Clinical trials
Children, Only clinical trials
Below are recruiting children, only clinical trials, each written for real people, not researchers. We’re tracking 2,989 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02399527Recruiting
Lymphatic problem registry for tracking outcomes
This study enrolls people with certain lymphatic (lymph fluid) conditions to collect information and track how they do over time. It may help doctors better understand outcomes and improve care.
Boston, MassachusettsAges Any age - NCT02579044Enrolling by invitationPhase 1/Phase 2
Everolimus plus lonafarnib for children with progeria
This trial tests whether adding everolimus to ongoing lonafarnib improves health and slows complications in people with genetically confirmed progeria. It mainly checks safety and early signs of benefit in Phase I/II.
Boston, MassachusettsAges 1.5 years–25 years - NCT02271243Recruiting
Find the source of bloodstream infections from central line germs
This study uses special genetic testing of bacteria from blood to figure out where central-line bloodstream infections come from. Results may help doctors better identify the source and improve prevention and treatment.
Boston, MassachusettsAges Any age - NCT02650622Recruiting
Study of genetic and metabolic diseases in children
This study looks at children who may have genetic (inherited) or metabolic (body chemistry) problems, including newborn screening and episodes of trouble. The goal is to better understand these conditions and identify children who may benefit from further care.
Dallas, TexasAges 1 day+ - NCT02530073Recruiting
FETO procedure for babies with isolated left diaphragmatic hernia
This trial studies a fetal procedure (FETO) that temporarily blocks the baby’s windpipe to help lung growth before birth. It may help babies with severe lung underdevelopment from an isolated left diaphragmatic hernia (CDH) who meet specific pregnancy and fetal criteria.
Hartford, ConnecticutAges 18 years+ - NCT02316379RecruitingPhase 1/Phase 2
Breathing MRI test to map lung airspaces in adults
This early trial uses a special “breathing” MRI scan to create a detailed picture of how air moves in the lungs. It’s mainly a calibration study to set up the scan correctly, and you may help improve the test for future use.
Cincinnati, OhioAges 18 years+ - NCT02532452RecruitingPhase 2
T-cells made to fight a specific virus
This Phase 2 study gives you special “virus-targeting” immune cells (T-cells) to help your body control a current viral infection or virus that has come back (reactivated). It may help reduce the virus activity while you are immunocompromised, meaning your immune system is weaker than usual.
Akron, OhioAges 2 days+ - NCT02646839Enrolling by invitationPhase 2
Testing a gene-matched transplant approach for childhood leukemia
This trial studies a specific type of partially matched (haploidentical) stem cell transplant in children with ALL, AML, or MDS. It looks at whether using certain immune system gene patterns (KIR) and measuring leftover disease after treatment can improve outcomes and cost-effectiveness.
Los Angeles, CaliforniaAges Up to 21 years - NCT02595255Recruiting
Testing a hormone marker to predict infertility risk after childhood cancer
This study looks at whether a blood test (a hormone marker) can predict a child’s future risk of infertility after cancer treatment. If it works, it could help families and doctors plan earlier fertility and puberty-related care.
Montegnée, LiègeAges 3–14 - NCT02235857Recruiting
Device treatment study for children with focal segmental kidney scarring
This trial studies a medical device (the Liposorber LA-15) in children with focal segmental glomerulosclerosis (FSGS), a kidney condition that can cause heavy protein loss in the urine. It may help by improving disease control when standard treatments have not worked, were hard to tolerate, or can’t be used.
Loma Linda, CaliforniaAges Up to 21 years - NCT01790152Recruiting
Dexrazoxane study to monitor heart damage in cancer survivors
This study tests dexrazoxane (DRZ) to see how it affects blood and heart-related “biomarkers,” or measurable signs of heart damage, after cancer treatment. It mainly targets survivors who may be at risk for cardiomyopathy (heart muscle weakness) or related heart failure.
Birmingham, AlabamaAges Any age - NCT01306019RecruitingPhase 1/Phase 2
Gene therapy for children with severe immune deficiency (XSCID)
This trial tests a one-time gene therapy approach to help children with X-linked SCID (a serious inherited immune disorder) make better immune cells. It’s for people who don’t have a fully matched sibling donor and need long-term follow-up after treatment.
