Clinical trials
Chemotherapy clinical trials
Below are recruiting chemotherapy clinical trials, each written for real people, not researchers. We’re tracking 1,994 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04763356Recruiting
Remote monitoring to manage nerve pain after chemotherapy
This study tests whether remote check-ins (via phone/app/website) can help manage chemotherapy-related nerve pain in the hands and feet. It enrolls adults who developed nerve symptoms after certain cancer medicines and need ongoing monitoring.
Salt Lake City, UtahAges 18 years+ - NCT06849193Recruiting
Predicting treatment outcomes in advanced bile duct cancer
This study looks at how well current chemotherapy and immunotherapy work for advanced bile duct or gallbladder cancers that cannot be removed by surgery. Researchers will collect data from multiple centers to build a model that helps predict how patients may respond to treatment.
Nanjing, JiangsuAges 18 years+ - NCT05597683Recruiting
Nerve block for pain after major abdominal cancer surgery
This trial studies whether a targeted nerve block (called a quadratus lumborum block) can improve pain control after cytoreductive surgery and heat-based chemotherapy put into the abdomen (CRS and HIPEC). It may help some people use less rescue pain medicine and feel more comfortable during recovery.
SeoulAges 19 years+ - NCT07235930RecruitingPhase 3
New drug combo for advanced pancreatic cancer
This trial tests a combination of chemotherapy plus two targeted drugs (serplulimab and bevacizumab) against chemotherapy alone for pancreatic cancer that cannot be removed by surgery or has spread. This approach may help shrink or stabilize the tumor longer.
Hangzhou, ZhejiangAges 18–75 - NCT07080944Recruiting
Lymph node biopsy after chemo for inflammatory breast cancer
This trial is testing if a less invasive sentinel lymph node biopsy can replace more extensive lymph node removal in women with inflammatory breast cancer who have had chemotherapy and whose nodes appear cancer-free. This could help avoid unnecessary side effects.
MilanAges 18 years+ - NCT06875076RecruitingPhase 2
Ivonescimab plus chemotherapy for pretreated mesothelioma
This trial is testing a new immunotherapy drug (ivonescimab) combined with chemotherapy for people with mesothelioma that has already been treated. It aims to see if this combination can shrink tumors or slow the disease.
Changchun, JilinAges 1.5 years–6.3 years - NCT07072351RecruitingPhase 1/Phase 2
Radiation plus chemoimmunotherapy for gastroesophageal junction cancer
This trial tests a shorter course of radiation combined with chemotherapy and immunotherapy to shrink gastroesophageal junction cancer before surgery. It aims to make the tumor removable and improve outcomes.
Xiamen, FujianAges 18 years+ - NCT07622836Recruiting
Chemotherapy plus QL1706 for high-risk triple-negative breast cancer
This study tests whether adding a new immunotherapy drug called QL1706 to standard chemotherapy after surgery can help patients with aggressive triple-negative breast cancer that has spread to lymph nodes. The goal is to see if this combination prevents cancer from coming back.
Nanjing, JiangsuAges 18–75 - NCT05837052RecruitingPhase 2
Serplulimab plus chemo after initial treatment for lung cancer
This Phase 2 study looks at how safe and effective serplulimab (an immune medicine) combined with chemotherapy is when used as a “conversion” plan—first shrinking lung cancer, then trying to remove the main tumor with surgery. It may help some people who are not initially good candidates for surgery or focused radiation to become eligible after treatment.
Hangzhou, ZhejiangAges 18–75 - NCT05840562RecruitingPhase 3
Capsaicin skin patch vs duloxetine for nerve pain after chemo
This Phase 3 trial tests whether a capsaicin patch works better than duloxetine tablets to reduce painful nerve pain after chemotherapy. It aims to help people whose “gloves and socks” nerve pain has lasted after chemo.
AngersAges 18 years+ - NCT06953843RecruitingPhase 2
Radiation and Immunotherapy for Advanced Lung Cancer
This trial tests a combination of radiation and immunotherapy to see if it can make the immune system attack cancer throughout the body in people with advanced lung cancer that has spread to many places. It's for those whose cancer does not have certain genetic changes and who have not had uncontrolled brain metastases.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT06944587Recruiting
Personalized care for advanced pancreatic cancer
This trial is testing a new way to treat pancreatic cancer that has spread to nearby tissues but not to distant organs. It uses a tailored plan that may include chemotherapy and possibly surgery. The goal is to see if this personalized approach helps people live longer and better.
