Clinical trials · Ohio
Children clinical trials in Ohio
We’re tracking 312 recruiting children studies with a site in Ohio — including Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Ohio
- NCT05164172RecruitingPhase 3
Eptinezumab for kids with ongoing or recurring migraine
This trial studies eptinezumab, a migraine treatment, in children and teens ages 6 to 17 who already completed an earlier migraine study. It mainly helps doctors learn whether the treatment can be continued safely and effectively over time.
Cincinnati, OhioAges 6–17 - NCT05183035RecruitingPhase 3
Venetoclax for relapsed childhood AML
This trial studies venetoclax in children and young adults whose acute myeloid leukemia (AML) has come back. It aims to see how well this treatment controls the leukemia after earlier therapies.
Columbus, OhioAges 4 weeks–21 years - NCT05196035RecruitingPhase 3
Finerenone plus blood-pressure medicine for kids with kidney disease
This Phase 3 study tests whether finerenone works and is safe in children with chronic kidney disease and significant protein in the urine, when taken with an ACE inhibitor or ARB. It also studies how the medicine moves through the body and its effects over time.
Cleveland, OhioAges 6 months–17 years - NCT05219110Recruiting
More fluids for children sick with toxin E. coli
This study looks at whether giving extra (hyper) fluids early helps children with a high-risk E. coli stomach infection. The goal is to improve outcomes by supporting the kidneys during the illness.
Cleveland, OhioAges 9 months–21 years - NCT05233397RecruitingPhase 2
Actemra for children and young adults with craniopharyngioma
This trial studies Actemra (tocilizumab) to slow or shrink adamantinomatous craniopharyngioma, a brain tumor that can recur after treatment. You may be eligible if you’re within the age range and have measurable tumor on scan, with specific rules about prior therapy and recovery.
Columbus, OhioAges 1–39 - NCT05235165RecruitingPhase 3
Surgery choice for lung spread of osteosarcoma
This Phase 3 trial compares two ways to remove lung metastases (open surgery vs keyhole surgery) in people with osteosarcoma. It aims to see which approach works better and is safer for patients with a limited number of lung spots that can be removed.
Akron, OhioAges Up to 50 years - NCT05250180Recruiting
Animal-assisted therapy for kids after brain injury
This study looks at whether guided time with therapy animals helps children recover after an acquired brain injury, and what factors affect whether it works. Families may be asked to allow animal sessions and track responses over time.
Cincinnati, OhioAges 4–24 - NCT05277272Recruiting
Registry study for children with HLH
This study is a disease registry that collects medical information from children who have hemophagocytic lymphohistiocytosis (HLH) or are suspected to have it. It helps doctors better understand HLH and how it affects patients over time.
Cincinnati, OhioAges Any age - NCT05286788RecruitingPhase 2
MEKTOVI for children with adamantinomatous craniopharyngioma
This Phase 2 trial tests MEKTOVI® to treat pediatric adamantinomatous craniopharyngioma (a type of brain tumor). It may help shrink or control the tumor after it has come back or grown again.
Columbus, OhioAges 1–39 - NCT05297708Recruiting
Blood pressure monitoring at home, office, and with a 24-hour device
This study compares blood pressure readings taken at home, in the doctor's office, and over a full 24-hour period using a portable monitor. It may help understand the best way to track blood pressure in children and teens with slightly high blood pressure.
Cincinnati, OhioAges 6–19 - NCT05304585RecruitingPhase 3
Chemo for children with early, low-risk fusion-negative rhabdomyosarcoma
This Phase 3 study tests a chemotherapy plan for children and teens with newly diagnosed, very low-risk or low-risk rhabdomyosarcoma that does not have certain gene fusions (FOXO1 fusion negative). The goal is to see if this treatment can work well while limiting side effects by matching therapy to early-stage risk.
Akron, OhioAges Up to 21 years - NCT05318417Recruiting
Cochlear implant study for one-sided deafness
This study checks whether cochlear implantation is safe and effective for people who have very poor hearing in one ear (single-sided deafness) while the other ear hears normally or nearly normally. You may be enrolled if you meet specific hearing test and health/surgery readiness requirements.
Columbus, OhioAges 5 years+ - NCT05386173Recruiting
Tests fetal aortic valve balloon surgery for severe narrowing
This trial studies whether doing a procedure before birth to open a baby’s aortic valve improves outcomes. It compares this approach in a specific group of pregnancies with severe heart flow problems seen on ultrasound.