Bethesda, MarylandAges 2–50 - NCT01829724Recruiting
Brain activity study during repeated movement in some children
This study uses brain and muscle activity recordings while you do simple repeated movements. It may help researchers understand how brains work during movement in people with certain childhood injuries that affect walking and arm/leg control.
Bethesda, MarylandAges 5–100 - NCT01949129RecruitingPhase 2/Phase 3
Stem cell transplant trial for children with certain leukemia types
This trial tests whether children and teens with a specific type of acute lymphoblastic leukemia (ALL) do well after getting donor stem cells (an allogeneic transplant). It may help by using a standardized transplant approach for people in complete remission before the transplant.
Buenos AiresAges 1 month–18 years - NCT01356290RecruitingPhase 2
Drug combination for recurrent brain tumors in children
This trial tests a combination of antiangiogenic drugs (which block blood supply to tumors) for children with certain brain or spinal tumors that have returned or not responded to standard treatment. The goal is to see if this drug combo can shrink or slow the tumor.
Chicago, IllinoisAges Up to 19 years - NCT01852448Recruiting
Study genes affecting insulin in people with cystic fibrosis
This study looks at how genes may affect insulin and “incretin” hormones in people with cystic fibrosis. It may help researchers understand why some people develop blood-sugar problems and how to predict or prevent them.
Philadelphia, PennsylvaniaAges 2 years+ - NCT02098863Recruiting
Research program for people with sickle cell disease on hydroxyurea
This trial program studies sickle cell disease and how treatment works, especially for people who are already taking hydroxyurea at a stable, maximum tolerated dose. It may help researchers better understand treatment effects and side effects in real patients.
Peoria, IllinoisAges Any age - NCT01518400Recruiting
Sharing childhood cancer history to improve survivor care
This study builds a database of people who were diagnosed with cancer as children or teens. It looks at survivors who are done with treatment and currently have no evidence of disease, to help improve long-term follow-up care.
Los Angeles, CaliforniaAges Any age - NCT02040714Enrolling by invitation
Study of current treatments for Perthes hip disease
This study follows children (and teens) with Legg-Calvé-Perthes disease to learn about how today’s treatments work in real life. It may help doctors choose the best next steps for your child’s hip health.
Birmingham, AlabamaAges 1–18 - NCT01832324Enrolling by invitation
Study the causes of food allergy using blood samples
This study looks for the biological reasons behind food allergies by collecting a small amount of blood. It may help scientists better understand different types of food allergy and eventually improve diagnosis or treatments.
Philadelphia, PennsylvaniaAges 1 month–65 years - NCT01808937Recruiting
Study registry for morphea and storing DNA samples
This study is building a registry (a group record) of people with morphea and collecting DNA samples to help researchers learn more about the condition. It may help by improving understanding of causes, patterns, and future treatments.
Dallas, TexasAges Up to 90 years - NCT01401998Recruiting
Study collecting information from people with ARPKD
This study looks at medical records, imaging, and genetic testing for people with autosomal recessive polycystic kidney disease (ARPKD). It may help researchers better understand the condition and how it affects the liver and kidneys.
Washington D.C., District of ColumbiaAges Up to 18 years - NCT02048332RecruitingPhase 1/Phase 2
Donor immune cells for preventing infections after stem cell transplant
This trial studies donor-made immune cells (T-cells) given after a stem cell transplant to help your body fight infections. It aims to test how safe the treatment is and whether it supports the immune system in the months after transplant.
Akron, OhioAges 4 weeks+ - NCT00903110Recruiting
Long-term safety registry for Increlex in children
This study is a registry that follows children and teens with severe IGF-1 deficiency who use Increlex (or specific GH gene deletion situations) to better track long-term safety and effectiveness. You would likely join if your child is already starting or planning Increlex and is not in other growth-related drug trials.
Orange, CaliforniaAges 2–18
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Common questions
- Are there clinical trials for children, only?
- Yes. Clin2 currently lists 2,989 recruiting children, only studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a children, only trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a children, only trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.