Bergen, NorwayAges 18 years+ - NCT07178808RecruitingPhase 2
Surgery and heated chemotherapy for stomach cancer
This trial tests if surgery to remove visible cancer in the belly combined with heated chemotherapy placed directly into the abdomen can help people with stomach cancer that has spread to the lining of the belly. It is for patients who are well enough to undergo major surgery and meet specific health requirements.
Gilbert, ArizonaAges 18 years+ - NCT06008119RecruitingPhase 3
Targeted pill combination for BRAF-mutated metastatic colorectal cancer
This study tests a combination of two targeted pills (tunlametinib and vemurafenib) for people with metastatic colorectal cancer that has a specific gene change (BRAF V600E) and whose cancer has grown after at least one prior treatment. The goal is to see if this drug combination can shrink tumors or slow cancer growth.
Beijing, Beijing MunicipalityAges 18–70 - NCT06846450RecruitingPhase 3
Comparing radiation types for nasopharyngeal cancer
This trial compares two types of radiation therapy (IMRT or IMPT plus CIRT) to see which works better for patients with nasopharyngeal cancer that hasn't spread. It's for people who have not had radiation to the head or neck before.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06713122Enrolling by invitation
Mobile app education for gynecological cancer patients on chemotherapy
This trial tests whether a mobile app can help you manage symptoms during chemotherapy for gynecological cancer. You will use the app to learn about side effects and track how you feel.
AnkaraAges 18 years+ - NCT06656624RecruitingPhase 2
Ribociclib plus hormone therapy for advanced breast cancer
This trial tests a new approach: starting with a targeted pill (ribociclib) plus hormone therapy (an aromatase inhibitor), instead of immediate chemotherapy, for women with a specific type of breast cancer (ER low-positive, HER2-negative) that is growing quickly. If eligible, you would not have received any prior treatment for your advanced cancer.
Nanjing, JiangsuAges 18–99 - NCT07122687RecruitingPhase 2
IBI363 or Pembrolizumab with Chemo before Lung Cancer Surgery
This trial tests two different drug combinations (IBI363 plus chemo versus pembrolizumab plus chemo) given before surgery for people with a specific type of lung cancer. The goal is to see which approach works better at shrinking the tumor and helping patients recover.
Shenyang, LiaoningAges 18–75 - NCT06617936RecruitingPhase 2
Immunotherapy plus endostatin and chemo for stage III lung cancer
This trial tests a combination of an immunotherapy drug (tislelizumab), an anti-angiogenic drug (endostatin), and standard chemotherapy for people with stage III lung cancer that cannot be surgically removed. The goal is to see if this triple therapy can shrink tumors and improve outcomes.
Jinan, ShandongAges 18–75 - NCT06610734RecruitingPhase 2
Combination treatment for extensive-stage small cell lung cancer
This study tests a new combination treatment for extensive-stage small cell lung cancer. You would receive an immunotherapy drug (adebrelimab) together with chemotherapy and a very low dose of chest radiation, to see if this helps control the cancer better.
SichuanAges 18–75 - NCT01717924Recruiting
Surgery vs first chemotherapy for stomach signet ring cancer
This trial compares doing surgery first versus starting chemotherapy first for people with resectable signet ring–type stomach cancer. It aims to find which approach works better to cure the cancer and prevent spread.
LilleAges 18–80 - NCT06491082Recruiting
Chemotherapy nerve damage study in solid tumor patients
This study looks at nerve damage (neuropathy) that can happen as a side effect of chemotherapy. It aims to understand how common it is and how it affects people being treated for solid tumors.
DehradunAges 18 years+ - NCT07052669RecruitingPhase 3
Shorter Chemo-Radiation Plus Immunotherapy for Stage III Lung Cancer
This trial tests a new schedule of chemo-radiation (fewer, stronger sessions) followed by an immunotherapy drug called tislelizumab. The goal is to see if this approach works better than the standard longer schedule for people with stage III lung cancer that can't be surgically removed.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT06389721Recruiting
Preventing nerve damage from breast cancer chemotherapy
This study looks at how certain chemotherapy drugs affect the brain and cause nerve damage (peripheral neuropathy) in people with breast cancer. The goal is to find ways to prevent or reduce these side effects so that treatment can be more comfortable and effective.
Houston, TexasAges 18 years+
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Common questions
- Are there clinical trials for chemotherapy?
- Yes. Clin2 currently lists 1,994 recruiting chemotherapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chemotherapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chemotherapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.