Clinical trials
Children clinical trials
Below are recruiting children clinical trials, each written for real people, not researchers. We’re tracking 3,086 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04602325Recruiting
Blood and brain injury biomarker study for inherited metabolic disorders
This trial studies blood and other measurable signs (biomarkers) that may reflect brain injury after certain inherited metabolic conditions. Results may help doctors better detect and understand brain effects from these illnesses, especially episodes that affect the brain.
Washington D.C., District of ColumbiaAges 7–18 - NCT04608968Recruiting
Kids’ comfort questionnaire during planned surgery
This study asks children to complete a short satisfaction questionnaire while they are having planned surgery under general anesthesia. It aims to learn how kids feel about the perioperative (before, during, and after surgery) experience, which could help improve comfort and care for future patients.
Montpellier, MontpellierAges 7–17 - NCT04621201Recruiting
Testing tumor genetics in young people with bone sarcomas
This study looks at the genetic (DNA) features of tumors in children, teens, and young adults with osteosarcoma, Ewing sarcoma, or synovial sarcoma. It may help researchers better understand these cancers by analyzing a fresh tumor sample and a blood sample.
Torino, TurinAges Up to 24 years - NCT04625907RecruitingPhase 1/Phase 2
Study testing treatment options for children and adults with RMS
This study tests different treatment approaches for rhabdomyosarcoma (RMS) in children and adults, including newly diagnosed high-risk cases, people needing radiotherapy, and people whose RMS has returned. It’s designed to find safer dosing and more effective therapy while checking whether participants can proceed based on health and timing requirements.
BrisbaneAges Any age - NCT04627766Recruiting
Check whether continuous vital-sign monitoring works in children
This trial studies whether a connected patch can continuously monitor vital signs in children in the intensive care unit (ICU) safely and effectively. It may help care teams spot changes sooner using ongoing measurements.
Montreal, QuebecAges birth–18 years - NCT04629014Recruiting
Quality of life study for kids with intestinal failure
This study looks at how children with intestinal failure feel and function day to day, using questionnaires. It aims to better understand quality of life to improve care for families managing specialized nutrition needs.
Birmingham, AlabamaAges 6 months–25 years - NCT04630392Recruiting
Treadmill and vibration therapy for children with spastic cerebral palsy
This study tests whether treadmill training, with or without whole-body vibration, can improve walking and movement in children with spastic cerebral palsy. If you qualify, the goal is to see whether this exercise approach is safe and helpful.
Atlanta, GeorgiaAges 6–17 - NCT04639388Recruiting
Learning about psychosis in children with 22q11.2 deletion syndrome
This study looks at how “psychotic disorders” (like unusual beliefs, hallucinations, or thought changes) show up in children with 22q11.2 deletion syndrome. It mainly focuses on understanding the condition and may help improve care in the future.
Lyon, Auvergne-Rhône-AlpesAges 4–13 - NCT04640987RecruitingPhase 1
Stem cell transplant with added T-cells for blood cancers
This Phase 1 study tests a stem cell transplant plan that uses donor T-cells that have been specially processed and then added back. It aims to see if this approach is safer and works better for children and adults with serious blood cancers who need a transplant.
Palo Alto, CaliforniaAges 1 month–45 years - NCT04644016RecruitingPhase 2
Cord blood transplant for children and young adults with blood cancers
This Phase 2 trial studies using a cord blood transplant after finding it is risky enough that standard treatment may not be sufficient. It may help certain children and young adults with specific leukemia, lymphoma, and some non-cancer blood/immune or inherited disorders who do not have a well-matched donor available in time.
New York, New YorkAges Up to 21 years - NCT04649242RecruitingPhase 3
Migraine pain relief study for kids and teens
This trial studies a medicine for stopping a migraine attack in children and teens. It may help families understand which treatment works best during acute (during-attack) migraine pain.
Birmingham, AlabamaAges 6–17 - NCT04655404RecruitingEarly Phase 1
Larotrectinib for children with newly diagnosed glioma with NTRK fusion
This trial tests larotrectinib, a targeted cancer medicine, in children and teens with newly diagnosed high-grade brain glioma that has an NTRK fusion. It may help shrink or control tumors by targeting a specific genetic change in the cancer.
