Clinical trials
Children, Only clinical trials
Below are recruiting children, only clinical trials, each written for real people, not researchers. We’re tracking 2,989 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03214354RecruitingPhase 2
Stem cell transplant for children with sickle cell and ABO mismatch
This trial studies a stem cell transplant approach for children with sickle cell disease, using a sibling donor whose blood type is not compatible. It aims to see if this transplant method can safely reduce serious sickle cell complications.
Calgary, AlbertaAges 1–19 - NCT03175471Recruiting
MRI study of blood-vessel and tissue signs in child liver disease
This trial uses MRI scans to look for “biomarkers,” which are measurable signs in the liver, to better understand autoimmune liver diseases in children and teens. It may help doctors track disease and improve care by finding imaging patterns linked to illness.
Cincinnati, OhioAges 6–23 - NCT03274050Recruiting
Testing robotic surgery for children and adults needing operations
This trial studies how well and how efficiently robotic surgery works in both children and adults who need a procedure where robotic surgery is appropriate. It may help surgeons plan safer, smoother operations and improve operating-room efficiency.
Paris, ParisAges Any age - NCT03176836Enrolling by invitation
TP53 mutation imaging study for Li-Fraumeni syndrome
This study takes special body images (MRI) in people from families with Li-Fraumeni syndrome, especially those who carry a TP53 gene mutation. The goal is to see whether MRI can help spot problems earlier in a higher-risk group.
Toronto, OntarioAges Up to 18 years - NCT02991469RecruitingPhase 2
Testing sarilumab for children with systemic juvenile arthritis
This trial studies sarilumab, a targeted medicine, to help reduce symptoms in children and teens with systemic juvenile idiopathic arthritis (sJIA) who have not responded enough to current treatments. You may be considered because the study looks at how well and safely repeated doses work in pediatric patients.
San Miguel de Tucumán, Tucumán ProvinceAges 1–17 - NCT02769975Recruiting
Check children and teens with hormone and metabolism problems
This study evaluates children (and sometimes relatives) who may have hormone (endocrine) or metabolism-related conditions. It helps doctors better understand these problems by doing a clinical evaluation.
Bethesda, MarylandAges 3 months–100 years - NCT02740868RecruitingPhase 2
Breathing MRI using xenon gas to study lungs
This trial uses a special breathing MRI (you breathe a gas mixture) to measure how well your lungs work. It studies healthy kids and people with lung conditions like cystic fibrosis or asthma, and it may help researchers better understand lung function and flare-ups.
Toronto, OntarioAges 8 years+ - NCT02735824Recruiting
Genetic study of immune problems in children
This study looks for new genetic causes of immune system conditions that can run in families. If you join, researchers will collect health information (and usually samples) from children with immune concerns and from close relatives for comparison.
Zurich, Canton of ZurichAges Any age - NCT02720679Recruiting
Study genetics behind blood disorders in children and families
This study looks at genetic (DNA) factors that may contribute to certain blood disorders. You may be invited if you or a close family member is receiving care for a blood condition like MDS or MPN, and the study also includes related relatives.
Memphis, TennesseeAges Any age - NCT02743845Recruiting
Find genetic answers for rare, possibly inherited conditions
This trial looks for gene changes that may explain rare conditions, even when the diagnosis is not fully understood. It may help families who have a rare condition or who are related to someone with one.
Boston, MassachusettsAges Any age - NCT02914951Enrolling by invitation
Therapy to reduce irritability in children with autism
This trial studies whether cognitive-behavioral therapy (a structured talk therapy) can reduce irritability and anger outbursts in children with autism. It may help improve day-to-day behavior by teaching coping skills and reducing problem reactions.
New Haven, ConnecticutAges 8–16 - NCT02964494Recruiting
Congenital anemia registry for congenital dyserythropoietic anemia
This study is a registry that collects medical and lab information from people with congenital dyserythropoietic anemia (CDA), a lifelong type of anemia that can cause jaundice. It helps doctors better understand the condition and its causes, including in families where it runs.
