with long-term jaw muscle pain
This trial looks at how long-lasting jaw (masticatory) muscle pain relates to the nervous system and emotional stress. It may help researchers understand why symptoms persist and guide future treatments.
WroclawAges 18–80 - NCT07154576Enrolling by invitation
Pelvic floor symptoms and pain sensitivity study
This study looks at how pain sensitivity relates to pelvic floor problems in women. It uses questionnaires to gather information and may help improve understanding of these conditions.
WarsawAges 18–80 - NCT05507853Recruiting
Study of body pain sensitivity during pregnancy
This study looks at “central sensitization,” which means the nervous system may become more sensitive to pain, in pregnant people. It aims to understand pain changes during pregnancy and how different factors may affect them.
GothenburgAges 18 years+ - NCT06215937Recruiting
Pain testing study for endometriosis patients
This study uses special tests to measure how your body processes pain and whether you have heightened pain sensitivity (central sensitization). It may help researchers understand pain in endometriosis better.
Vancouver, British ColumbiaAges 19–49 - NCT06994988Recruiting
Smart band-aid study for chronic pain in women
This trial tests a special band-aid that measures chronic pain. Women with chronic pain or healthy women may join to help researchers learn how this device works.
Chicago, IllinoisAges 18 years+ - NCT07057128Recruiting
Do nerve issues occur in shoulder pain syndrome?
This study looks at whether nerve-related symptoms are common in people with subacromial pain syndrome (a type of shoulder pain). You may qualify if you have shoulder pain that has lasted at least 3 months, with moderate to severe pain in the past week, and if you haven't had shoulder surgery or certain other shoulder problems.
Izmir, İzmirAges 19 years+ - NCT07100782RecruitingPhase 3
Estrogen & pain trial for endometriosis pelvic pain
This study tests whether a drug called relugolix CT can reduce pelvic pain from endometriosis. You'll have brain scans and pain tests to measure how your body processes pain. It might help if other treatments haven't worked well.
Ann Arbor, MichiganAges 18–49 - NCT07268768Recruiting
Personality, thinking, and sensitivity in headache
This study looks at how personality, thinking skills, and heightened nerve sensitivity are connected in people with headache. It aims to better understand these relationships to improve care.
Messina, SicilyAges 18–60 - NCT07495761Recruiting
Central sensitization signs in adults with autism
This study looks at whether adults with autism (without intellectual disability) experience central sensitization, a condition where the nervous system becomes overly sensitive to stimuli. It aims to understand how common this is and why it matters for treatment.
Grenoble, IsereAges 18 years+ - NCT07640620Recruiting
How nerve sensitivity relates to heel pain
This study looks at whether people with plantar fasciitis (painful heel condition) have heightened nerve sensitivity, and how this connects to their symptoms. Researchers will compare your pain patterns and nerve responses to those of healthy volunteers to better understand what drives heel pain.
IstanbulAges 18–65 - NCT07207083Enrolling by invitation
Can virtual reality exercise help restore body and mind in chronic low back pain
This trial tests whether doing exercises in a virtual reality (VR) environment can help people with chronic low back pain feel better both physically and mentally. You would use a VR headset to perform gentle movements and see how it affects your pain and fear of moving.
Seoul, SeoulAges 18–40 - NCT05454124Recruiting
Study of brain-eye learning changes in macular degeneration
This study looks at how the eye’s “central vision” area and connected brain learning/adjustment work in people with advanced macular degeneration. You may be asked to do vision testing using special eye-scanning equipment and follow study procedures that could help researchers better understand the disease.
Birmingham, AlabamaAges 18–89 - NCT07114913Recruiting
Carpal tunnel symptom location and pain study
This study looks at where carpal tunnel syndrome symptoms show up and how your body processes pain. By understanding this, doctors hope to find better ways to treat it.
Istanbul, UsküdarAges 18–65 - NCT06702800Recruiting
Using tumor models to predict breast cancer drug response
This study uses a personal lab-grown model of your tumor (called an organoid) to help predict which drugs are most likely to work for your specific breast cancer. It is open to both early-stage and advanced breast cancer patients who are about to start or are already receiving treatment.
Changsha, HunanAges 18–70
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Common questions
- Are there clinical trials for central sensitization?
- Yes. Clin2 currently lists 23 recruiting central sensitization studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a central sensitization trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a central sensitization trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.