Columbus, OhioAges 5 months–7 months - NCT05442567RecruitingPhase 3
Vedolizumab study for kids with ulcerative colitis or Crohn’s
This Phase 3 study tests whether vedolizumab can help children with ulcerative colitis (UC) or Crohn’s disease (CD) who improved on earlier treatment. It focuses on kids who can stay off steroid medicines and follow study visits and safety rules.
Cleveland, OhioAges 2 years+ - NCT05485155RecruitingPhase 2
Zemaira trial for adults with eosinophilic esophagus
This Phase 2 study tests Zemaira (an alpha-1 antitrypsin treatment given through an IV) to see if it improves eosinophilic esophagitis (EoE) in adults. You may be able to help researchers learn whether this treatment can reduce EoE activity when standard treatments haven’t worked.
Cincinnati, OhioAges 18–70 - NCT05503134RecruitingPhase 1/Phase 2
Donor immune cell treatment for relapsed or stubborn AML
This trial tests donated “natural killer (NK) cells,” a type of immune cell, in children and young adults with AML that has come back or did not respond to treatment. It mainly looks at safety and also studies whether the treatment can help control the leukemia.
Columbus, OhioAges 1–24 - NCT05504291RecruitingPhase 2
Treatment delivered inside the eye for retinoblastoma
This Phase 2 study tests a way to deliver cancer treatment directly inside the eye to treat retinoblastoma. It may help shrink the tumor while limiting treatment to the eye when possible.
Akron, OhioAges Up to 18 years - NCT05508971Recruiting
Personalized tonsil surgery for sleep apnea in children with Down syndrome
This study tests whether a personalized surgical approach can treat moderate to severe obstructive sleep apnea (OSA) in children with Down syndrome. The goal is to improve breathing during sleep and overall sleep health.
Cincinnati, OhioAges 2–17 - NCT05517655RecruitingPhase 4
Cystic fibrosis blood/sweat check using MRI in children
This study looks at new “imaging biomarkers” (MRI measurements) in children with cystic fibrosis (CF). It mainly aims to see how MRI findings might relate to starting the recommended CF triple-combination therapy.
Cincinnati, OhioAges 6–8 - NCT05538208RecruitingPhase 2
Children with lupus kidney inflammation using mycophenolate
This Phase 2 study tests how well the medicine mycophenolate mofetil (MMF) works for children and teens with lupus nephritis that is “proliferative” (a specific biopsy type). You may qualify if your kidney biopsy and current treatment match the study’s targets and you can follow frequent visits and testing.
Akron, OhioAges 8–20 - NCT05547165Recruiting
Closing a leaky heart connection early in very small babies
This trial compares an early procedure to close a heart vessel called the ductus arteriosus versus careful observation alone in very low-birth-weight preterm infants. It aims to see whether closing the vessel early can improve outcomes and be done safely.
Columbus, OhioAges 1 week–1 month - NCT05556642Recruiting
Liver tumor registry for children with relapsed cancer
This study collects information and may collect fresh tumor tissue to better understand and model relapsed or hard-to-treat liver tumors. Joining could help researchers develop future treatments and more personalized research for affected patients.
Cincinnati, OhioAges Any age - NCT05576948Recruiting
Study of how cerebral palsy may develop in babies
This study follows infants who already have cerebral palsy or who seem at high risk to develop it. It looks at early brain and movement signs over time, which may help doctors recognize CP sooner and plan support.
Cincinnati, OhioAges 3 months–2 years - NCT05580601RecruitingPhase 1/Phase 2
Immunotherapy trial for children with relapsed or stubborn AML
This Phase 1/2 trial tests a lab-made immune-cell treatment (NK cells) for children with acute myeloid leukemia (AML) that has come back or did not respond to treatment. It aims to help the immune system attack leukemia cells in the bone marrow, especially when standard treatments have not worked.
Cincinnati, OhioAges 2 years+
Where these studies are running in Ohio
Institutions with a site for the recruiting children studies listed above.
- Cincinnati Children's Hospital Medical Center · 16 studies
- Nationwide Children's Hospital · 12 studies
- Children's Hospital Medical Center of Akron · 4 studies
- Cleveland Clinic · 4 studies
- University Hospitals Cleveland Medical Center · 3 studies
- Dayton Children's Hospital · 2 studies
- ProMedica Toledo Hospital · 2 studies
- Rainbow Babies and Children's Hospital · 2 studies
What taking part in a children study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Children trials in other states
Common questions
- Are there children clinical trials in Ohio?
- Yes. We're currently tracking 312 recruiting children studies with a site in Ohio, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a children study in Ohio?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Ohio to take part?
- Not necessarily. These studies have a site in Ohio, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a children trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New children studies open in Ohio regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.