Cincinnati, OhioAges Any age - NCT02851043Recruiting
Non-invasive monitor to measure breathing
This study tests a device that checks breathing without needles or painful procedures. It may help doctors learn how well breathing can be measured in people with mild breathing problems, or in healthy volunteers.
Wilmington, DelawareAges 11–17 - NCT02402244Recruiting
Caring registry study for children and young people with cancer
This study keeps a careful record of children, teens, and young adults with cancer (and some related growths) and may follow them over time. It helps researchers better track outcomes and future contact so care can improve.
Birmingham, AlabamaAges Up to 25 years - NCT02390765Recruiting
Study of growth, weight, and behavior in children
This study looks at how children’s growth and weight relate to thinking, mood, and behavior. It may help researchers understand what patterns affect health and development so they can guide better support for families.
Bethesda, MarylandAges 8–100 - NCT02390752RecruitingPhase 1
Early drug study for children and young adults with hard-to-treat cancers
This Phase 1 trial tests pexidartinib (TURALIO) to see how safe it is and how well it works against refractory (hard-to-treat) leukemias and solid tumors, including tumors seen with NF1 and MPNST. It mainly helps researchers learn the best way to dose the medication and gather early signals of benefit.
Bethesda, MarylandAges 3–35 - NCT02461615Recruiting
Registry for pulmonary alveolar proteinosis (PAP) patients
This study keeps a national record of people with pulmonary alveolar proteinosis (PAP). It includes one “snapshot” group and one group that follows people with autoimmune PAP and asks about symptoms and quality of life.
Cincinnati, OhioAges Any age - NCT02559752Recruiting
Computer brain testing during proton radiation for childhood tumors
This trial studies how children’s thinking and learning skills change while they receive proton beam radiation for a brain/spinal cord tumor. It uses computer-based cognitive tests to better understand brain effects during treatment, which may help future care.
St Louis, MissouriAges 4–21 - NCT02530658Recruiting
Sequencing children’s tumor and normal tissue samples
This study collects children’s normal and tumor tissue (or blood-related normal samples) and reads their DNA/RNA to look at genetic information. It may help researchers understand cancer-related changes and improve future testing, even when the goal isn’t to treat you directly.
Memphis, TennesseeAges Any age - NCT02356653RecruitingEarly Phase 1
Stem cell transplant help for children lacking a matching sibling
This expanded-access study offers a specific type of stem cell transplant preparation that removes certain immune cells (CD3 and CD19) from donor stem cells. It is for children who need a transplant but do not have a fully matched sibling donor and whose team cannot use the hospital’s usual matching device protocol.
Philadelphia, PennsylvaniaAges Up to 30 years - NCT02601339Recruiting
NIRS monitoring in premature babies with brain fluid problems
This study uses a special light-based monitor (NIRS) to track blood flow in the brain of premature infants. It compares babies in different conditions related to bleeding, fluid buildup, or other brain fluid changes to help doctors understand what monitoring can show.
Boston, MassachusettsAges birth–1 year - NCT02235623Recruiting
Testing a specific surgery for an undescended testicle
This trial studies a surgery approach (Fowler-Stephens orchiopexy) for boys whose testicle is found higher in the abdomen during a camera procedure. It may help doctors choose the best technique to move the testicle into the scrotum.
Boston, MassachusettsAges 4 months–3 years - NCT02310399Recruiting
Auditory brainstem implant for children without cochleae or hearing nerves
This study looks at whether an auditory brainstem implant (ABI) can help children hear sounds and develop listening/communication skills when the usual inner-ear hearing structures or hearing nerves are missing or not working. It may help some children who cannot benefit from a cochlear implant, but spoken language may not be the main outcome.
New York, New YorkAges 1.5 years–21 years - NCT02447874RecruitingPhase 1/Phase 2
Arginine treatment for children’s sickle cell pain
This early-phase study tests whether arginine can help control pain in children with sickle cell disease. You may be considered if your child is having a sickle cell pain episode that needs stronger pain medicine given through an IV.
Atlanta, GeorgiaAges 7–21
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Common questions
- Are there clinical trials for children, only?
- Yes. Clin2 currently lists 2,989 recruiting children, only studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a children, only trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a children, only trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.