Clinical trials
Chemotherapy clinical trials
Below are recruiting chemotherapy clinical trials, each written for real people, not researchers. We’re tracking 1,986 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07768124Recruiting
Acupoint patches for nausea in lung cancer chemo
This study tests whether acupoint patches can reduce nausea and vomiting caused by chemotherapy in people with lung cancer. Acupoints are specific spots on the body used in traditional Chinese medicine.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT04838652RecruitingPhase 2
Pembrolizumab with salvage chemotherapy for Hodgkin lymphoma
This Phase 2 study tests whether pembrolizumab combined with salvage (second-line) chemotherapy can treat people whose classical Hodgkin lymphoma has either come back after initial treatment or did not respond to initial treatment. You may benefit if you have first-relapsed or refractory classical Hodgkin lymphoma and meet other study rules.
CologneAges 18–65 - NCT07761429RecruitingPhase 2/Phase 3
Study of a new drug with chemo for cancer of unknown primary
This trial tests a new drug (F520) combined with two chemotherapy drugs for people whose cancer started in an unknown place in the body. It aims to see if the combination shrinks tumors and is safe.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07749924Recruiting
Watchful waiting vs. bladder chemotherapy for intermediate-risk bladder cancer
This study compares two approaches for people with intermediate-risk bladder cancer whose urine shows no signs of cancer after surgery. One group will be watched closely (active surveillance), while the other will receive chemotherapy directly into the bladder (intravesical chemotherapy). The goal is to see if surveillance alone can prevent unnecessary treatment while keeping the cancer controlled.
DaqingAges 18 years+ - NCT07751341RecruitingPhase 2
New drug with chemotherapy for advanced esophageal cancer
This study tests a new drug (SHR-9839) alone or combined with standard chemotherapy and another immunotherapy drug (adebrelimab) for advanced esophageal cancer. The goal is to see if this combination helps shrink tumors or slow cancer growth better than the standard treatment.
Beijing, Beijing MunicipalityAges 18–75 - NCT06609551RecruitingPhase 3
ctDNA-guided chemo choice for elderly colon cancer patients
This trial tests whether using a ctDNA blood test can help choose the best chemotherapy after colon cancer surgery for people aged 70–80. It aims to make treatment more personalized and reduce side effects.
Hangzhou, ZhejiangAges 70–80 - NCT07742332RecruitingPhase 2
Targeted therapy before surgery for EGFR-mutant lung cancer
This trial tests a combination of two targeted medicines (befotertinib and bevacizumab) before surgery for people with EGFR-mutant non-small cell lung cancer that cannot be removed right away. The goal is to see if this treatment can shrink the tumor and improve surgery outcomes.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07733505RecruitingPhase 1
Heated chemotherapy for older women with advanced ovarian cancer
This trial tests a new way to give heated chemotherapy directly into the abdomen during surgery for women aged 70 and older with advanced ovarian cancer. It aims to find a gentler treatment option that may still be effective for those who are more frail.
OdenseAges 70 years+ - NCT07726446RecruitingPhase 2
Freezing, immunotherapy, and chemo for bile duct tumors
This study tests a new treatment approach for bile duct or gallbladder cancer that has not been treated before. It combines a freezing procedure (cryoablation) with an immunotherapy drug (Relaforp Alpha) and chemotherapy to see if it can shrink tumors or slow disease progression.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT07731477Recruiting
Virtual reality mindfulness for anxiety in breast cancer chemo
This study tests if using virtual reality for mindfulness exercises can help reduce anxiety, improve comfort, sleep, and fatigue in women with breast cancer who are about to start chemotherapy. It compares VR mindfulness to standard care.
Ankara, AnkaraAges 18 years+ - NCT06632093Recruiting
Combination therapy for advanced liver cancer after standard treatment fails
This trial tests a triple combination of liver-directed chemotherapy (HAIC) plus immunotherapy (PD-1 inhibitor) and targeted therapy (Lenvatinib) for people with advanced liver cancer that has spread into the portal vein and who have already tried and failed standard treatments.
Shenyang, LiaoningAges 18–75 - NCT07714278Enrolling by invitation
Video-based rehab for chemotherapy nerve damage
This study tests a personalized rehab program using video analysis to help people with chemotherapy-induced nerve damage (numbness, tingling, weakness) improve their walking and daily life.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT07700979RecruitingPhase 3
Testing a new drug combo for stomach cancer
This trial tests a new immunotherapy drug called cadonilimab combined with chemotherapy for people with advanced stomach cancer that hasn't been treated yet. It compares this combination to chemotherapy with or without another immunotherapy drug, nivolumab.