Aurora, ColoradoAges Up to 21 years - NCT04664556Recruiting
Study of severe pneumococcal infections in children
This study tracks cases of invasive pneumococcal disease (a serious infection) in children and newborns. It may help clinicians better understand how these infections happen and guide future prevention and treatment.
CréteilAges 1 day–18 years - NCT04671212Recruiting
Using discarded bone marrow from certain orthopedic surgeries
This study looks at bone marrow cells that would otherwise be discarded during some orthopedic surgeries. It may help researchers learn more about specific blood disorders (certain types of thalassemia and sickle cell–related conditions).
Memphis, TennesseeAges Any age - NCT04691622RecruitingPhase 1
Treat chronic norovirus using donor immune cells
This Phase 1 study tests whether giving immune cells made from a donor can help children and adults with long-lasting (chronic) norovirus infection. It’s aimed at people whose immune system is weakened after a stem cell transplant, solid organ transplant, or due to primary immune problems.
Washington D.C., District of ColumbiaAges 3 months–80 years - NCT04704687RecruitingPhase 3
tDCS brain stimulation for children with ADHD symptoms
This Phase 3 study tests whether a non-painful brain stimulation method called tDCS can improve ADHD symptoms in children, and whether it helps over the long term. Your child may be able to join if they are 7–14 with a confirmed ADHD diagnosis and meet symptom and testing scores.
AmiensAges 7–14 - NCT04712812Recruiting
Study of childhood-onset hereditary spastic paraplegia
This study follows people with hereditary spastic paraplegia that started in childhood to better understand how the condition progresses over time. It may help doctors learn what to expect and how to plan care, using genetic information and family history.
Boston, MassachusettsAges Up to 30 years - NCT04715646RecruitingPhase 3
Brivaracetam study for children with hard-to-control seizures
This trial looks at how safe brivaracetam is and how well it can be used in children and teens with certain types of epilepsy that are not well controlled. It may help families who are dealing with frequent focal seizures despite taking seizure medicines.
Hawthorne, New YorkAges 1 month+ - NCT04715685Recruiting
Mind-body balance program for children with migraine
This trial studies a mind-body balance approach to help reduce symptoms and disability from pediatric migraine. You may join if your child has migraine headaches and can follow study routines, including keeping a headache diary.
Aurora, ColoradoAges 10–17 - NCT04720456RecruitingPhase 2
Ultrasound test study for high pressure in liver veins in kids
This Phase 2 trial looks at a special ultrasound approach to better understand and measure portal hypertension—high pressure in the liver’s vein system—in children with long-term (chronic) liver disease. The results may help doctors track this condition more accurately and safely.
Philadelphia, PennsylvaniaAges 6–21 - NCT04722029RecruitingPhase 1/Phase 2
Donor immune-cell therapy for stubborn adenovirus infections
This study tests whether specially matched donor T-cells can control “refractory” adenovirus (a virus) that isn’t responding to usual antiviral medicines. It may help if the infection keeps coming back or is already affecting organs like the lungs or bowel.
Columbus, OhioAges Up to 60 years - NCT04724252RecruitingPhase 2/Phase 3
Gabapentin to help children use less opioid after surgery
This study tests whether gabapentin can reduce how much opioid pain medicine children need after certain major chest or heart surgeries. If it works, it may lower opioid-related side effects while still helping with postoperative pain.
Sacramento, CaliforniaAges Up to 17 years - NCT04723654Recruiting
Wearable sensors to monitor vital signs in kids
This trial tests wearable smart sensors that continuously track vital signs in children in the hospital (especially the ICU). It may help doctors watch changes sooner and learn how well the sensors work on children during care.
Chicago, IllinoisAges Up to 18 years - NCT04730011Recruiting
Short intensive therapy for kids with obsessive-compulsive disorder
This trial studies a short, intensive therapy program for children and teens with obsessive-compulsive disorder (OCD). It may help by testing whether a focused treatment schedule can improve OCD symptoms.
Zurich, Canton of ZurichAges 8–18
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Common questions
- Are there clinical trials for children?
- Yes. Clin2 currently lists 3,086 recruiting children studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a children trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a children trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.