Phoenix, ArizonaAges 18 years+ - NCT07702032RecruitingPhase 3
Study of petosemtamab plus chemo for left-sided colorectal cancer
This trial tests a new drug (petosemtamab) plus standard chemo to see if it works better than the current standard (cetuximab plus chemo) for people with advanced left-sided colorectal cancer that has not been treated yet. It is for patients whose cancer cells have no RAS or BRAF mutations.
Hot Springs, ArkansasAges 18 years+ - NCT07700901Recruiting
Acupuncture and exercise for nerve pain from chemo
This study tests if electroacupuncture (a type of acupuncture with mild electric pulses) combined with exercise can help reduce numbness, tingling, or pain caused by certain chemotherapy drugs. If you have nerve symptoms from taxane or platinum chemo and can walk on your own, this may be a good fit.
Changhua, ChanghuaAges 18–80 - NCT04335292RecruitingPhase 2
Osimertinib then chemotherapy for EGFR-mutated lung cancer
This Phase 2 study tests a treatment sequence starting with osimertinib, then using chemotherapy after it. It is meant for people with EGFR-mutated advanced lung cancer whose disease has come back or progressed, including a “rechallenge” attempt with osimertinib.
Vancouver, British ColumbiaAges 18 years+ - NCT06656624RecruitingPhase 2
Ribociclib plus hormone therapy for advanced breast cancer
This trial tests a new approach: starting with a targeted pill (ribociclib) plus hormone therapy (an aromatase inhibitor), instead of immediate chemotherapy, for women with a specific type of breast cancer (ER low-positive, HER2-negative) that is growing quickly. If eligible, you would not have received any prior treatment for your advanced cancer.
Nanjing, JiangsuAges 18–99 - NCT07688252RecruitingPhase 1
Immunotherapy and chemotherapy for newly diagnosed high-risk neuroblastoma
This trial tests a new drug combination (dinutuximab-beta plus chemotherapy) for children and young adults with newly diagnosed high-risk neuroblastoma. The goal is to see if adding this targeted therapy to standard chemo improves outcomes.
Taipei, TaiwanAges 1–30 - NCT06664476Recruiting
Learning better port-a-catheter care for chemo
This trial teaches nurses how to better care for a port-a-catheter (a small device placed under the skin to give chemotherapy). It looks at whether special training helps nurses improve their skills. If you are a nurse with at least one year of experience in an oncology unit, this might be for you.
CairoAges Any age - NCT06667154RecruitingPhase 2
Low-dose nivolumab plus chemo for early lung cancer
This trial tests a lower dose of the immunotherapy drug nivolumab (Opdivo) combined with standard chemotherapy before surgery for patients with early-stage non-small cell lung cancer (NSCLC). The goal is to see if this combination shrinks the tumor and improves outcomes with fewer side effects.
São José do Rio Preto, São PauloAges 18 years+ - NCT07673614Recruiting
Gentle brain stimulation for nerve pain from chemotherapy
This study tests a gentle brain stimulation technique called transcranial direct current stimulation (tDCS) to see if it can reduce nerve pain, numbness, or tingling caused by chemotherapy. If you've finished cancer treatment but still have these symptoms, this may help improve your quality of life.
Ann Arbor, MichiganAges 18–85 - NCT07679399RecruitingPhase 2
New combo therapy vs capecitabine for biliary tract cancer after surgery
This trial tests if a combination of immunotherapy (durvalumab), chemotherapy (GEMOX or GC), and a targeted therapy (lenvatinib) works better than standard capecitabine chemotherapy to prevent cancer from coming back after surgery for bile duct or gallbladder cancer.
BeijingAges 18–75 - NCT05904340Recruiting
Acupuncture-like electrical stimulation for nerve pain after chemo
This trial studies whether a skin-applied, acupuncture-like electrical treatment can reduce ongoing nerve pain (chemotherapy-induced peripheral neuropathy) after breast cancer chemotherapy. It may help if your nerve symptoms have not improved after finishing chemo.
Changhua, ChanghuaAges 18–80 - NCT07646626RecruitingPhase 2
New antibody drugs for advanced HER2-positive cancers
This trial tests two new antibody drugs (SSGJ-705 and SSGJ-612), alone or combined with chemotherapy, in patients with advanced cancers that have a protein called HER2. The study aims to see if this combination can shrink tumors and help patients live longer.
Hangzhou, ZhejiangAges 18–75
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Common questions
- Are there clinical trials for chemotherapy?
- Yes. Clin2 currently lists 1,986 recruiting chemotherapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chemotherapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chemotherapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.